Term
|
Definition
Sensitization: make IgE AB's but NO symptoms
Early Phase: rapid histamine release
Cell Recruitment: leukocytes to nasal mucosa
Late Phase: hypersecretion of mucus causing congestion |
|
|
Term
Sedating antihistamines
generation
selectivity
anticholinergic activity
2 sub groups |
|
Definition
first gen
nonselective
have anticholinergic activity
ethanolamines and alkylamines |
|
|
Term
| Ethanolamines (def. and 2 ex.) |
|
Definition
most pronounced sedative/anticholinergic action
diphenhydramine (Benadryl)
clemastine 1mg (Tavist) |
|
|
Term
| Alkylamines (def. and 2 ex.) |
|
Definition
lower sedative/anticholinregic action than ethanolamines
chlorpheniramine 4mg
dexchlorpheniramine 4mg |
|
|
Term
Non-sedating antihistamines
generation
selectivity
anticholinergic activity
2 examples |
|
Definition
2nd gen
peripherally selective
not anticholinergic
loratidine 10mg (Claratin)
pheninamine 25mg |
|
|
Term
Low sedating antihistamines
generation
1 example |
|
Definition
2nd gen
cetirizine 10mg (Zyrtec) |
|
|
Term
| Prescription Sedating Antihistamines (2) |
|
Definition
promethazine
cyproheptadine |
|
|
Term
| Perscription Non-Sedating Antihistamines (2) |
|
Definition
desloratadine (Clarinex)
fexofenadine (Allegra) |
|
|
Term
| Perscription Low Sedating Antihistamine (1) |
|
Definition
|
|
Term
| Perscription intranasal antihistamine (1) |
|
Definition
|
|
Term
OTC Mast cell stabilizer
(mast cells produce histamine) |
|
Definition
|
|
Term
| Perscription anticholinergic (1) |
|
Definition
|
|
Term
Perscription intranasal corticosteroids
MOST EFFECTIVE |
|
Definition
fluticasone (Flonase)
momestasone (Nasonex) |
|
|
Term
| Leukotriene receptor antagonist |
|
Definition
|
|
