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A/P I: Chapter 4: Connective Tissues
Histology
55
Anatomy
Undergraduate 2
09/18/2009

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Term
Connective Tissue
Definition

Abundant, found in every organ

Cells separated by extracellular matrix

Many diverse types

Variety of important functions

Term
Types of cells contained in connective tissue
Definition

Blasts

Cytes

Clasts

Term
Blast cells
Definition
Build the extracellular matrix in connective tissue.
Term
Cytes
Definition
Maintain the extracellular matrix in connective tissue.
Term
Clasts
Definition
Breakdown the extracellular matrix in connective tissue.
Term
Categories of Connective Tissue
Definition

Matrix of primarily protein fibers

 

Matrix of protein fibers and ground materials

 

Fluid matrix

Term
Protein fibers of the extracellular matrix in connective tissue
Definition

Collagen fibers

Reticular fibers

Elastic fibers

Term
Collagen fibers
Definition
Collagen strands that appear similar to a coiled rope of 3 polypeptide chains.
Term
Reticular Fibers
Definition
Very fine, short, branching collagen fibers. Not as strong as most collagen fibers, but networks of these fibers fill space between tissues and organs.
Term
Elastic fibers
Definition
Formed by elastin and form a large, interwoven meshwork of spring-like molecules that extend through entire tissue.
Term
Ground Substances of Connective Tissue
Definition

Hyaluronic Acid

Proteoglycan

Adhesive Molecules

Term
Hyaluronic Acid
Definition
Polysaccharide that acts as a lubricant when rubbed and is sticky when touched.
Term
Proteoglycan
Definition
Protein and polysaccharide that traps water.
Term
Adhesive molecules
Definition

Hold Proteoglycan aggregates together. Are named with the suffix -nectin.

 

Term
Three types of adhesive molecules
Definition

Chondronectin

Osteonectin

Fibronectin

Term
Chondronectin
Definition
Found in the ground substance of cartilage.
Term
Osteonectin
Definition
Found in the ground substance of bone.
Term
Fibronectin
Definition
Found in the ground substance of fibrous connective tissue.
Term
Two major categories of Connective Tissue
Definition

Embryonic

Adult

Term
Six types of Adult Connective Tissue
Definition
  1. Loose
  2. Dense
  3. Special
  4. Cartilage
  5. Bone
  6. Blood
Term
True Connective Tissue
Definition
Loose and Dense Connective tissues
Term
Loose Connective Tissue
Definition
Areolar tissue: protein fibers that form a network with an open weave.
Term
Dense Connective Tissue
Definition
Protein fibers form thick bundles
Term
Two types of Dense Connective Tissue
Definition

Dense Regular Collagenous

Dense Regular Elastic

Term
Dense Regular Collagenous C.T.
Definition
Abundant collagen fibers that resist stretching.
Term
Examples of Dense Regular Collagenous C.T.
Definition

Tendons: connecting muscle to bone

 

Ligaments: connecting bone to bone

Term
Dense Regular Elastic C.T.
Definition
Parallel bundles of collagen fibers with abundant elastic fibers.
Term
Example of Dense Regular Elastic C.T.
Definition
Nuchal ligaments: found in vocal chords.
Term
Dense Irregular Collagenous C.T.
Definition
Protein fibers arranged randomly. Forms innermost layer of the dermis of the skin, scars, capsules of kidney and spleen.
Term
Dense Irregular Elastic Connective Tissue
Definition
Strong yet elastic. Bundles and sheets of collagenous and elastic fibers oriented in multiple directions. Found in walls of elastic arteries.
Term
Adipose Tissue
Definition

Site of fat storage.

Very little extracellular matrix.

Two types: yellow and brown.

Major vacuole filled with fat.

Term
Yellow Adipose Tissue
Definition
Most abundant adipose tissue.
Term
Brown Adipose Tissue
Definition
Specialized adipose tissue for heat generation, helps maintain body temperature.
Term
Reticular Connective Tissue
Definition
Composed of reticular fibers and cells remain in close contact. Specialized framework for lymphatic tissue, bone marrow and the liver.
Term
Hematopoietic Connective Tissue
Definition
Red bone marrow.
Term
Hematopoietic Connective Tissue
Definition
Forms blood cells, located within bone marrow, found in ends of long bones and inside smaller bones.
Term
Cartilage
Definition
Rigid matrix of protein fibers and proteoglycan.
Term
Three Subtypes of Cartilage
Definition

Hyaline

Fibrocartilage

Elastic Cartilage

Term
Hyaline Cartilage
Definition
Very smooth matrix with evenly dispersed collagen. Found in covering over long bones, growth plates and the embryonic skeleton.
Term
Epipheseal disk
Definition
Growth plate
Term
Fibrocartilage
Definition
Collagen arranged in thick bundles. Provide protective cushioning in areas that take a lot of abuse, like vertebrae, knees and the jaw.
Term
Elastic Cartilage
Definition
Contains elastic fibers dispersed throughout the matrix and found in areas that have rigid but elastic properties, such as the ears.
Term
Bone
Definition
Contain osteocytes located within lacunae and the matrix is primarily mineral, calcium and hydroxyapatite. Protein fibers are primarily collagen.
Term
Two subtypes of Bone
Definition

Compact Bone

Cancellous Bone

Term
Cancellous Bone
Definition
Contains large open spaces filled with hematopoietic tissue. Lightweight and rapid remodelling, also known as trebecular or spongy.
Term
Compact Bone
Definition
Contains central canal surrounded by lamella. Forms the strong outer shell of most bones for strength and support. Slow remodelling rate. Also known as cortical or osteonic.
Term
Blood
Definition
Connective tissue that has cells suspended in a fluid matrix and is mobile.
Term
Three types of Blood
Definition

Red Blood Cells

White Blood Cells

Platelets

Term
Erythrocytes
Definition
Red Blood Cells
Term
White Blood Cells
Definition
Leukocytes
Term
Platelets
Definition
Thrombocytes
Term
Hemoglobin
Definition
Red blood cells contain this protein, which functions to transport oxygen.
Term
Function of White Blood Cells
Definition
Fight infection. Move by amoeboid movement of diapedisis.
Term
Function of Thrombocytes
Definition
Clotting
Term
Colloidal Solution
Definition
A fluid with suspended substances that don't settle out.
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