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Major Depression; dsythymia |
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Criteria Sets for mood disorders require the presence (or absence) of mood disorders: |
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Major Depressive Episode; Manic Episode, Hypomanic episode |
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prominent physiological symptoms |
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delusions and hallucinations |
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lack of movement, disturbances in speech |
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assortment of odd symptoms |
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within 4 weeks of delivery of child |
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seasonal affective disorder |
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a less severe, more chronic unipolar depression |
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women are about 2x as likely as men to experience mild and severe depression |
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women are about 2x as likely as men to experience mild and severe depression |
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a category of mood disorders on Axis I, DSM-IV-TR that includes major depression and dysthymia |
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Definition
a category of mood disorders on Axis I, DSM-IV-TR that includes major depression and dysthymia |
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a terms for being diagnosed with both major depression and dysthymia |
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how are mood disorders categorized either unipolar or bipolar? |
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based on the presence or absence of mood episodes |
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unipolar disorders involve: |
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major depressive episodes and NO manic, mixed or hypomanic |
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Bipolar disorders include: |
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major depressive episodes, manic episodes, hypomanic episodes |
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bipolar disorders include: |
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manic, hypomanic and mixed episodes |
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less severe manic episodes |
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Bipolar I includes ____ vs Bipolar II does not |
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Definition
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______ is to unipolar depression as _______ is to bipolar depression |
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Dysthymia; cyclothymic disorder |
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men and women are equally likely to be diagnosed with ___________. |
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Monoamines in the limbic system: |
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Definition
serotonin, norepinephrine, dopamine |
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Definition
-travels all over the brain... doing everything & nothing -regulates emotion -genes related to 5-ht identified in several illnesses |
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Norepinephrine (noradrenaline) |
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Definition
-produced by neurons in the brain stem -cocaine & amphetamines prolong the action of norepinephirne by slowing its reuptake |
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Definition
-affects reward systems in the brain -important to functioning of muscle systems -lack of DA identified in parkinsons disease |
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Depression caused by reduction of monoamines in the synapses -decreased synthesis -increased degredation by synaptic enzyme -impaired release or reuptake |
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what is the hypothalamic-pituitary-adrenal axis or HPA axis? |
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the main hormone biofeedback system connected to the limbic system |
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electroconvulsive therapy (ECT) |
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Definition
-given to patients who do not respond to medication -relieves depression in 50-60%, but 85% relapse |
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Vagus Nerve Stimulation (VNS) |
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Definition
vagus nerve- part of the autonomic nervous system carries information from the head, neck, thorax and abdomen to the brain |
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Repetitve Transcranial magnetic stimulation (rTMS) |
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Definition
-electrical stimulation repeated, high-intensity magnetic impulses of neurons affect neurotransmitter release -few side effects -patiets remain awake (unlike ECT) |
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tricyclic antridepressants |
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Definition
reduce reuptake of norepinephrine & serotonin by changing responsiveness of receptors |
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tricyclic antidepressants problems |
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Definition
-bad side effects -takes 3-4 weeks to work -fatal overdoes of only 3-4x prescribed |
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monoamine oxidace inhibitors (MAOIs) |
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-is a synaptic enxyme -increase synaptic neurotransmitter levels by decreasing enzyme action |
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-fatal interatcion: tyramine, antihypertense & antihistamine meds -cause liver damage, weight gain, etc. |
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Selective Serotonin Reuptake Inhibitors (SSRIs) |
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prevent reuptake of serotonin in the synapse |
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-less severe side effects -relief within a couple of weeks -not fatal in overdoes |
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