Term
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Definition
Can be Acute or Chronic -inflammation of the renal pelvis and parenchyma -caused by infection of lower urinary tract that ascends to the kidneys --can lead to sepsis |
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Term
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Definition
Scarring of tubules leads to recurrent infections that cause one or both kidneys to shrink and lose function --can lead to end stage renal disease |
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Term
Symptoms of Pyelonephritis |
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Definition
--rapid onset Malaise Fever-often >101 Chills N/V Flank pain/CVA tenderness symptoms of UTI bacteria, blood, WBC in urine |
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Term
Symptoms of Chronic Pyelonephritis |
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Definition
Urinary frequency, dysuria, nocturia, intermittent fever, back and flank barriers |
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Term
Diagnostic Tests for Pyelonephritis |
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Definition
UA and C&S Blood Cultures Ultrasound Kidneys |
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Term
Treatment of Pyelonephritis |
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Definition
Mild symptoms: oral antibiotics for 10-14 days Severe symptoms (complicated by dehydration, fever, N/V): inpatient with IVPB antibiotics for several days and the orals for 2-3 weeks -based on C&S |
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Term
Polycystic Kidney Disease (PKD) |
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Definition
Genetic kidney disorder -Adult and Child onset |
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Term
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Definition
Autosomal Recessive -present at birth -may be diagnosed prenatally or in infancy -rare -progresses rapidly, often requires transplant |
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Term
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Definition
Autosomal Dominant -common -symptoms arise by age 40-50 -occurs in both men and women |
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Term
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Definition
Fluid filled cysts form- affect kidney function and eventually other body parts -cysts enlarge and so do kidneys (cause compression/damage to vessels and nephrons) |
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Term
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Definition
Increased risk of Diverticular disease, subarachnoid hemorrhage, heart valve abnormality |
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Term
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Definition
Abd/flank pain hematuria proteinuria polyurea/nocturia Bilateral kidney enlargement (palpable) HTN UTI & Renal calculi -progresses to ESRD |
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Term
Diagnosis/Prognosis of PKD |
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Definition
Family Hx Ultrasound Intravenous pyelogram (IVP) CT Scan -50% will progress to ESRD by age 60 |
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Term
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Definition
Prevent damage from meds, uti, obstruction, HTN Early: encourage fluids, later restriction Renal diet: low sodium, low potassium, restricted protein Can drain cysts Dialysis/transplant |
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Term
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Definition
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Term
Symptoms of Urinary Calculi |
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Definition
Pain (abdominal and flank) Renal Colic-acute, severe flank pain that radiates hematuria Dysuria N/V Fever, chills (if UTI is present) Mild shock |
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Term
Diagnosis of Urinary Calculi |
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Definition
UA/C&S/pH Stone Analysis 24hr.Urine Serum Ca+ KUB Ultrasound CT scan IVP Cystoscopy BUN/Creat. |
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Term
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Definition
Inflammation of the Liver -most commonly caused by a virus -can be acute or chronic |
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Term
Incubation period of Hepatitis |
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Definition
No signs, virus replicates |
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Term
Prodromal/Preicteric Phase of Hepatitis |
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Definition
(1-21 days pre-jaundice) -malaise, fatigue -anorexia and weight loss -GI symptoms: N/V, diarrhea or constipation Muscle/body aches, flu-like symptoms Mild RUQ pain |
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Term
Icteric Phase of Hepatitis |
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Definition
Begins 5-10 days after onset of symptoms -Jaundice -Pruritis: itching -light brown/clay colored stool -brown urine |
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Term
Convalescent Phase of Hepatitis |
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Definition
lasts several weeks post-jaundice (resolution) -energy increases -pain subsides, GI s/s minimal |
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Term
Hepatitis A Route/Source/Infectivity |
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Definition
Fecal/Oral poor hygiene/sanitation Infectivity: up to 2 weeks before and 1 week after No carrier-typically benign/self limiting |
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Term
Hepatitis B Route/Source/Infectivity |
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Definition
Blood/body fluids -needles, sex, tattoos, piercings, etc. Infectivity: before/after ~4-6 months, carrier for life --increased risk of developing liver CANCER! |
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Term
Hepatitis C Route/Source/Infectivity |
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Definition
Blood/Body fluids needles, blood transfusions Infectivity: 1-2 weeks before/after, carrier for life --Primary cause of chronic hepatitis, cirrhosis, liver cancer |
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Term
Hepatitis E Route/Source/Infectivity |
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Definition
Recal/Oral -contaminated drinking water Infectivity: unknown, similar to to HAV |
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Term
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Definition
Rapid onset -rare clinical syndrome resulting from severe impairment or necrosis of liver cells and liver failure --Caused by HBV with HDV rapidly progresses to liver failure- within 2-3 weeks |
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Term
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Definition
Immune response against the liver -causes chronic inflammation, necrosis, fibrosis, scarring -often with other autoimmune disorder --can lead to cirrhosis, liver failure |
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Term
Vaccine Options for Hepatitis |
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Definition
Hep A: 2 doses recommended Hep A and B: TWINRX 3 injection series Hep B: 3 Injection series-most effective |
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Term
Postexposure TX for Hepatitis |
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Definition
Immunoglobin for HAV HBIG for HBV Interferon Alpha Ribavirin |
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