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Action Potential
Action Potential Generator and Propagade
35
Physiology
Undergraduate 2
03/17/2015

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Term
During resting potential, inside of the cell is about?
Definition
-70mV
Term
During the end of depolarization, inside of the cell is about
Definition
+35mV(105)
Term
The threshold for the action potential to fire is about
Definition
-55mV
Term
Inactivation gate is related to
Definition
Na+ Sodium channels
Term
The concentration of ___ is high outside of cell during resting potential
Definition
Na+
Term
Does Sodium Potassium pump need ATP? Yes or no
Definition
Yes
Term
Higher concentration of _____ on outside and lower concentration of _______ inside
Definition
Na outside, sodium inside
Term
Inside is ______ charged and outside is ______ charged.
Definition
inside negatively, postively outside.
Term
What are the 3 reasons for the cause of inside being negative
Definition
1. protein molecules inside of cells are negatively charged, proteins cant get out its too big. 2. sodium potassium pump, pumping 3 positive out and bringing 2 positive in. More positive ions outside. 3. Leak channels(faciliated diffusion) , more potassium leak channels then sodium. Sodium goes in but sodium potassium pump out.
Term
Which channel can be found majority on the axon hillock?
Definition
sodium voltage sensitive channels
Term
sodium gates have 2 doors, which is _____ on the outside and inside is _____
Definition
Activation on the outside, inactivation on the inside
Term
There are also potassium sensitive voltage channels. True or false?
Definition
True
Term
Concentration gradients exist across the plasma membrane. Specifically, there are ________.
Definition
more potassium ions inside and more sodium ions outside the plasma membrane
Term
The value of the resting membrane potential is ________.
Definition
-70 mV
Term
The plasma membrane is more permeable to ________.
Definition
potassium ions
Term
The resting membrane potential depends on each item below, EXCEPT:
Definition
the greater permeability of the membrane to anions rather than cations.
Term
The Na+/K+ pump transports ________.
Definition
Na+ out of and K+ into the cell
Term
If potassium was the only ion moving out
Definition
it would be the -90mV
Term
sodium gates have 2 doors, which is _____ on the outside and inside is _____
Definition
Activation on the outside, inactivation on the inside
Term
When does inside of the neuron become positive?
Definition
During depolirazation
Term
The action potential is initiated in the ________.
Definition
initial segment
Term
A threshold stimulus immediately ________
Definition
opens voltage gated sodium channels
Term
Phase 2 of the action potential is known as
Definition
repolarization
Term
The membrane potential returns to the resting state due to ________
Definition
the diffusion of ions through leak channels.
Term
he influx of sodium ions in one segment of an unmyelinated axon initiates the following events, EXCEPT ________
Definition
.a repolarizing current that brings the adjacent segment to threshold
Term
The lighting effect at the arrow below denotes
Definition
action potential
Term
what is it called when there is nothing happening?
Definition
resting potential
Term
which gates does a -55mv fire open up
Definition
activation gate on the voltage sodium sensitive channel
Term
why doesnt sodium go out when the activation gate opens?
Definition
because it goes from high to low concentration
Term
what are the 2 reasons sodium goes in?
Definition
higher concentratiou outside as suppose to inside. 2. outside is positive and inside negative and they attract eachother.
Term
what are the ions togheter called?
Definition
electro chemical gradient
Term
what is another term when sodium rushes in during depolorization?
Definition
sodium influx
Term
when does potassium voltage sensitive channels start opening up?
Definition
when there is a positive 35 mv fire
Term
when is repolirization?
Definition
when the potassium is leaving
Term
as potassium leaves
Definition
inactivation gates close temporarily
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