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DAMN Boy Return That SE: Sedation (M,N,T) Seizures and Agitation (B) |
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BP Must clean Select toxic Tranny island SE: Sexual |
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TCAs tertiary amines (tricyclic antidepressants) |
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D-TIAC SE: Sexual, Sedation, Seizures, Autonomic/cardiologic, Hypotensive, Anticholinergic |
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Desi PAN Map SE: Sexual, Sedation, Seizures, Autonomic/cardiologic, Hypotensive, Anticholinergic |
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monoamines neurotransmitters |
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noradrenaline adrenaline dopamine seratonin (5-Hydroxytryptamine) |
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amino acids neurotransmitters |
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GABA Glutamate Aspartate Glycine |
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neropeptides (central neurotransmitters) |
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1. substance P 2. angiotension 3. somatostatin 4. Met-Enkephalin 5. Leu-Enkephalin 6. Leuteinizing hormone releasing hormone (LHRH) 7. Calcitonin-Gene- Related Peptide (CGRP) 8. Others |
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Paroxetine Sertraline: Venlafaxine Citalopram Escitalopram Fluoxetine Fluvoxamine |
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Duloxetine Atomoxetine Mirtazapine Nefezodone Bupropion Reboxetine Trazodone |
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Doxepin Trimipramine Imipramine Amitriptyline Clomipramine |
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Desipramine Protriptyline Amoxapine Nortriptyline Maprotiline |
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BP Must clean Select toxic Tranny island |
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Brofaromine Phenelzine Moclobemide Selegiline Tranylcypromine |
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amitriptyline (Elavil) is a parent drug of |
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brofaromine (Consonar) is a parent drug of |
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moclobemide (Aurorix, Manerix) |
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fluoxetine (Prozac) is a parent drug of |
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norfluoxetine (Seproxetine) |
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phenelzine (Nardil) is a parent drug of |
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imipramine (Tofranil) is a parent drug of |
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citalopram (Celexa) is a parent drug of |
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venlafaxine (Effexor) is a parent drug of |
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atomoxetine (Strattera) is a parent drug of |
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risperidone (Risperidal) is a parent drug of |
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thioridazine (Mellaril) is a parent drug of |
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atypical antipsychotics drugs |
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clozapine paliperidone risperidone (all above are 2nd generation drugs) |
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typical antipsychotics drugs |
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fluphenazine haloperidol pimozide thioridazine trifluoperazine chlorpromazine (all above are 1st generation drugs) |
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Which drugs used to counter balance decrease DA effect? |
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trihexyphenidyl or benztropine |
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Which drugs treating Schizophrenia but also have inherent anticholinergic effects? |
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clozapine or thioridazine or an atypical agent |
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both anticholinergic or dopaminergic agent |
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Carbatrol, Epitol, Tegretol |
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Depacon, Depakene, Stavzor |
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EPS (ExtraPyramidal Symptoms) (SE of haloperidol) |
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Parkinsonism Tardive Dyskinesia Dystonia Akathisia |
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mechanism of action of carbamazepine and valproic acid? |
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phenothiazines's 3 major subgroups |
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aliphatic: chlorpromazine piperidine: thioridazine piperazine: fluphenazine (all above treating + symptoms) |
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different groups of antipsychotic medication: |
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phenothiazines (with thiazine functional group) butyrophenone (with ketone functional group) |
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Example of butyrophenone's drugs: |
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haloperidol (treat + symptoms) risperidone (treat + and - symptoms) clozapine (treat + symptoms) (clozapine has a lot of SE -> not commonly used) |
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Drugs treating depression (antidepression drugs) |
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Akpaffiong's handout (SSRI, Atypical antidepressants, TCAs-tertiary amines, TCAs-secondary amines, MAOIs) |
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Drugs treating Schizophrenia |
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typical or atypical antipsychotic drugs phenothiazines group drugs or butyrophenone group drugs |
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Drugs treating bipolar/mania |
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lithium valproic acid carbamazepine |
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Increase GABA: -benzodiazepines group -barbiturates group -valproic acid |
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Drugs treating Parkinsonism |
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dopaminergic or anticholinergic e.g. levodopa, amantadine, bromocriptine, trihexyphenidyl, benztropine |
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short and longer acting benzodiazepines barbiturates chloral hydrate chlormethiazole p.6 of Dr. Akpaffiong's handout |
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short acting benzodiazepines |
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triazolam (Halcion) temazepam (Restoril) lormetazepam (Noctamid) |
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longer acting benzodiazepines |
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flunitrazepam (Rohypnol) nitrazepam (Alodorm) flurazepam (Dalmane) |
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What group of drugs often ended with "zepam"? |
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morphine, codeine, pathidine Dr. Akpaffiong's handout p. 17 |
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