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substance that can absorb excess H+ (acid) or OH- (base) |
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proteins (- charge), such as Hgb, can bind with H+ (fast) phosphate (PO4-) can bind with H+ cellular ion exchange- can interchange H+ with K+ |
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Respiratory System as Buffer |
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Definition
(minutes to hours) lungs regulate retention or elimination of CO2 thru changes in rate of ventilation |
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Definition
(hours to days) kidneys reabsorb more HCO3- or H+ excrete more HCO3- or H+ |
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decreased pH of arterial blood (<7.35) systemic increase in H+ concentration or decrease in HCO3- |
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increased pH of arterial blood (>7.45) systemic decrease in H+ concentration or increase in HCO3- |
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Respiratory Acidosis Etio |
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Definition
anything depressing ventilation or gas exchange depression of respiratory center, resp muscle disorder, lung disorders |
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Respiratory Acidosis Initial ABGs |
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Definition
pH=low pCO2=high HCO3=normal |
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Respiratory Acidosis Compensation |
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Definition
by the kidneys- retain more HCO3 or excrete more H+ |
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Respiratory Acidosis Compensated ABGs |
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Definition
pH= low side of normal pCO2= high HCO3= high (bring more base in --> increased HCO3) |
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Respiratory Alkalosis Etio |
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Definition
hyperventilation (blow off more CO2) panic attack, ventilator |
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Respiratory Alkalosis Initial ABGs |
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Definition
ph=high pCO2=low (blown off CO2) HCO3=normal |
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Respiratory Alkalosis Compensation |
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Definition
by the kidneys excrete more HCO3- or retain more H+ |
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Respiratory Alkalosis Compensated ABGs |
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Definition
pH=high side of normal pCO2=low HCO3=low |
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Definition
loss of base (HCO3-) or gain of acid (H+) renal failure (kidneys unable to retain HCO3-) lactic acidosis (muscle breakdown) DB ketoacidosis (buildup of ketone acids) diarrhea (lose intestinal HCO3-) ingestion of acids (chemicals) |
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Metabolic Acidosis Initial ABGs |
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Definition
pH=low pCO2=normal HCO3=low (loss of HCO3- or gain of H+) |
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Metabolic Acidosis Compensation |
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Definition
by the lungs hyperventilate to get rid of CO2 |
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Metabolic Acidosis Compensated ABGs |
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Definition
pH=low side of normal pCO2=low HCO3=low |
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Definition
loss of metabolic acids (prolonged vomiting), excess HCO3- intake (accidental poisoning) |
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Metabolic Alkalosis Initial ABGs |
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Definition
pH=high pCO2=normal HCO3=high |
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Metabolic Alkalosis Compensation |
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Definition
by the lungs hypoventilate to retain more CO2 |
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Metabolic Alkalosis Compensated ABGs |
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Definition
pH=high side of normal pCO2=high HCO3=high |
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