Term
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Definition
| MOA: Slows conduction time through AV node
AR: Facial flushing, SOB, chest pain, headache, paresthesia, diaphoresis, paplpitations, hypotension, nausea, metallic taste |
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Term
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Definition
| MOA: Noncompetitive alpha and beta sympathetic blocking, Calcium channel blocking
AR: Hypotension, bradycardia, PEA, CHF, nausea, fever, abnormal liver function tests, thrombocytopenia |
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Term
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Definition
| MOA: prostaglandin inhibition
AR: heartburn, GI bleeding, nausea, vomiting, wheezing in allergic pt, prolonged bleeding |
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Term
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Definition
| MOA: parasympatholitic, increases heart rate in life threatening bradydystrhythmias
AR: Headache, dizziness, palpitations, nausea and vomiting, tachycardia, dysrhythmias, anticholinergic effects, paradoxical bradycardia at low doses, flushed hot, dry skin |
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Term
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Definition
| MOA: Increases cardiac contractile state (positive inotrope), may enhance ventricular automaticity
AR: Bradycardia, asystole, hypotension, peripheral vasodilation, metallic taste, local necrosis, coronary and cerebral artery spasm, nausea, vomiting |
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Term
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Definition
| MOA: Blocks influx of calcium ions into cardia muscle, prevents spasm of coronary arteries, reduces preload and afterload, reduces myocardial oxygen demand
AR: Bradycardia, 2nd or 3rd degree blocks, chest pain, CHF, syncope, VFib, VTach, mausea, voiting, dizziness, dry mouth, dyspnea, headache |
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Term
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Definition
| MOA: Immediate precursor to norepinephrine, increases systemic vascular resistance, dilates renal vasculature, increases myocardial contractility and stroke volume
AR: Cardiac dysrhythmias, hypertension, increased myocardial O(2) demand, extravasation causes tissue necrosis |
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Term
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Definition
| MOA: Direct acting alpha and beta agonist, blocks histamine release
AR: Hypertension, dysrhythmias, pulmonary edema, anxiety, psychomotor agitation, nausea, angina, headache, restlessness |
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Term
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Definition
| MOA: Inhibits electrolyte reabsorbtion and promotes excretion of sodium, potassium and chloride
AR: Hypovolemia, hypokalemia, ECG changes, dry mouth, hypochloremia, hyponatremia, hyperglycemia (due to hemoconcentration) |
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Term
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Definition
| MOA: Decreases automaticity by slowing the rate of spontaneous Phase 4 depolarization
AR: slurred speech, seizures, altered mental status, confusion, lightheadedness, blurred vision, bradycardia |
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Term
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Definition
| MOA: Reduces acetylcholinesterase release at the myoneural junction, induces uterine relaxation
AR: Respiratory and CNS depression, hypotension, cardiac arrest, asystole, facial flushing, diaphoresis, depressed reflexes, circulatory collapse |
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Term
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Definition
| MOA: Selective inhibitor of beta1-adrenergic, completely blocks beta1, no effect on beta2 at doses <100mg
AR: Bronchospasm, bradycardia, palpitations, edema, CHF, reduced peripheral circulation, drowsiness, insomnia |
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Term
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Definition
| MOA: Anxiolytic and sedative properties similar to other benxodiazepines, memory impairment
AR: Hiccough, cough, oversedation, nausea, vomiting, injection site pain, headache, blurred vision, hypotension, respiratory depression and arrest |
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Term
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Definition
| MOA: alleviates pain through CNS actions, suppresses fear and anxiety centers in brain, depresses brain stem respiratory centers, decreases preload and afterload, decreases myocardial O(2) needs
AR: Respiratory depression, hypotension, decreased LOC, mausea vomiting, bradychardia, tachycardia, syncope, facial flushing, euphoria, bronchospasm, dry mouth |
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Term
| nitroglycerin or nitropaste |
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Definition
| MOA: Smooth muscle relaxant acting on vascular, bronchial, uterine and intestinal smooth muscle
AR: Headache, hypotension, syncope, reflex tachycardia, flushing, nausea, vomiting, diaphoresis, muscle twitching |
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Term
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Definition
| MOA: Facilitates metabolism necessary for life
AR: Retrolental fibroplasia in premature infants |
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Term
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Definition
| MOA: Suppresses Phase 4 depolarization in normal ventricular muscle and Purkinje fibers, reducing automaticity of ectopic pacemakers, suppresses reentry dysrhythmias by slowing intraventricular conductions
AR: PR, QRS, QT widening, AV block, cardiac arrest, hypotension, seizures, nausea, vomiting, reflex tachycardia, PVC's VT, VF |
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Term
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Definition
| MOA: Reacts with hydrogen ions to form water and carbon dioxide thereby acting as a buffer for metabolic acidosis
AR: Metabolic alkalosis, hypokalemia, hyperosmolarity, fluid overload, increase in tissue acidosis, electrolyte imbalance, seizures, tissue sloughing at injection site |
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