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Alterations of the Liver, Gall Bladder and Pancreas
BIO 347 Dr. Pak
25
Pathology
Undergraduate 3
04/28/2014

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Cards

Term
Livers job is to....
Definition
Maintain the body's metabolic homeostasis
Term
4 things the liver does
Definition
EXCRETE bile (bilirubin,lipids)
METABOLIZE carbs,fats, proteins
STORE carbs, lipids (glycogen)
SYNTHESIZE proteins (albumin/compliment)
Term
Functional unit of the liver
Definition
Lobules
Term
What 3 vessels are in the portal triad
Definition

Hepatic A

Portal V

Bile duct

Term
kupffer's cells
Definition
Macrophages in the liver
Term
Basic stucture of the lobules
Definition
[image]
Term
hepatic encephalopathy
Definition
ammonia/nitrogen/Toxic stuff is not filtered out by the liver and thus hurts the CNS
Term
Liver cells _______ regenerate
Definition
CAN
Term
Cirrhosis of the liver
Definition
scarring of the liver due to injury
Term
Liver tumors are generally primary or secondary?
Definition
Secondary
Term
Bilirubin metabolism
Definition
Spleen=Break down of RBC>heme+globin>heme-Iron>bilirubin
Blood= Bilirubin+albumin (unconjugated)
Liver= Bilirubin (conjugated)> bile>intestine
Term
Conjugated Bilirubin
Definition
water soluble Bilirubin
Emulsifier (breaks down fats)
Term
Unconjugated Bilirubin
Definition
not water soluble bilirubin
Term
Unused bilirubin is turned into...
Definition
Intestinal flora (Urobilinogen)
20% back to liver
80% poop
Term
Icterus/Jaundice/Hyperbilirubinemia
Definition
a symptom NOT A DISEASE
too much bilirubin
Term
Normal and Jaundice Bilirubin counts
Definition
Normal <1.2 mg/dL
jaundice >2-3 mg/dL
Term
3 types of jaundice
Definition
Prehepatic - unconjagated
hepatic - mixed conjugated/Alcohol/Virus
Posthepatic - conjugated/obstructive
Term
Physiologic Jaundice
Definition
During first week of life
mild unconjugated
Term
Pathologic jaundice
Definition
>15 mg/dL
premature babies
photo therapy
Term
2 causes of liver injury
Definition
Necrosis of the liver
fat accumulation
Term
Viral Hepatitis
Definition
throughout the liver
Swelling and necrosis
Term
Hep A
Definition
RNA
2-6 weeks
Infectious Hepititis
direct contact
you will get better
Term
Hep B
Definition
DNA
6-16 weeks
serum/fliud hepititis
Term
Hep D
Definition
Delta
have to have hep B first
Term
Hep E
Definition
fecal oral route
third world countries
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