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A&P
nervous systems
128
Biology
Undergraduate 1
11/16/2011

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Term
Afferent Nerves
Definition
sensory nerves that convey info from PNS to CNS from sensory receptors in body
Term
Efferent Nerves
Definition
motor nerves that transmit impulses from the CNS to PNS to muscles and glands
Term
Sympathetic
Definition
excitatory/stimulatory response
Term
Parasympathetic
Definition
inhibitory response
Term
Anterograde movement
Definition
movement of an impulse to the axon terminal
Term
Retrograde movement
Definition
movement of an impulse to the cell body RARE
Term
Neuroglia
Definition
any cell other than a neuron in the nervous system
Term
Astrocytes
Definition
star shaped; form a seal for capillaries in CNS; form scar tissue
Term
Microglia
Definition
phagocytes in CNS; involved in inflammation and repair
Term
Ependymal cells
Definition
ciliated, line cavities of brain and spinal cord, absorb and release CSF
Term
Oligodendrocytes
Definition
form myelin sheaths in CNS axons
Term
Schwann cells
Definition
form myelin sheaths in PNS axons
Term
satellite cells
Definition
provide metabolic support for neurons in pns
Term
gliomas
Definition
primary cns tumor; arises from glial cells; can affect spinal cord, brain, or optic nerves
Term
nuclei
Definition
clusters of cell bodies in the CNS
Term
ganglia
Definition
clusters of cell bodies in the PNS
Term
tracts
Definition
bundles of neuron processes in the CNS
Term
nerves
Definition
bundles of neuron processes in the PNS
Term
white matter
Definition
meylinated fibers; central in the brain, peripheral in the spinal cord
Term
gray matter
Definition
unmyelinated fibers and cell bodies; peripheral in the brain, central in the spinal cord
Term
multipolar
Definition
multiple dendrites, single axon
Term
bipolar
Definition
one fused dendrite, one axon
Term
unipolar
Definition
one process extends from cell body and splits into an axon with a receptive region or end and a secretory region or end
Term
stimulus
Definition
a change in environment
Term
integration
Definition
processing and interpreting
Term
motor output
Definition
a response to a stimulus
Term
chemically gated channel
Definition
open when a neurotransmitter binds to channel; typically in dendrite region
Term
voltage gated channel
Definition
open in response to a nearby flow of ions; open in response to one b4 opening; change in membrane potential--->depolarization; membrane is polarized when resting; typically along cell body/axon
Term
saltatory conduction
Definition
signal propagation in an axon thats myelinated. impulse jumps from node to node. allows impulse to travel quicker
Term
multiple sclerosis
Definition
autoimmune degeneration of the myelin sheath of neurons in the cns; no myelin-->interferes with the signal propagation-->numbness, weakness, pain, memory probs
Term
synapse
Definition
one axon to another neuron, muscle, or gland
Term
chemical synapse
Definition
connection btwn neuron and its target; neurotransmitter is released into synaptic cleft and taken up by target
Term
electrical synapse
Definition
protein channels found in the cell membranes of adjacent neurons connect the neurons allowing ions to flow directly from one straight into the other; common in embryos
Term
neuronal pools
Definition
groups of neurons that process and integrate info
Term
diverging circuit
Definition
one neuron triggers many others; amplification of signal
Term
converging circuit
Definition
many neurons converge onto one neuron; concentration of signal
Term
reverberating circuit
Definition
some neurons of a group reconnect with others; continuous output signal
Term
parallel after discharge circuit
Definition
one incoming neuron stimulates several neurons which stimulate the final neuron at different times; thought to be involved in complex mental tasks; diverging and converging in one
Term
serial processing
Definition
asslemby line stimulation
Term
parallel processing
Definition
input signals branch into different areas
Term
reflex
Definition
rapid, automatic, involuntary response
Term
neuroblastoma
Definition
a malignant tumor of embryonic neurons
Term
neurotoxin
Definition
compound that destroys nervous tissue
Term
gyri
Definition
elevated ridges of tissue
Term
sulci
Definition
shallow grooves
Term
fissures
Definition
deeper grooves that separate large regions of the brain
Term
ventricles
Definition
central cavities within the brain and spinal cord where CSF flows
Term
meninges
Definition
3 layers: dura mater, arachnoid mater, subarachnoid mater
Term
hydrocephalus
Definition
build up of CSF due to obstruction of CSF drainage
Term
concussion
Definition
unconsciousness from blow to head
Term
subdural hemorrage
Definition
bleeding from ruptured vessels into spaces; may result in death. blood puts pressure on brain pushing brain stem thru foramen magnum
Term
cerebral edema
Definition
swelling of the brain following traumatic head injury
Term
encephalitis
Definition
inflammation of the brain
Term
coma
Definition
total unresponsiveness to sesnory stimuli for an extended period
Term
CVA
Definition
cerebrovascular accidents; strokes
Term
stroke
Definition
when blood circ to a brain area is blocked and brain tissue dies
Term
TIA
Definition
transient ischemic attack; blood flow to part of brain stops. stroke like symptoms
Term
poliomyelitis
Definition
destruction of grey matter, specifically the anterior horn motor neurons, caused by polio virus, fever, headache, weakness-->paralysis
Term
tabes doralis
Definition
slowly progressive condition caused by deterioration of gracilis and cuneatus, late sign of syphilis
Term
parathesia
Definition
abnormal sensation resulting from sesnory nerve disorder, burning, numbness, tingling
Term
flaccid paralysis
Definition
severe damage to ventral root or anterior horn cells, skeletal muscles cannot move voluntarily or involuntarily
Term
spastic paralysis
Definition
when only the upper motor neurons of the primary motor cortex are damaged. spinal motor neurons remain intacts, muscles continue to be stimulated irregularly.
Term
paraplegia
Definition
injury in thoracic, lumbar, or sacral region
Term
quadraplegia
Definition
injury in cervical/neck area
Term
myelitis
Definition
inflammation of spinal cord
Term
amyotrophic lateral sclerosis
Definition
ALS. progressive destruction of anterior horn motor neurons
Term
cordotomy
Definition
tract removal in the spinal cord due to unremitting pain
Term
exteroreceptors
Definition
respond to stimuli from outside of the body
Term
interoreceptors
Definition
respond to stimuli from within the body
Term
proprioreceptors
Definition
detect position, stretch, and movement
Term
mechanoreceptors
Definition
detect temperature change
Term
chemoreceptors
Definition
detect molecules in solution that are smelled or tasted
Term
nocireceptors
Definition
detect pain
Term
free nerve endings
Definition
unmyelinated, found everywhere, detect pain and temp
Term
meissner's corpuscles
Definition
found high in dermis, especially in hairless areas; light touch receptors
Term
krause end bulbs
Definition
modified meissners found specically in mucosa
Term
pacinian corpuscles
Definition
found deep in dermis and hypodermis, detect deep pressure initiation
Term
ruffini's corpuscles
Definition
found deep in dermis and hypodermis, detect deep continuous pressure
Term
muscle spindles
Definition
proprioceptors found in the perimysium of skeletal muscles, detect when a muscle is stretched
Term
golgi tendon organs
Definition
proprioceptors in tendons, close to skeletal muscle insertions, stimulated when muscle contracts and stretches tendon
Term
joint kinesthetic receptors
Definition
proprioceptors that monitor stretch in the capsules of synovial joints, provide info on joint position and movement
Term
adaptation
Definition
exhibited by hearing, smell, and some sensory receptors, a reduction in sensitivity in the presence of constant stimulus
Term
phasic receptors
Definition
normally off unless activated by some change in the environment
Term
tonic receptors
Definition
receptors that generate nerve impulses at a constant rate unless inhibited or activated to a greater degree
Term
endoneurium
Definition
loose CT that encloses each axon's myelin sheath
Term
perineurium
Definition
coarse CT that surrounds each fascicle of nerve fibers
Term
epineurium
Definition
tough fibrous sheath surrounding a cluster of fasicles
Term
mixed nerved
Definition
nerves that contain both sensory and motor fibers thereby transmitting impulses to and from the CNS
Term
nerve plexus
Definition
interlacing nerve networks that ocur in all regions of the spine
Term
phrenic
Definition
supplies diaphragm, part of cervical plexus
Term
median
Definition
part of brachial plexus, innervates palm, pronates forearm, flexes wrist and fingers
Term
ulnar
Definition
part of ulnar plexus, wrist and finger flexion
Term
radial
Definition
largest nerve of brachial plexus, innervates extensors of the upper limb
Term
sciatic
Definition
largest nerve from the sacral plexus, thickest/longest nerve in the body, innervates entire leg
Term
reflex arc
Definition
receptor, sensory neuron, CNS, motor neuron, effector muscle or gland
Term
neuralgia
Definition
pain in a nerve, sharp spasms, due to inflammation of injury
Term
sciatica
Definition
injury to the proximal portion of the sciatic nerve, characterized by stabbing pain radiating down the leg, leg is useless if nerve is cut
Term
dermatome
Definition
area of skin supplied by spinal nerve
Term
plantar reflex
Definition
tests the integrity of the spinal cord from l4-s2, draw object down foot
Term
babinski's sign
Definition
abnormal plantar reflex; great toe dorsiflex and small ones fan out
Term
neurofibromatosis
Definition
genetic defect where tumors form in connective tissue of nerves
Term
shingles
Definition
herpes zoster, chickenpox, infection of dorsal roots, skin lesions along dermatomes
Term
hilton's law
Definition
any nerve serving a muscle that produces movement at a join also innervates the joint and skin over the joint
Term
neostigmine
Definition
medication used to treat myasthenia gravis, inhibits breakdown of AcH
Term
(tricyclic) antidepressants
Definition
medication that prolongs norepinephrine activity
Term
beta blockers
Definition
medication that attatches to beta receptors in cardiac muscle thereby reducing heart rate and preventing arrhythmias
Term
hypertension
Definition
high BP due to overactive sympathetic vasoconstrictor response promoted by high lvls of stress
Term
raynaud's disease
Definition
intermittent attacks causing the skin of fingers and toes to turn pale, blueish, provoked by exposure to cold or stress
Term
synergy
Definition
coordination of skeletal muscles by the cerebellum
Term
ataxia
Definition
inaccurate jerky movements, disruption of synergy
Term
parkinson's
Definition
degeneration of dopamine producing neurons in brain stem, tremors, lack of facial expression
Term
huntington's disease
Definition
inherited disorder, progressive degeneration of basal nuclei and cerebrum, jerky movements, mental deterioration
Term
EEG
Definition
electroencephalogram, electrical measurement of brain waves
Term
epilepsy
Definition
uncontrollable seizures caused by abnormal electrical discharged from the brain
Term
petit mal seizure
Definition
mild seizure similar to daydreaming, occurs mostly in children, caused by depressed hypothalamus/thalmus brain waves
Term
grand mal seizures
Definition
very rapid brain waves cause convulsions and unconsciousness
Term
aura
Definition
a sensory hallucination that occurs before some grand mal seizures
Term
suprachiasmatic nucleus
Definition
a biological clock in hypothalamus that helps regulate sleep
Term
NREM sleep
Definition
non rapid eye movement. stage 1: eyes closed, body relaxes, vital signs, and eeg normal. 2: eeg becomes irregular 3: thetat and delta waves appear, vital signs slow. 4: delta waves predominate, vital signs very slow.
Term
REM sleep
Definition
rapid eye movement,brain waves become more active, dreaming occurs
Term
narcolepsy
Definition
involuntary lapses into sleep
Term
insomnia
Definition
chronic inability to obtain enough quality sleep
Term
fact memory
Definition
learned and forgotten qucikly, usually requires a very conscious effot
Term
skill memory
Definition
accquired thru practice, not easily forgotten, usually not as much conscious effort
Term
anterograde amnesia
Definition
cuased by damage to hippocampus and amygdala, no new memories can be formed
Term
retregrade amnesia
Definition
loss of past memories, what is lost depends on where brain damage is
Term
myoclonus
Definition
fleeting muscle contraction, often while falling alseep, due to fleeting activation of the RAS
Term
phantom pain
Definition
paint in an amputated limb due to sensory neurons firing
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