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Amino Acids and Proteins
Functions of Protein and AA
73
Health Care
Post-Graduate
03/18/2013

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Term
proteins
Definition
herteropolymers of amino acids
Term
CHONS
Definition
proteins contain
Term
40% skeletal
25% body organs
remainder in skin/blood
Definition
distribution of body proteins
Term
Human polypeptides and proteins
Definition
Proteins are synthesis of...
Term
NEAA
Definition
protein provides sources of N to form
Term
nine
Definition
protein has this many essential amino acids
Term
ketogenic AA's
Definition
protein makes acetyl coa as fuel from
Term
oxidoreductase
transferase
desaturases
elongases
Definition
types of enzymes in proteins
Term
Zn, Fe, Cu, as cofactors or organic molecules like B-vitamins as coenzymes
Definition
enzymes require these minerals
Term
growth hormone
insulin
all hormones are not proteins
Definition
hormones in messengers of protein
Term
contractile proteins
fibrous proteins
globular proteins
Definition
the structural elements of proteins
Term
contractile proteins
Definition
actin/myosin in cardiac, skeletal, and smooth muscles are called
Term
fibrous proteins
Definition
collage, elastin, keratin in the bon, teeth, skin, cartlidge, blood, hair, and nails are called
Term
globular proteins
Definition
myoglobin are called
Term
immunoprotiens
Definition
immunoprotectors contain
Term
Y shaped and made of 2 small light chains and 2 large heavy chains
Definition
shaped immunoproteins are
Term
proteins that combine with vitamins, minerals, FAs and other nutrients
Definition
transporter molecules are
Term
albumin
Definition
transports long chain fatty acids in the blood, transports calcium, zinc, vit B6, and tryptophan
Term
ferritin and transferrin
Definition
iron storage and transport
Term
ceruloplasmin
Definition
copper transports
Term
lipoproteins
Definition
lipid transport in blood
Term
buffers
Definition
regulation of acid base balance
Term
7.35 to 7.45
Definition
pH blood is
Term
7.2 buffered by hemoglobin
Definition
pH in RBC
Term
6.9 buffered by phosphate system and amino acids in proteins
Definition
pH in muscle cells
Term
attract water to blood
protein concentrations in blood decline, edema sets in
Definition
function of fluid balancers in protein is to
Term
enzymes
messengers
structural elements
immunoprotectors
transporter molecules
buffers
fluid balancers
other roles
Definition
functions of proteins
Term
20
Definition
there are_____ genetically coded amino acids
Term
limiting amino acid
Definition
essential amino acids present in a food in a insufficient amount
Term
essential amino acids
Definition
human cells that aren't able to synthesize 8-9 amino acids
Term
AA normally non essential
under special circumstances they must be supplied from diet when the body needs it
Definition
chacteristics of conditional amino acids
Term
phenylanine
Definition
body normally makes tyrosine from
Term
sequence of AAs in polypeptide chain
Definition
primary structure of protein is
Term
number and sequence of amino acids and chemical interactions of the amino acids
Definition
protein secondary structure
Term
coiling of molecules and bonding within molecules
Definition
tertiary structure of protein
Term
involves 2 or more polypeptide chains
Definition
quartenary structure of protin
Term
oligomer
Definition
interactions between 2 or more polypeptide chains to form an aggregate is called
Term
oligomer; has 4 subunits
Definition
hemoglobin is an
Term
begins in stomach
peptic cells secrete pepsinogen
G-cells secrete gastrin
parietal cells secrete HCI which denatures protein
Definition
describe protein digestion
Term
acid chyme enters duodnum
secretin and CCK enter bloodstream
sodium bicarbonate buffers acidic chyme
Definition
describe protein digestion in small intestine
Term
absorption may be in form of tripeptides
max absorption goes to upper end of small intestine
2/3 of digested protein is absorbed as small peptide molecules
Definition
describe AA in peptid absorption in the small intstine
Term
absorption may be in form of tripeptides
max absorption goes to upper end of small intestine
2/3 of digested protein is absorbed as small peptide molecules
Definition
describe AA in peptid absorption in the small intstine
Term
faster
Definition
peptides are absorbed_____then amino acids
Term
amino acids require transporters to enter entrocyte
Definition
describe AA absorption in the small intestine
Term
energy dependent
some transporters require sodium
AA transporters are specific for certain types of AA
competition among similar AA for absorption
Definition
characteristics of transporters in entrocyts
Term
PEPT1 transport system
Definition
the entrocyte for peptide absorption uses this system
Term
serotonin
Definition
tryptophan is a precursor to
Term
melatonin
Definition
these levels decline with age
Term
B vitamin made from the EAA tryptophan
Definition
niacin is a
Term
50
Definition
how many mg of tryptophan is needed to make one mg of niacin
Term
B6
Definition
to synthesize B vitamin this coenzyme is required
Term
melatonin
Definition
this causes you to fall asleep quick
Term
transamination
Definition
first step of synthesis of nonessential amino acids or amino degragation
Term
transamination
Definition
transfer of amino group from many amino acids to keto acid acceptors
Term
transamination
Definition
amino acid loses amino group---becomes alpha keto acid--- and alpha keto acid gains amino group---becomes amino acid
Term
transamination
Definition
catalyzed by aminotransferaseses; requires vit B6 as a coenzyme
Term
transamination
Definition
this process can feed into the TCA cycle
Term
NEAA
Definition
amino groups from most AA's can be added to alpha keto acids to yield
Term
neaa
Definition
amino group transferred to pyruvate or AKG form alanine or glutamatic to form
Term
neaa
Definition
excess amino groups can be deaminatd and made into urea in liver---excreted in urine to make
Term
carbon skeleton
Definition
amino acids w/o amino group
Term
pyruvate
Acetyl CoA
intermediates of the TCA cycle
acetoacetate
Definition
carbon skeletons are degraded to these end products
Term
glucose
Definition
glucogenic skeletons make
Term
Acetyl CoA
Definition
ketogenic amino acids form
Term
deamination
Definition
removal of an amino group with no direct transfer to another compound
Term
deamination
Definition
ammonia is converted to urea for excretion process
Term
deamination
Definition
process when amino grop and H is removed
Term
oxidized in tca cycle
used for gluconeogenesis
converted to fatty acid
Definition
remaining carbon skeletons in this deamination process
Term
deamination
Definition
this process form ammonia
Term
urea
Definition
deaminated amino acids make
Term
urea
Definition
major/critical function of liver is synthesis of
Term
urea cycle
Definition
this process removes ammonia from the body
Term
deamination reactions in the body
chesse/processed meats
bacterial degragation
heat production
Definition
sources of ammonia
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