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Adrenergic Agonists
Miscellaneous
17
Pharmacology
Professional
07/21/2012

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Cards

Term
Amphetamine
Methamphetamine
Methylphenidate
Pemoline
Definition
stimulate central and sympathetic nervous system
cross BBB
Term
Amphetamine
Methamphetamine
Methylphenidate
Pemoline
Definition
addiction and withdrwawl possible
tolerance develops
Term
Amphetamine
Methamphetamine
Pemoline
Definition
increase release of all catecholamines
Term
Methylphenidate
Definition
blocks reuptake of dopamines at central synapses
Term
Amphetamine
Methamphetamine
Methylphenidate
Pemoline
Definition
alertness, euphoria, and self confidence
Term
Amphetamine
Methamphetamine
Methylphenidate
Pemoline
Definition
ADHD and Narcolepsy
Term
Amphetamine
Methamphetamine
Methylphenidate
Pemoline
Definition
do not give with MAOIs
will cause hypertensive crisis and death
Term
Ephedrine
Definition
increase catecholamine relase
directly activates A and B receptors
Term
Ephedrine
Definition
combats fall in BP (increase CO and PR)
nasal congestion relief
Term
Pseudoephedrine
Definition
decongestant
less potent
Term
Cocaine
Definition
blocks reuptake catecholamines
local anesthetic
Term
Cocaine
Definition
excess dopamine in the pleasure centers of the brain
can cause HTN/tachycardia due to potent peripheral sympathomimetic actions
Term
Tyramine
Definition
indirect activator in fermented food (cheese and wine).
avoid these food if taking MAOIs to avoid hypertensive crisis
Term
Amphetamine
Methamphetamine
Methylphenidate
Pemoline
Definition
in the periphery, increase systolic and diastolic pressure, leading to reflex reduction in heart rate
CO not enhanced
can cause arrhythmias
Term
Methylphenidate
Definition
particulary useful for tx ADHD due to its lack of peripheral cardiovascular effects
Term
Methamphetamine and Amphetamine
Definition
high doses cause disturbances of perception and psychotic behavior due to increased serotonin and dopamine releasein the mesolimbic system
Term
Ephedrine
Definition
more prolonged and less potent then epinephrine
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