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Acid-Base Disturbances
PATHO
29
Other
Professional
10/05/2011

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Term
Responsible for maintaining H near normal levels despite daily acidic/alkaline loads from intake and metabolism of food
Definition
Homeostasis
Term
What organ controls serum bicarbonate concentration through excretion or absorption?
Definition
Kidneys
Term
What organ controls CO2 concentrations through changes in the depth/and or rate of respiration
Definition
Lungs
Term
What percentage of H+ do kidneys excrete daily?
Definition
Less than 1
Term
What is HCO3 regulated by?
Definition
Renal metabolism via enzyme carbonic anhydrase
Term
What three things does arterial blood gas (ABG) measure?
Definition
pH, PaCO2, HCO3
Term
Term for abnormally low arterial blood pH (less than 7.35)
Definition
Acidema
Term
Pathological process that acidifies body fluids
Definition
Acidosis
Term
Term for abnormally high arterial blood pH (More than 7.45)
Definition
Alkalemia
Term
Pathological process that alkalinizes body fluids
Definition
Alkalosis
Term
Which disorder is caused by a respiratory insufficiency resulting in an increased CO2 concentration?
Definition
Respiratory acidosis
Term
Increasing serum HCO3 is compensation for which disorder?
Definition
Respiratory acidosis
Term
Which disorder is caused by hyperventilation resulting in a decreased CO2 concentration?
Definition
Respiratory alkalosis
Term
Decreasing serum HCO3 is the compensation for which disorder?
Definition
Respiratory alkalosis
Term
Which disorder do you primarily see a decrease in serum HCO3?
Definition
Metabolic acidosis
Term
Increasing ventilation with a decrease in arterial CO2 is compensation for which disorder?
Definition
Metabolic acidosis
Term
Which disorder is characterized by an increase in serum HCO3?
Definition
Metabolic alkalosis
Term
Decreasing ventilation with an increase in CO2 is compensation for which disorder?
Definition
Metabolic alkalosis
Term
T/F: Acid base disturbances are always manifestations of underlying clinical disorders.
Definition
True
Term
Loss in what increases the anion gap?
Definition
Serum HCO3
Term
If the anion gap is greater than 12 mEq/L, which disease state is this?
Definition
Metabolic acidosis
Term
Term where calculated anion gap exceeds normal anion gap?
Definition
Excess gap
Term
Which calculation represents the amount of HCO3 lost due to buffering unmeasured cations?
Definition
Excess gap
Term
4 important steps in determining patient's acid/base disorder (chart in book)
Definition
1) Inspection of pH, PaCO3, HCO3
2) Assessment of compensation
3) Calculate anion gap
4) Calculate excess gap
Term
Supportive treatment of the pH and electrolytes is often needed until the underlying metabolic disease state is improved.
Definition
True
Term
Lactic acidosis and ketoacidosis can be results of which disease state?
Definition
Metabolic acidosis
Term
Symptoms such as changes in cardiovascular, musculoskeletal, neurologic, pulmonary functioning result from which disorder
Definition
Metabolic acidosis
Term
NaHCO3 is a common treatment for which acid/base disorder?
Definition
Metabolic acidosis
Term
Headache, blurred vision, restlessness, anxiety, tremors are symptoms for which disorder?
Definition
Respiratory acidosis
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