Term
| Hemostasis is a balance of which three processes? |
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Definition
-Thrombotic
-Anticoagulant
-Fibrinolytic |
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Term
| Where do the extrinisic and intrinsic coagulation pathways meet? |
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Definition
| Both pathways lead to the activation of factor Xa, the conversion of prothrombin into thrombin and conversion of fibrinogen to the insoluble fibrin thread that hold a clot together |
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Term
|
Definition
-Requires injury to vessel wall for activation
-requires a surface for activation
-shorter and faster |
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|
Term
|
Definition
-Has more steps
-Takes longer to get going
-Does not require a surface to initiate the process |
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Term
|
Definition
-Give 10-15mL/kg to completely reverse someone related to coumadin
-give 30-45 minutes before OR |
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Term
|
Definition
| 1 unit increased hgb by 1gm, increases hematocrit by 3-4% |
|
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Term
| Which clotting factors are replaced with FFP? |
|
Definition
| Vitamin K factors-II, VII, IX, X |
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Term
| Under which circumstances should FFP be given? |
|
Definition
-Reverse supratheraputic INR
-reverse therapeutic INR before emergency surgery
-coagulation disorders related to liver disease
-isolated factor issue |
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|
Term
| Under which circumstances are platelets given |
|
Definition
-thrombocytopenia: quantitative platelet count <20,000
-qualitative problem-no working circulating platelets |
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|
Term
|
Definition
-1 unit has 5 or 6 packs
-goal is raise platelet count 20-60 thousand
-if refractory to platement replacement, give single donor replacment
-platelets last 1-7 days after transfusion |
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|
Term
| Under which circumstances is cryoprecipate given? |
|
Definition
-Indicated in low fibrinogen levels <100 in patient that is actively bleeding
-pt may be in DIC or severe sepsis |
|
|
Term
|
Definition
-7-10ml/kg
-dose is 1 unit
-each pool of 10 units=2000 units of fibrinogen |
|
|
Term
|
Definition
-large, low molecular protein given to treat conditions associated hyponatremia
-can be given to increase osmotic pressure to pool fluid from he interstitial space to the intravascular space, increasing circulating blood volume |
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Term
|
Definition
| -May be used as first line before you go to albumin |
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Term
| How much blood does a fully soaked 4x4 hold |
|
Definition
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Term
| How much blood does a fully soaked lap pad hold? |
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Definition
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