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Adult 1 Quiz 1
Med-Surge Electrolytes, Respiratory, and Pre-Op
160
Nursing
Undergraduate 2
01/31/2014

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Term
Isotonic dehydration
Definition
Most common type of dehydration; fluid is lost from the plasma and interstitial fluids so intracellular fluid stays the same
Term
How are the early and late stages of renal failure different?
Definition
Early renal failure causes water loss/dehydration; late renal failure causes water retention/fluid overload.
Term
How much does 1 L of water weigh?
Definition
1 kg
Term
How much additional water is lost insensibly for every 1 degree Celsius increase in body temperature?
Definition
500 mL
Term
Normal urine specific gravity range?
Definition
1.005-1.030
Term
Cardiovascular assessment findings indicating dehydration?
Definition
Rapid, weak pulse
Low blood pressure, especially systolic
Orthostatic Hypotension
Flat neck and hand veins
Term
Integumentary assessment findings indicating dehydration?
Definition
Thick, sticky coating on oral mucus membranes
Cracks and fissures on oral mucus membranes
Tongue furrows
Term
Respiratory assessment findings indicating dehydration?
Definition
Increased respiratory rate
Term
Neurological assessment findings indicating dehydration?
Definition
Change in mental state, especially confusion in older adults
Low grade fever due to decreased blood flow to brain
Term
Lab findings indicating dehydration?
Definition
Hemoconcentration: Elevated hemoglobin, hematocrit, osmolarity, glucose, protein, BUN, Cr
Term
Drug interventions and nursing actions for dehydration?
Definition
IV fluid replacement.
Nurses monitor: Pulse rate + quality; I+O
Drugs to control the cause of dehydration (i.e. anti-diarrheal, antiemetic, etc.)
Term
Oral fluid replacement treatment for dehydration and the nurses role in this?
Definition
ORT: certain solutions have glucose and electrolytes that can be absorbed even if the patient is vomiting/having diarrhea
Nurses urge and measure small volumes of fluids every hour, evenly spaced over 24 hours, staying with the patient while they drink
Term
First nursing priority for a patient with dehydration?
Definition
RISK FOR FALLS: Monitor vitals, ortho-checks, muscle weakness, dysrhythmias, confusion
Term
Which acid-base imbalance can cause hypokalemia?
Definition
Alkalosis
*Memory trick: al K a LO sis "K lo" sounds like "K+ low"
Term
What electrolyte should you monitor if a patient has hyperinsulinism, and/or hyperalimentation/TPN?
Definition
K+
Term
What are some conditions that can cause potassium loss?
Definition
Hyperaldosteronism
Cushing's disease
Vomiting/diarrhea
Term
Name 3 drugs that cause potassium loss?
Definition
Diuretics
Digitalis
Corticosteroids
Term
What does hypokalemia due to excitable membranes, and what are the resulting problems of this?
Definition
Low potassium DECREASES excitability, leading to:
Muscle weakness
Decreased reflexes
Irritability/lethargy/confusion
Decreased peristalsis
Term
What are the nursing priorities for hypokalemia and why?
Definition
Assess respirations every 2 hours and ensure adequate oxygenation because of the weakness of respiratory muscles.
Prevent falls because of generalized muscle weakness
Monitor cardiovascular function
Term
What effects does hypokalemia have on the heart?
Definition
Dysrhythmias
Increased digoxin sensitivity
Term
What does the nurse monitor during hypokalemia?
Definition
Administration--prevent injury from IV K+
Oxygenation levels and ability to cough
I&O: "P before K"
ECG
Falls precautions
Term
How is potassium replaced in hypokalemia?
Definition
PO supplements can be mixed with liquid
Discontinue K+ wasting diuretics and replace with K+ sparing diuretics if needed
IV replacement if hypokalemia is severe:
NEVER GREATER THAN [1 MEQ/10 ML]
NEVER MORE THAN 10 MEQ/HOUR
CALL RRT IF IV SITE INFILTRATES (necrosis, phlebitis)
NEVER GIVE IM OR IV PUSH
Term
What are some of the causes of dilutional (relative) hyponatremia?
Definition
Heart failure (fluid retention)
Syndrome of Inappropriate ADH
Polydipsia (drinking too much water)
Term
What are some causes of ACTUAL losses of sodium leading to hyponatremia?
Definition
Cerebral salt wasting syndrome
Diuretics
Excessive sweating
Wound drainage, especially GI wounds
NPO status
Term
What other imbalances can cause hyponatremia?
Definition
Hyperlipidemia
Hyperglycemia
Low ADH
Term
What does low sodium (hyponatremia) do to excitable membranes?
Definition
Low sodium DECREASES excitability:
General muscle weakness
Decreased reflexes
Term
What assessment findings would indicate possible hyponatremia?
Definition
Changes in blood pressure and pulse (vague)
Increased GI motility
Change in mental status, often confusion in older adults, due to cerebral edema and increased intracranial pressure from cellular swelling
Term
How is relative hyponatremia (low sodium because of increased water dilution) treated and what is the nurses role in this?
Definition
Conivaptan or tolvaptan (diuretics that excrete just water and not salt), or ADH antagonists can be given. *Nurses must monitor potassium with these drugs
Fluid restrictions may be implemented.
Consult dietary.
Term
How is actual hyponatremia (low sodium with low or normal fluid levels) treated and what is the nurse's role in this?
Definition
Discontinue loop diuretics (RN holds dose)
IV saline (RN monitors pulse rate and quality, I&O)
IV 3%NS if imbalance is severe (RN monitors vitals, I&O, lung sounds, and labs to avoid fluid overload)
Term
Which acid-base imbalance can cause hypocalcemia?
Definition
Alkalosis (Which can also cause hypokalemia)
Term
Age-related changes that lead to fluid and electrolyte imbalances
Definition
Decreased skin integrity
Decreased GFR and urine concentrating ability
Decreased muscle mass
Decreased thirst reflex
Adrenal atrophy (poor regulation of K and Na)
Term
What are seizure precautions and when should you have them ready?
Definition
Seizure precautions: Padded side rails, washcloth or padded tongue blade, suction.
When to be prepared: High OR Sodium, + low calcium, magnesium, phosphorus
Term
What imbalances can cause relative hypocalcemia?
Definition
High phosphorus (Inverse relationship with Ca)
High protein (protein binds calcium, making it unavailable)
High citrate (blood products)
Low magnesium
Low Vitamin D
Term
Name some causes of actual calcium loss?
Definition
Lactose Intolerance
Celiac/Crohn's disease
Vomiting/diarrhea
End-stage kidney disease
Term
What happens to excitable membranes when calcium is low?
Definition
Hypocalcemia = INCREASED excitability because calcium is normally a stabilizer
Paresthesias
Twitching/cramps
Chvostek's/Trousseau's
Increased GI motility
Term
What cardiovascular changes result from hypocalcemia?
Definition
Weak pulse with abnormal rate
Hypotension
Term
What can help alleviate the cramps and twitching from hypocalcemia?
Definition
Muscle relaxants and MgSO4 (magnesium sulfate)
Term
What do drug interventions focus on for hypocalcemia?
Definition
Oral and IV replacements
Vitamin D and aluminum hydroxide to help the calcium be absorbed
Term
What nursing SAFETY interventions should be implemented for a patient with hypocalcemia?
Definition
Assess ROM
Use a lift sheet when moving
Decrease stimuli, provide quiet environment
Seizure precations
Term
What are some non-drug causes of hypomagnesemia?
Definition
Malnutrition
Starvation
Diarrhea
Steatorrhea (fat in poop)
Celiac/Crohn's disease
So basically not taking any in or losing through the GI
Term
What does low magnesium do to excitable membranes?
Definition
Hypomagnesemia INCREASES excitability because it's a membrane stabilizer along with Calcium
Increased reflexes
Psychosis, confusion, depression
Paresthesia
Cramping
Tetany and seizures
Term
What other imbalances can low magnesium cause?
Definition
Calcium and potassium
Term
Why does low magnesium cause skeletal muscle weakness and decreased GI motility if it also causes increased excitability?
Definition
Because Mg has many INTRACELLULAR functions: skeletal muscle contraction, ATP formation, etc. This lack of energy and contraction leads to skeletal muscle weakness and decreased GI motility intracellularly
Term
How can magnesium be replaced? What is the nurse's role in this?
Definition
Discontinue loop diuretics, aminoglycosides, and phosphorus-containing drugs (Hold dose)
MgSO4 can be given IV if deficiency is severe (NOT PO because of diarrhea, NOT IM because of pain and tissue damage) (RN assesses reflexes q1h to know if treatment is working)
Term
Which drugs can cause fluid overload?
Definition
Long-term corticosteroids because they are similar to aldosterone in fluid and sodium retention
Term
What GI symptoms would you find in fluid overload?
Definition
Increased motility
Enlarged liver
Term
What cardiovascular findings would expect in fluid overload?
Definition
Increased blood pressure, especially diastolic
Bounding pulse
Term
What respiratory findings would you expect in fluid overload?
Definition
Tachypnea with shallow breaths
Dyspnea
Crackles
Term
What integumentary findings would you expect in fluid overload?
Definition
Pitting edema
Pale and cool skin
Term
What neuromuscular changes would you expect in fluid overload?
Definition
Change in level of consciousness
Skeletal muscle weakness
Paresthesia
Term
What is the biggest danger of fluid overload?
Definition
It can progress to pulmonary edema and heart failure in a patient of any age or health status
Term
What are the nurse's responsibilities to a pt with fluid overload?
Definition
Watch for skin breakdown
Track I&O
Monitor for electrolyte imbalances, especially Na, K
Track weight
Teaching about food labels and daily weight journals
Term
What are the medical interventions for a patient with fluid overload?
Definition
Diuretics
Fluid and/or sodium restrictions
Term
What does HIGH potassium (hyperkalemia) do to membrane excitability?
Definition
Hyperkalemia = INCREASED excitability:
Increased GI motility
Muscle twitching and paresthesia that progresses to weakness
Term
How would you know if kidney failure is the cause of hyperkalemia?
Definition
Look at labs: If kidney failure is the cause, there will be high BUN and Creatinine, low pH, and normal or low hemoglobin and hematocrit
Term
What are the cardiovascular effects of hyperkalemia and what is the nurse's responsibility?
Definition
Ectopic beats (RN calls RRT if T waves spike)
Hypotension
Bradycardia (RN calls RRT if pulse is less than 60)
Term
What are the interventions and nursing responsibilities for hyperkalemia?
Definition
1. DC K+ containing infusions, but keep IV access open and replace with NS if needed
2. Give K+ wasting diuretics unless there are kidney issues. If there are, give kayexelate. If kayexelate is too slow and the hyperkalemia needs immediate treatment, dialysis is the only option (dialysis is also the only option if the patient is in renal failure)
3. Give hypertonic IV insulin and glucose via a central line and watch for hypokalemia and hypoglycemia
Term
What drugs/treatments can cause hyperkalemia?
Definition
ACE Inhibitors
Blood transfusions or packed RBCs
Term
What conditions can cause hyperkalemia?
Definition
Kidney failure (hold on to K+)
Adrenal insufficiency (less aldosterone)
Tissue damage/trauma (release ICF K+)
Acidosis
Hyperuricemia
Uncontrolled DM without insulin
Term
What are some causes of relative hypernatremia (dehydration)
Definition
Infection/fever/increased metabolism
Hyperventilation
Sweating
Term
What are some causes of actual hypernatremia?
Definition
Cushing's
Hyperaldosteronism
Corticosteroids
Kidney failure
Term
What is the effect of too much sodium on excitable membranes?
Definition
Hypernatremia INCREASES excitability:
Mental changes (RN should implement seizure precautions)
Muscle twitching that progresses to weakness
Slowed calcium movement, resulting in changes in blood pressure and pulse, with decreased contractility
Term
Interventions for hypernatremia?
Definition
Hypotonic IV replacement (usually 0.225%NS, sometimes 0.45%NS)
Diuretics
Adequate water intake with sodium restriction
Term
What effects do malignancies have on electrolytes?
Definition
Malignancies cause relative imbalances of too much calcium and too little phosphorus
Term
What are some causes of hypercalcemia?
Definition
Immobility
Hyperparathyroidism or hyperthyroidism (cause calcium to be taken out of bone and moved into blood)
Glucocorticoids
Thiazides
Kidney failure
Term
What effect does increased calcium have on membrane excitability?
Definition
Since calcium is a membrane stabilizer, hypercalcemia causes decreased excitability:
Change in LOC
Muscle weakness with decreased reflexes
Decreased GI motility (RN should measure ABD girth)
Term
What hemodynamic and cardiovascular effects does hypercalcemia have?
Definition
Faster clotting enzymes/risk for clots (RN should check calf circumference)
Changes in heart rate and blood pressure that start high and end up low
Term
What are some drugs that inhibit calcium resorption (resorption is the movement of calcium from the bones into the blood)
Definition
Phosphorus
Calcitonin
Bisphosphonates
NSAIDS
Term
What effect does IV NS have on calcium levels?
Definition
Decreases serum calcium because sodium flushes calcium, but not fast enough to fix someone in cardiac distress from hypercalcemia (dialysis would be needed)
Term
Other than too much intake by various routes, how could hypermagnesemia develop?
Definition
From kidney disease because magnesium is absorbed in the GI and excreted by the kidneys
Term
What are the resulting problems of hypermagnesemia and the nurse's related responsibilities?
Definition
Decreased excitability leads to skeletal muscle weakness, decreased reflexes, and lethargy/coma (RN should assess ability to breathe)
Cardiac changes lead to bradycardia, vasodilation, hypotension, and danger of cardiac arrest (RN should monitor P and BP and increase calcium to decrease cardiac side effects)
Term
Why is elastic recoil of the lungs so important?
Definition
Terminal and respiratory bronchioles have small diameters and no cartilage, so they depend entirely on lung elastic recoil to remain open
Term
What is the significance of type II pneumocytes?
Definition
They are cells in the alveolar walls that secrete surfactant. Surfactant reduces surface tension and without it, atelectasis would occur and reduce gas exchange
Term
What are the 2 systems of blood flow in the lungs?
Definition
Bronchial and pulmonary
Term
How many oxygen molecules does hemoglobin have bound when it is saturated?
Definition
4
Term
What condition produces pink, frothy sputum?
Definition
Pulmonary edema
Term
What conditions can cause hemoptysis?
Definition
Chronic bronchitis
Lung cancer
TB
Pulmonary infarction
Bronchial adenoma
Lung abscess
Term
Subcutaneous emphysema
Definition
Crepitus
Term
Conditions that increase fremitus?
Definition
Abscesses
Pneumonia
Term
Sputum cytologic exam can identify which conditions?
Definition
Cancer
Allergy
Autoimmunity
Asthma
Term
What's the difference between pulse oximetry and ABG?
Definition
Pulse ox identifies hemoglobin saturation
ABG's assess arterial oxygen
Term
Why should you use both pulse oximetry and capnography for critically ill patients?
Definition
PETCO2 can detect changes in breathing effectiveness before hypoxia can be detected with SpO2.
Term
Methoglobinemia and treatment?
Definition
Altered iron state that does not carry oxygen, resulting in tissue hypoxia, can be caused by benzocaine spray; Call RRT if this occurs after benzocaine. Treatment: 1% methylene blue 1-2 mg/kg
Term
Purpose of PFT's
Definition
Identify risks of complication before surgery
Determine cause of dyspnea
Term
Pleural effusion
Definition
Fluid in the pleural space
Term
Pneumothorax and signs/symptoms
Definition
Air in the pleural space
Signs/symptoms:
Rapid heart rate
Rapid, shallow respirations
Air hunger
Pain at end of inhalation and exhalation
Prominence that doesn't move with ventilation
Oppositely slanted trachea
New "nagging" cough
Cyanosis
Term
What is it important to know before a patient has a CT scan?
Definition
If they're allergic to shellfish or iodine
Term
What must you monitor during follow-up care after a bronchoscopy?
Definition
Return of gag reflex before NPO status is removed
Breath sounds and oxygenation
Signs of bleeding/infection
Term
After which respiratory diagnostic tests must you do a CXR?
Definition
Thoracentesis and lung biopsy
Term
Chronic hypercarbia
Definition
A patient who has gradually increased CO2 levels to 60-65 mmHg and up, who has lost the normal breathing drive mechanisms
Term
How much oxygen is it generally safe to give a patient with chronic hypercarbia?
Definition
1-2 L/min
Term
What's the most accurate way to determine need for oxygen therapy?
Definition
ABG's
Term
When do you humidify administered oxygen?
Definition
When being delivered at 4L/min or more
Term
CO2 Narcosis
Definition
The loss of sensitivity to high PaCO2 by central chemoreceptors, which then do not increase rate and depth of breathing
Term
When is it most important to monitor oxygen therapy of a patient with COPD or a similar condition that could cause a loss of the hypoxic drive to breathe?
Definition
1. IF it's the patient's first time receiving oxygen
2. If the PaCO2 levels are not known
3. During the first 30 minutes of oxygen therapy--this is when hypoventilation usually first occurs
Term
Which is a greater priority: Oxygen-induced hypoventilation, or hypoxemia?
Definition
Hypoxemia is a greater threat to life even though CO2 narcosis/oxygen-induced hypoventilation is very serious
Term
What kind of damage can prolonged exposure to high levels of oxygen cause?
Definition
Atelectasis
Pulmonary edema
Hemorrhage
Hyaline membrane formation
Term
How can the amount of oxygen administered be decreased for a patient on a mechanical ventilator?
Definition
Use CPAP, BiPAP, PEEP
Term
Absorption atelectasis
Definition
When high oxygen levels are delivered, nitrogen is diluted, and oxygen diffuses into the alveolar circulation, leaving less volume in the alveoli and causing collapse
Term
How are high-flow oxygen delivery systems different than low-flow?
Definition
High flow systems don't depend on the patient's breathing pattern to deliver adequate oxygen and tidal volume
Term
What are the forms of low-flow oxygen delivery?
Definition
Nasal cannula
Simple face mask
Partial rebreather mask
Nonrebreather mask
Term
What are the forms of high-flow oxygen delivery?
Definition
Venturi masks
Face tent
Aerosol mask
Tracheostomy collar + T piece
Term
What is the best way to deliver oxygen to a patient with chronic lung disease/danger of CO2 narcosis?
Definition
Venturi mask because it delivers the most accurate and precise oxygen concentrations
Term
What are the pro's and con's of noninvasive positive pressure ventilation?
Definition
Pro: Keep alveoli open, prevent complications associated with intubation
Con: Can cause gastric insufflation, and only mentally intact patients who can protect their own airway can use them
Term
Explain the inflammatory process of pneumonia
Definition
1. Organisms penetrate airway mucosa and multiply in alveoli
2. WBCs migrate to infection and cause capillary leak, edema, and exudate which makes the alveolar walls thicken
3. RBCs and fibrin enter and stiffen the lung, which can lead to atelectasis
4. The leaky fluids allow easy spread into the blood stream (sepsis) or pleural cavity (empyeme)
Term
2 types of pneumonia based on LOCATION
Definition
1. Lobar pneumonia: Can be in one segment or entire lobe of lung
2. Bronchopneumonia: Diffusely scattered patches around the bronchi
Term
Consolidation
Definition
Solidification, lack of air spaces on x-rays
Term
Tissue necrosis in pneumonia
Definition
Occurs when an abscess forms and perforates the bronchial wall
Term
Preventing Pneumonia
Definition
1. PPV23 vaccine if 65 or older
2. Yearly flu vaccines
3. Handwashing
4. Avoid large gatherings during flu/cold/holiday season
5. Avoid pollutants (dust, aerosoles, smoke)
6. Don't start smoking, try to quit if you do
7. Drink at least 2 L fluid/day
Term
Ventilator bundle
Definition
Hand hygiene
Oral care (complete care every 12 hours; antimicrobial and moisturizing rinse every 6 hours)
Head-of-bed elevation at least 30 degrees
Term
Why is a CXR essential for older adults in diagnosing pneumonia?
Definition
CXR is essential for early diagnosis of pneumonia in older adults because pneumonia symptoms are often vague in this population
Term
What are the priority problems for a patient with pneumonia?
Definition
1. Hypoxemia
2. Potential for airway obstruction
3. Potential for sepsis
Term
Interventions for pneumonia
Definition
Oxygen therapy
Incentive spirometry
TCDB q2h (at least)
2 L of fluid per day
Bronchodilators, inhaled or IV steroids, antibiotics, sometimes NSAIDS
Term
Important teaching points for the patient at risk for or diagnosed with pneumonia
Definition
Importance of taking antibiotics AS PRESCRIBED until they're gone
Avoiding upper respiratory tract infections (flu vaccine, avoid crowds, hand hygiene, etc.)
Vaccination (flu, pneumonia)
Smoking cessation
Term
Susceptible lung sites for TB multiplication
Definition
bronchi or alveoli
Term
Caseation necrosis
Definition
Necrotic tissue being turned into a granular mass in the center of the lesion; called a Grohn's Tubercle when it shows on X-ray of a patient with TB
Term
What are the 3 potential processes a necrotic area of lung might undergo in a TB patient?
Definition
Calcifiation
Liquefication
Cavitation
Term
Miliary TB, aka Hematogenous TB
Definition
Spread of TB throughout the body when a large number of organisms enter the blood
Term
When is a TB patient infectious/contagious?
Definition
An infected person is not infectious until manifestations of disease occur
Term
What are the focus of nursing interventions for TB?
Definition
Patient education on drug therapy adherence and infection control (Encourage them to stick it out through the nausea, fatigue, and long duration of TB drug therapy. Stress about coughing and sneezing into the arm and avoiding exposure to inhalation irritants. Let them know they can expect to have to commit to follow up treatment for at least a year with active TB treatment)
Term
When is a TB patient no longer contagious?
Definition
Usually after 2-3 weeks of consistent drug therapy as long as there are signs of clinical improvement
Term
What are the cardinal symptoms you always ask about with a respiratory health history?
Definition
Cough
Chest pain
Chills
Fatigue
Fever
Night sweats
Sputum
Term
What are the nursing actions for thoracentesis?
Definition
Pre-procedure: Consent, positioning, monitor vitals
Post-procedure: Lung sounds, signs of bleeding, CXR
Term
Nursing actions for bronchoscopy?
Definition
Pre-procedure: NPO, consent, allergies, pulse ox, remove dentures, sedation meds
Post-procedure: Monitor vitals and lung sounds, watch for hemoptysis, NPO until gag reflex returns
Term
Crackles (rales)
Definition
Indicate fluid in alveoli
Term
Rhonchi
Definition
Indicate secretions; should clear with cough
Term
Wheeze
Definition
Indicate narrowed airway
Term
Where does the inflammation of pneumonia occur?
Definition
Bronchioles and alveoli
Term
Pandemic influenza
Definition
Mostly prevalent among animals and birds, but the virus can mutate to become infectious to humans. Strict isolation precautions and antiviral drugs are used.
Term
5th leading cause of death in U.S.?
Definition
Pneumonia
Term
Risk factors for healthcare acquired pneumonia?
Definition
Hospitalization in the past 90 days
Nursing home or LTC facility resident
IV ABT, chemotherapy, or wound care in past 30 days
Hemodialysis
Term
What do you monitor if a patient received aminoglycosides ABT?
Definition
Peak and trough levels
BUN and Cr because they're nephrotoxic
I&O
Term
Primary risk factor for HAP?
Definition
Mechanical ventilation with endotracheal intubation
Term
Why would a mechanically ventilated patient be on PPIs?
Definition
To decrease the gastric pH and protect against pulmonary inflammation from aspiration of stomach contents
Term
Who are the populations most at-risk for TB?
Definition
HIV/AIDS patients
Live in crowded areas
Older age
Homeless
Lower socioeconomic status
IV drug abusers and/or alcohol abusers
Foreign immigrants
Term
Which tests would be positive for a patient with latent TB infection (LTBI) even though this patient would not be contagious?
Definition
TB SKin Test (TST)
QFT (quantiferon TB gold blood ELISA test)
Term
Signs and symptoms of TB
Definition
Fatigue
Nausea
Anorexia, weight loss
Low grade fever
Night sweats
Cough
Hemoptysis/sputum
Term
What is the difference between an AFB sputum test and a Mycobacterium tuberculosis sputum test?
Definition
The mycobacterium tuberculosis test is specific to TB (not just any acid fast bacteria) and needs 3 samples to make a definitive diagnosis
Term
List the different TB skin test findings that would indicate positive results for different populations?
Definition
5 mm induration is POSITIVE for patients with HIV, organ transplants, or any other immunosuppressants
10 mm induration is POSITIVE for recent immigrants, IV drug users, people at risk for contracting
15 mm is POSITIVE for people with no known risk factors (kids, people not around others with the infection, etc.)
Term
When do you measure the TB skin test?
Definition
48-72 hours after injection of PPD solution
Term
What treatment do you get if your PPD skin test was positive but CXR was negative?
Definition
Isoniazid and Vitamin B6 for 6 months
Term
What treatment do you get if your PPD skin test was positive and your CXR was positive too?
Definition
Give sputum samples and start on isoniazid, rifampin, pyrazinamide, and ethambutol for 6-9 months with sputum's retested every 2-4 weeks
Term
What foods should you avoid when on isoniazid?
Definition
Cheese
Chocolate
Caffeine
Red wine
Yogurt
Bananas
(tyramine-rich foods)
Term
ADE of isoniazid?
Definition
Rash
Hepatic enzyme elevation (LFT)
Hepatitis
Peripheral neuropathy
Term
What do you monitor during isoniazid therapy?
Definition
LFT's (especially AST and ALT)
Term
What increases your risk for hepatitis while on isoniazid?
Definition
Age and alcohol consumption
Term
ADE of rifampin?
Definition
N/V/D
Bleeding problems
Flu-like symptoms
Hepatitis
Term
What do you monitor during rifampin therapy?
Definition
CBC, platelets
Hepatic enzymes (LFTs)
Term
Which TB drugs decrease the effectiveness of oral contraceptives?
Definition
Rifampin and rifabutin
Term
ADE of rifabutin?
Definition
Hepatitis
Low platelets (thrombocytopenia)
Term
What do you monitor during rifabutin therapy?
Definition
CBC, platelets
LFTs
Term
Which TB drugs turn your body fluids orange?
Definition
Rifampin and rifabutin
Term
ADE of pyrazinamide?
Definition
Hepatitis
Rash
N/V/D
Hyperuricemia (gout)
Term
What do you monitor during pyrazinamide therapy?
Definition
Uric acid
LFTs
Term
ADE of ethambutol?
Definition
Optic neuritis: visual changes, can't see color, especially red and green
Term
What do you monitor during ethambutol therapy?
Definition
Baseline and monthly tests of visual acuity and color vision
Term
How is Streptomycin administered?
Definition
IM
Term
ADE of streptomycin?
Definition
Nephrotoxicity and ototoxicity (hearing loss, vestibular dysfunction)
Term
What do you monitor during streptomycin therapy?
Definition
Hearing and renal tests
Term
For which TB drug do you apply a warm compress after administering?
Definition
Streptomycin
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