Term
| Primary Hypoadrenocorticism |
|
Definition
destruction of the adrenal cortex due to immune mediated, infection, or neoplasia
causes lack of glucocorticoids and mineralocorticoids |
|
|
Term
| Secondary Hypoadrenocorticism |
|
Definition
decreased ACTH
long-term administration of corticosteroids
deficiency in glucocorticoids only |
|
|
Term
| Atypical Hypoadrenocorticism |
|
Definition
gradual destruction of adrenal tissue
deficiency in glucocorticoids only
mineralocorticoids are within normal limits |
|
|
Term
|
Definition
glucose metabolism and gluconeogenesis
immune system
inflammatory responses
health and integrity of the GI mucosa
stress tolerance |
|
|
Term
| Signs of Glucocorticoid Deficiency |
|
Definition
waxing-waning course to illness
exercise intolerance
gastrointestinal disturbances
weakness |
|
|
Term
| Roles of Mineralocorticoids |
|
Definition
aldosterone
water and electrolyte balance
release triggered by hypovolemia
promotes renal reabsorption of sodium and water
promotes renal excretion of potassium |
|
|
Term
| Signs of Mineralocorticoid Deficiency |
|
Definition
hyperkalemia
hyponatremia
hypovolemia
weakness
PU/PD
hypovolemic shock
cardiac arrhythmias |
|
|
