Term
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Definition
alpha 1 blocker
Used to treat hypertension and urinary retention. Also decreases PVR |
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Term
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Definition
Irreversible alpha 1 blocker (also blocks alpha 2 a bit)
Used to treat Pheochromocytoma-tumor of adrenal medulla that causes increase release of catecholamine with higher NE:EPI ratio than normal |
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Term
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Definition
| alpha 1a blocker which relieves urinary retention assoc w/ benign prostate hypertrophy by specifically inhibiting contraction of prostate and involuntary sphincter |
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Term
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Definition
| block alpha 1 and alpha 2 equally |
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Term
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Definition
| alpha 2 blocker...little clinical use but used to be for ED but would also raise BP and heart rate. Makes erection by blocking inhibitory alpha-2 receptor on parasympathetic ganglion |
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Term
| Alpha 1 blocker Side effects |
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Definition
| reflex tachycardia, postural hypotension, angina, nasal congestion, inhibit ejaculation |
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Term
| Propranolol, Timolol, Nadolol |
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Definition
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Term
| Acebutolol, Betaxolol, Esmolol, Atenolol, Metoprolol |
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Definition
B1 blocker; cardio-specific (only does B2 blocking a little)
Treat hypertension and CHF |
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Term
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Definition
B1/B2 partial agonist
means acts as B-blocker when natural agonist is present, but acts as partial agonist otherwise...advantage is it avoids hypoglycemic and bradycardia effects |
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Term
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Definition
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Term
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Definition
| Chronic Glaucoma (B1 blocks aqueous humor production), hypertension, CHF, reduces MI, angina pain, migraine, hyperthyroidism induced cardiac arrythmias, performance anxiety |
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Term
| Beta Blocker Side effects |
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Definition
Bronchoconstricion-careful with asthmatics
Brdycardia-dont give to pts with conduction problems or acute CHF
Renin increases bc beta blockers reduce renal flow-this results in increased BP
Hypoglycemia from decreased glucagon and gluconeogenesis, careful with diabetics
Sexual impairment for men from reduced blood flow |
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Term
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Definition
| a1 antagonist + beta 1 antagonist so decreases PVR without causing reflex tachycardia and w/o altering cardiac output |
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