Term
Three parts of cardiovascular system |
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Definition
Blood, heart, blood vessels |
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# of miles of blood vessels |
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# of miles of blood vessels |
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between vertebral column and sternum, compressions can force blood out of heart into circulationbetween lungs in mediastinum, 2/3 of mass to left of midline |
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encloses heart, inner: serous, outer: fibrous |
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parietal and visceral layer |
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between parietal and visceral layers of serous pericardium, potential space fill with pericardial fluid, reduces friction between two membranes |
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inflammation of pericardium |
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Definition
bleeding into pericardial cavity that compresses heart, potentially lethal |
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epicardium, myocardium, endocardium |
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consists of mesothelium and connective tissue |
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myocardities and endocarditis |
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Definition
inflammation of myocardium and endocardium |
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two upper atria two lower ventricles |
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Definition
auricles small pouches on anterior surface of each atrium that increases capacity sulci - grooves that contain blood vessels and fat and separate the chambers |
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Definition
receives blood for superior and inferior vena cava and the coronary sinum |
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in septum separating the right and left atria, oval depression, remnant of foramen ovale |
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Definition
blood passes from right atrium into right ventricle |
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Definition
forms most of the anterior surface of the heart |
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Term
pulmonary semilunar valve |
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Definition
blood passes from right ventricle to pulmonary trunk through this valva |
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Definition
receives blood from pulmonary veins |
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Definition
blood passes from left atrium to left ventricle through this valve |
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Definition
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blood passes from left ventricle through the this valve into the aorta |
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during fetal life, this shunts blood from pulmonary trunk into aorta. At birth it closes and becomes ligamentum arteriosum. |
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thin because they deliver blood to ventricles |
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ventrical myocardial walls |
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Definition
thicker pump blood greater distances |
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Definition
thinner than left, pump blood into lungs, close by and little resistance |
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Definition
thicker than right, pump blood through body, resistance is greater |
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Term
fibrous skeleton of heart |
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Definition
forms foundation where heart valves attach, points of insertion for cardiac muscle bundles, prevents overstretching of valves, electrical insulator that prevents direct spread of action potentials from atria to ventricles |
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Definition
open and close in response to pressure changes as heart contracts and relaxes |
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Term
atrioventricular (AV) valves |
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Definition
prevent blood flow from ventricles back into atria |
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Term
atrioventricular (AV) valves |
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Definition
prevent blood flow from ventricles back into atria |
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Definition
contract and tighten chordae tendiae which prevents valve cusps from everting and causing back flow |
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allow ejection of blood from heart into arteries but prevent back flow of blood into ventricles |
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Definition
when pressure in the ventricles exceeds pressure in the arteries |
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Definition
left side of heart, it pumps oxygenated blood from the lungs out into vessels of the body |
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Definition
right side of heart is the pump, receives deoxygenated blood from body and sends it to lungs for oxygenation |
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Term
coronary (cardiac) circulation |
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Definition
flow of blood through many vessels that pierce myocardium of heart |
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Term
right and left coronary arteries |
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Definition
principal arteries, branch from ascending aorta and carry oxygenated blood |
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Definition
deoxygenated blood returns to the right atrium via this principal vein |
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damage when blood flow is restored after heart attack, due to free radicals |
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weakened heart cells due to low levels of oxygen carried to myocardium, if permanent called MI, heart attack |
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Definition
shorter in length and larger in diameter than skeletal, squarish in transverse section, exhibit branching |
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cardiac muscles compared to skeletal |
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Definition
same arrangement of actin and myosin, same bands, zones, Z discs, less sarcolasmic reticulum and require Ca +2 for contraction from extracellular fluid |
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Term
atrial and ventricular networks |
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Definition
fibers within networks connected by intercalcated discs, desmosomes and gap junctions, discs allow fibers to work together to each network is functional unit. |
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Term
autorhythmic cardiac muscle cells |
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Definition
self excitable, generate spontaneous action potentials that trigger heart contractions, form conduction system, route to propagate action potential through heart muscle |
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cardiac autorhythmic muscle cells, set rhythm for heart |
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Definition
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Term
components of the conduction system, autorhythmic cells |
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Definition
sinoartrial (SA) node, atrioventricular (AV)node, atrioventricular bundle (bundle of HIS) right and left bundle branches, conduction myofibers (purkinje fibers) |
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Definition
from signals from autonomic nervous system hormones (epinephrineP can change rate and strength but do not establish fundamental rhythm. |
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Term
impulse in ventricular contractile fiber |
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Definition
characterized by rapid depolarization, plateau and repolarization |
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Term
refractory period in cardiac muscle fiber |
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Definition
longer than contraction itself, the time interval when a second contraction cannot be triggered |
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Term
ATP production in cardiac muscle |
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Definition
relies on aerobic cellular respiration for ATO production it also produces some from creatine phosphate |
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Definition
presence in blood indicates injury of cardiac muscle usually MI |
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impulse conduction through heart generates electrical currents, ekg records electrical changes during each cardiac cycle/heartbeat helps determine if conduction pathway is abnormal , if heart is enlarges, if certain regions are damaged |
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Definition
P - wave QRS complex T wave |
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Definition
atrial depolarization, spread of impulse from SA node over atria |
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ventricular depolarization, spread of impulses through ventricals |
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ventricular repolarization |
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represents conduction time from beginning of atrial excitation to beginning of ventricular excitation |
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represents time when ventricular contractile fibers are fully depolarized during plateau phase of the impulse |
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systole/contraction diastole/relaxation of both atria rapidly followed by systole and diastole of both ventricles |
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pressure and volume changes during cardiac cycle |
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Definition
during cycle atria and ventricles alternately contract and relax forcing blood from areas of high pressure to areas of lower pressure |
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Definition
listening to sounds within the body |
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Definition
comes from turbulence in blood flow caused by closure of valves |
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lubb, blood turbulence associated with closing of the atriventricular valves after ventricular systole begins |
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dupp closing of the semilunar vaves close to end of ventricular systole |
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abnormal sound of flow noise heard before, between, or after lubb-dupp or masks normal sounds some caused by turbulent blood flow around valves due to abnormal anatomy or increased volume of flow. |
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Definition
volume of blood ejected from the left or right ventricle into aorta or pulmonary trunk each minute |
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cardiac output calculation |
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Definition
stroke volume (volume of blood ejected by ventricle with each contraction) multiplied by heart rate (number of beats per minute) |
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Definition
ratio between the maximum cardiac output a person can achieve and the cardiac output at rest |
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regulates stroke volume, the degree of stretch in the heart before it contracts |
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forcefulness of contraction of individual ventricular muscle fibers |
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pressure that must be exceeded if ejection of blood from ventricles is to occur |
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Term
Frank-Starlimng law of the heart |
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Definition
a greater preload (stretch) on cardiac fibers just before they contract increases their force of contraction during systole. The Frank-Starling law of the heart equalizes the output of the right and left ventricles and keeps the same volume of blood flowing to the systemic and pulmonary circulations |
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Definition
strength of contraction at any given preload is affected by positive and negative inotropic agents, |
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Term
positive/negative inotropic agents |
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Definition
increase and decrease contractility |
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Term
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Definition
stroke volume increases when positive inotropic agents are present and decreases when negative inotropic agents are present |
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the pressure that must be overcome before a semilunar valve can be open |
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Term
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Definition
blood begins to remain in the ventricles increasing the preload and ultimately causing overstretching of heart and less forceful contractions |
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Term
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Definition
changing heart rate is body's principal mechanism of short term control over cardiac output and blood pressure |
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Term
factors of regulation of heart beat |
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Definition
Autonomic Chemical age, gender, physical fitness, temperature |
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Term
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Definition
Nervous control medulla oblongata's cardiovascular center Proprioceptors, baroreceptors, chemoreceptors monitor factors that influence heart rate Sympathetic impulses increase heart rate and force of contractyion Parasympathetic impulses decrease heart rate |
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Term
factors of regulation of heart beat |
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Definition
Autonomic/ cardiovascular center in medulla oblongata Chemical: hormones, epinephrine, norepinephrine, thyroid Ions: Na+, Ca+2, K+ age, gender, physical fitness, temperature |
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Term
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Definition
develops from mesoderm before the end of the third week of gestation Endothelial tubes develop into 4 chambered heart and great vessels of heart |
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Term
Coronary artery disease (CAD) |
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Definition
heart muscle receives an inadequate amount of blood due to obstruction of blood suppy. Leading cause of death in US, principal causes of obstruction: atherosclerosis, coronary artery spasm, clot in coronary artery. |
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Term
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Definition
process in which smooth muscle cells proliferate and fatty substances, cholesterol and triglycerides (neutral fats) accumulate in wasll of medium and large arteries in response to certain stimuli such as endothelial damage |
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