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What are the functions of blood? |
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Definition
Transport, regulation, protection |
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What are the most abundant cells of blood? |
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Definition
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What types of white blood cells are there? |
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Monocytes, lymphocytes, eosinophil, neutrophil, basophil |
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Neutrophils, eosinophils, and basophils are called granular leucocytes because all have cytoplasmic granules that are visible through a light microscope when stained. |
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Lymphocytes and monocytes are called agranular leukocytes because the cytoplasmic granules are not visible under a light microscope because of their small size and poor staining qualities. |
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Definition
Liquid portion of blood; serum remains after plasma clots. |
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3 major categories of plasma are: |
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Definition
Albumins: most abundant & important, produced by liver, contributes to viscosity. Globulins: Antibodies, provide immune system functions, produced by plasma cells. Fibrinogen: help form blood clots, produced by liver |
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Definition
RBCs; major function is gas transport; do not have organelles |
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produces carbonic acid from CO(2) and H(2)0 ( CO(2) makes blood more acidic); important role in gas transport and pH balance |
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binds oxygen to ferrous ion Fe(2+) |
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Definition
composed of four polypeptide chains, two alpha and two beta |
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Definition
percentage of total blood volume occupied by RBCs |
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Hemoglobin concentration of whole blood |
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Definition
men 13-18 g/dL; women 12-16 g/dL |
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Definition
Hemopoiesis: adults produce 400 bill platelets, 200 bill RBCs, and 10 bill WBCs everyday. Hemopoietic tissue produce blood cells; yolk sac produces stem cells |
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Definition
Production of RBCs; negative feedback regulation; main stimulus is hypoxia |
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Nutritional needs for Erythropoiesis |
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Definition
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Definition
Starts in the red bone marrow with a proerythroblast, which divides several times producing a colony-forming unit, then a erythroblast, which ejects its nucleus and becomes a reticulocyte which develops into a mature red blood cell (erythrocyte) within 1 to 2 days. |
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inadequate erythropoiesis or hemoglobin; pernicious anemia: inadequate vitamin B12; iron deficiency anemia, kidney failure and insufficient erythropoietin, aplastic anemia, hemorrhagic anemias, hemolytic anemias |
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Definition
Unique molecules on cell surface. Foreign antigens generate immune response |
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Secreted by plasma cells as part of immune respose to foreign matter. |
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Clumping of the RBCs. Antigen-antibody response in which RBCs become cross-linked to one another |
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Definition
determined by presence or absence of antigens A and/or B on RBC surface |
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Definition
A antigens, anti-B antibody |
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Definition
B antigens, anti-A antibody |
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Both A and B antigents, no antibodies. Universal recipient |
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Neither A nor B antigens, Both anti-A and anti-B antibodies, Universal donor. |
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Opposing Rh blood in woman and fetus, 1st pregnancy ok, however during 1st pregnancy the woman will develop antibodies which will cross the placenta during the 2nd pregnancy and could cause hemolytic disease of newborn. RhoGAM vaccine which binds to the fetal agglutinogens could prevent this disease. |
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High count could mean bacterial infection; release antimicrobial chemicals |
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High count could indicate parasitic infections or allergies; releases enzymes to destroy paracytes |
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Definition
high count could indicate chicken pox, sinusitis, diabetes; secrete histamine (vasodilator); secrete heparin (anticoagulant) |
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Hich count could indicate viral infections; destroy cells (cancer, foreign, and virally infected cells); present antigens to activate other immune cells |
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high count could indicate viral infections |
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Small fragments of megakaryocyte cytoplasm |
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