Term
Where are the adrenergic receptors located in the body? |
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Definition
They are located in the cells of muscles, such as the heart, bronchiole walls, gastrointestinal tract, urinary bladder and ciliary muscle of the eye. |
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Term
What are the four main receptors for adrenergic drugs? |
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Definition
The alpha 1, alpha 2, beta 1, beta2 |
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Term
Where are the alpha adrenergic receptors located? |
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Definition
They are located in the vascular tissues of muscles. |
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Term
What happens when alpha 1 receptors are stimulated? |
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Definition
The arterioles and venules constrict, increasing peripheral resistance and blood return to the heart. |
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Term
Where is the alpha 2 receptor located? |
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Definition
In the postganglionic sympathetic nerve endings. |
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Term
What is inhibited when the alpha 2 receptor is stimulated? |
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Definition
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Term
What does the realease of norepinephrine lead to a decrease in? |
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Definition
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Term
Where are the beta 1 receptors located? |
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Definition
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Term
What does stimulation of the beta 2 receptor cause? |
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Definition
relaxation of the smooth muscles of the lungs, resulting in bronchodilation. an increase in blood flow to the skeletal muscles. relaxation of the uterine muscle, resulting in a decrease in uterin contraction. |
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Term
What does the dopaminergic receptor do when stimulated? |
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Definition
The vessels dilate and blood flow increases. |
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Term
What stimulates the dopaminergic receptor? |
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Definition
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Term
What are the three categories of sympathomimetic drugs that stimulate adrenergic receptors? |
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Definition
direct acting sympathomimetics, indirect acting smpathomimetics and mixed acting sympathomimetics. |
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Term
What are examples of direct acting sympathomimetics. |
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Definition
epinephrine and norepinephrine |
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Term
What are examples of indirect acting sympathomimetics? |
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Definition
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Term
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Definition
they are either endogenous or synthetic that can produce a sympathomimetic response. |
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Term
Albuterol sulfate is selective for which receptor site? |
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Definition
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Term
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Definition
a pure bronchodilation response |
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Term
what receptor does clonidine and methyldopa act on? |
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Definition
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Term
what do clonidine and methyldopa mostly treat? |
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Definition
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Term
what do alpha 2 drugs regulate th release of? |
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Definition
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Term
What are the three sympatholytic receptors? |
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Definition
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Term
what do selective alpha blockers block? |
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Definition
the alpha 1 receptor site |
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Term
what do nonselective alpha blockers block? |
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Definition
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Term
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Definition
they decrease heart rate and decrease blood pressure |
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Term
what does bradycardia mean? |
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Definition
a slow pulse rate of 60 beats per minute or less. |
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