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Produced by the thyroid gland - the single most important hormone influencing the rate of cellular metabolism and body heat production |
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Acts with the nervous system to coordinate and integrate the activity of the body's cells Employs hormones |
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Chemical messengers which are produced by epithelial cells and released into the blood to be transported throughout the body |
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Organs that respond to a particular hormone |
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consists of 2 lobes - the anterior pituitary (adenohypophysis) and the posterior pituitary (neurohypophysis) Attached to the hypothalamus by the infundibulum |
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"Master endocrine gland," controlled by releasing or inhibiting hormones from the ventral hypothalamus Secretes 4 tropic hormones -Gonadotropins (follicle-stimulating hormone and luteinizing hormone) -adrenocorticotropic hormone (ACTH) -thryoid-stimulating hormone (TSH or thyrotropin)
Other important hormones (not directly involved the regulation of other endocrine glands) -growth hormone (GH) -prolactin |
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Hypophyseal portal system |
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Consists of the primary capillary plexus, hypophyseal portal veins, and secondary capillary plexus, leading releasing or inhibiting hormones from the ventral hypothalamus to the anterior pituitary lobe |
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Follicle-stimulating hormone and Luteinizing hormone |
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Gonadotropins secreted by the anterior pituitary lobe Regulate gamete production and hormonal activity of the ovaries and testes |
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Adrenocorticotropic hormone |
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Secreted by the anterior pituitary lobe Regulates the endocrine activity of the adrenal cortex |
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Thyroid-stimulating hormone |
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Secreted by the anterior pituitary lobe Influences the growth and activity of the thyroid gland |
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Secreted by the anterior pituitary lobe A general metabolic hormone that helps determine body size - growth of muscle and long bones Hyposecretion --> pituitary dwarfism Hypersecretion --> gigantism and acromegaly |
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Secreted by the anterior pituitary lobe Stimulates breast development and promotes and maintains lactation by the mammary glands after childbirth |
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Does not synthesize the hormones it releases, but acts as a storage area for oxytocin and antidiuretic hormone, which are transported to it via neural axons |
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Produced in the hypothalamus and stored in the posterior pituitary lobe Stimulates powerful uterine contractions during birth and milk ejection in the lactating mother |
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Produced by the hypothalamus and stored by the posterior pituitary lobe Causes distal and collecting tubules of the kidneys to reabsorb more water from the urinary filtrate, reducing urine output and conserving water Hyposecretion --> diabetes insipidus Hypersecretion --> edema, headache, disorientation |
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Located in the roof of the third ventricle of the brain Produces melatonin Plays a role in the biological rhythms of the body |
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Secreted by the pineal gland Exhibits a diurnal cycle - peaks at night, making us drowsy, and is lowest around noon Appears to exert some inhibitory effect on the reproductive system that prevents precocious sexual maturation |
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composed of two lobes joined by a central mass, located in the throat, just below the larynx Secretes thyroid hormone and calcitonin |
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Secreted by the thyroid gland Composed of thyroxine and triodothyronine Control the rate of body metabolism and cellular oxidation Hyposecretion --> myxedema (mental and physical sluggishness) Hypersecretion --> elevated metabolic rate, nervousness, etc |
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Secreted by the thyroid gland Decreases blood calcium levels by stimulating calcium salt deposit in the bones (acts antagonistically to parathyroid hormone) |
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Found embedded in the posterior surface of the thyroid gland Secretes parathyroid hormone |
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Secreted by the parathyroid gland The most important regulator of calcium balance of the blood When blood calcium levels decrease, PTH causes release of calcium from bone matrix and causes the kidney to reabsorb more calcium from the filtrate, and stimulates kidneys to convert vitamin D to calcitriol Hyposecretion --> tetany Hypersecretion --> bone fractures |
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Bilobed gland in the superior thorax, between the sternum and the heart Secretes thymlin, thymosins, thymopoeitins |
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Secreted by the parathyroid gland The most important regulator of calcium balance of the blood When blood calcium levels decrease, PTH causes release of calcium from bone matrix and causes the kidney to reabsorb more calcium from the filtrate, and stimulates kidneys to convert vitamin D to calcitriol Hyposecretion --> tetany Hypersecretion --> bone fractures |
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Adrenal medulla and cortex Located atop the kidneys |
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Directly controlled by the sympathetic nervous system Secrete epinephrine and norepinephrine |
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Secretes the corticosteroids (mineralocorticoids like aldosterone, glucocoricoids like cortisol, and gonadocorticoids like androgens and estrogens) |
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Secreted by the adrenal cortex Aldosterone regulates water and electrolyte balance in the extracellular fluids |
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Secreted by the adrenal cortex Cortisol, cortisone, and corticosterone enable the body to resist long-term stressors by increasing blood glucose levels |
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Produced by the adrenal cortex Androgens and estrogens produced throughout life in insignificant amounts Hypersecretion --> abnormal hairiness (hirsutism) and musculinization |
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Located partially behind the stomach in the abdomen Functions as an endocrine and exocrine gland Produces digestive enzymes and blood sugar regulation hormones (insulin and glucagon) |
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Secreted by the pancreas Decreases blood sugar levels Hyposecretion --> diabetes mellitus Hypersecretion --> hypoglycemia |
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Secreted by the pancreas Acts antagonistically to insulin Stimulates the liver to break down glycogen stores to glucose and release it into the blood |
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Female gonads = ovaries, produce estrogens and progesterone Male gonads = testes, produce testosterone |
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Secreted by the ovaries Responsible for the development of the secondary sex characteristics of the female at puberty |
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Secreted by the testes Promotes the maturation of the reproductive system accessory structures, brings about the development of the male secondary sex characteristics, and is responsible for sex drive |
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Pituitary, thyroid, parathyroid, adrenal, pineal, thymus, (pancreas and gonads produce hormones and exocrine products) |
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Primary sex organs (gonads) |
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Testes in males, ovaries in females Produce sex cells called gametes, secrete sex hormones |
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Accessory reproductive organs |
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Ducts, glands, external genitalia |
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