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Agents alkylants
Antinéoplasiques
11
Pharmacology
Undergraduate 3
09/13/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
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Definition
Estramustine/Emcyt (Dérivés moutardes azotées)

*Effet estrogène, interaction Ca++*
Term
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Definition
Chlorambucil/Leukeran (Dérivés moutardes azotées)

*Éruptions cutanées*
Term
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Definition
Cyclophosphamide/Procytox (Dérivés moutardes azotées)

*CYP 2B6, 2C9, 3A4*
*Cystite hémorragique et SIADH*
*Acroléine*
Term
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Definition
Lomustine/CCNU (Nitrosourées)

*Carbocation chloroéthyle ou vinyle*
*Fibrose pulmonaire (rare)*
Term
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Definition
Busulfan/Myléran (Alkyl sulfonate)

*Fibrose pulmonaire (rare)*
Term
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Definition
Thiotépa/Thiotépa (Ethylenimine)

*TEPA = métabolite toxique*
Term
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Definition
Altretamine/Hexalen (Méthylmélamine)
Term
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Definition
Témozolomide/Temodal (Triazène)
Term
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Definition
Cisplatine/Platinol (Analogues du platine)

*Anémie, néphrotoxique, ototoxique, neurotoxique, no/vo ++*
Term
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Definition
Carboplatine/Paraplatin (Analogues du platine)

*Thrombocytopénie, no/vo++*
Term
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Definition
Procarbazine/Natulan (Autre de Agent alkylant)

*Alcool(antabuse x 1 sem), infertilité, no/vo++, rash*
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