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Acc. Biology Genetics 2
Simon Kenton
68
Biology
10th Grade
03/11/2012

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Term
DNA
Definition
Deoxyribonucleic acid
Term
The backbone of DNA is...
Definition

deoxyribose

phosphate

Term
Nucleotide
Definition

deoxyribose

phosphate

nitrogen base

Term
4 Nitrogen Bases in DNA
Definition

adenine

guanine

cytosine

thymine

Term
Purine
Definition

double ring

Ex: adenine and guanine

Term
Pyrimidine
Definition

single ring

Ex: cytosine and thymine

Term
What is the sugar in DNA?
Definition
deoxyribose
Term
The amount of adenine equals the amount of
Definition
thymine
Term
The amount of cytosine equals the amount of
Definition
guanine
Term
The two strands of DNA are ____ to each other
Definition
complementary
Term
What is meant by complementary base pairing?
Definition

A and T bond together

C and G bond together

Term
DNA is a ____ stranded molecule in the shape of a double _____.
Definition

double

helix

Term
How can organisms be so different from each other if their genetic material is made of the same four nucleotides?
Definition
Differences in organisms are from the sequence of bases and the order of the bases
Term
Replication
Definition
DNA is copied
Term
What is the name of the enzyme that unzips the DNA in replication?
Definition
DNA helicase
Term
What is the name of the enzyme that glues on the nucleotides during replication?
Definition
DNA polymerase
Term
At the end of replication the 2 molecules of DNA are ____ to each other.
Definition
identical
Term
Where does DNA replication take place?
Definition
nucleus
Term
In what direction does DNA polymerase move?
Definition
3' to 5'
Term
The strand that runs 3'-5' in the same direction it is unzipping is the ____ strand
Definition
leading
Term
The strand that runs 3'-5' in the opposite direction that it is unzipping is the ____ strand.
Definition
lagging
Term
Okazaki Segments
Definition
short segments of complementary DNA
Term
Lagging strand
Definition
  • New strand is replicated in the opposite direction it is unzipping.
  • Takes more time to assemble
  • Creates Okazaki segements
Term
What is the name of the enzyme that joins together the Okazaki segments?
Definition
DNA ligase
Term
Leading Strand
Definition
  • Strand assembled in the same direction it is unzipping.
  • Assembles fast 
Term
RNA
Definition
ribonucleic acid
Term
The sugar in RNA is...
Definition
ribose
Term
The nitrogen bases in RNA are...
Definition
adenine, cytosine, guanine and uracil
Term
RNA is a ____ stranded molecule
Definition
single
Term
Transcription occurs in the..
Definition
nucleus
Term
mRNA
Definition
  • messenger RNA
  • takes information from the DNA in the nucleus to ribosome
Term
tRNA
Definition
  • transfer RNA
  • transports amino acids to the ribosome 
Term
rRNA
Definition
  • ribosomal RNA
  • what ribosomes are made of 
Term
Transcription
Definition

Make an RNA copy of a portion of a DNA strand

Term
What is the name of the enzyme that unzips the DNA in transcription?
Definition
RNA polymerase
Term
What is the name of the enzyme that glues on the nucleotides in transcription?
Definition
RNA polymerase
Term
What is made at the end of transcription?
Definition
A single strand of RNA
Term
Codon
Definition
a set of 3 nitrogen bases that represents an amino acid
Term
There are how many different types of amino acids
Definition
20
Term
There are how many possible combinations for codons
Definition
64
Term
How many codons code for amino acids
Definition
61
Term
What are the stop codons
Definition
UAA, UGA, UAG
Term
What is the start codon and what does it code for.
Definition
AUG and codes for methionine
Term
A chain of amino acids makes a
Definition
protein
Term
Translation
Definition
The process of converting mRNA into a sequence of amino acids
Term
Where does translation take place
Definition
ribosome
Term
Anti-codon
Definition
is carried on the tRNA and attaches to the codon
Term
Mutation
Definition
any change in a DNA sequence
Term
2 Types of Mutations
Definition
DNA and Chromosomal
Term
2 types of DNA mutations
Definition
Point and Frameshift
Term
Point Mutation
Definition
a change in a single base pair in DNA
Term
Frameshift Mutation
Definition

a single base is added or deleted from DNA and causes every amino acid from that point on to change

Term
Chromosomal Mutation
Definition
changes in chromosomes during replication
Term
Chromosomal mutations are rarely passed on to the next generation because...
Definition
  • the zygote usually dies
  • the mature organism is usually sterile 
Term
4 Types of Chromosomal Mutations
Definition

deletion

duplication

inversion

translocation

Term
Deletion
Definition

a fragment of a chromosome breaks off, and is lost

Term
Duplication
Definition
a chromosome fragment attaches to its homologous chromosome, which will then carry two copies of a gene
Term
Inversion
Definition
Fragment reattaches to the original chromosome in the reverse orientation
Term
Translocation
Definition

a fragment may join a nonhomologous chromosome

Term
Spontaneous Mutations
Definition
a mistake in base pairing during DNA replication.  It occurs at random
Term
Mutagen
Definition
any agent that can cause a change in DNA
Term
Proofreading Enzymes
Definition
reads the DNA strand and checks it for mistakes
Term
Repair Enzymes
Definition
Fixes any mistakes in the DNA strand
Term
Nondisjunction
Definition
failure of homologous chromosomes to separate
Term
Trisomy
Definition

1 extra chromosome

Ex: down syndrome

Term
Tetraploid
Definition
2 extra chromosomes
Term
Monosomy
Definition

missing 1 chromosome

Ex: turner syndrome

Term
Polyploids
Definition
organisms with more than the two chromosome per set.
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