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A&P Exam 3
n/a
111
Anatomy
Undergraduate 1
03/30/2009

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Term
Albumin
Definition
osmotic pressure
Term
Alpha and Beta Globulins
Definition
transport and clotting
Term
Gamma Globulins
Definition
defenses
Term
Fibrinogen
Definition
clotting
Term
Amino Acids in hemoglobin
Definition
holds heme group which hold irons which interacts with oxygen for pigment
Term
Transport of CO2
Definition
`10% dissolved, 30% on hemoglobin, 60% on carbonic acid
Term
Reticuloctye
Definition
loses nucleus before bone marrow
Term
Erythrocyte
Definition
mature/dead cell
Term
Erythropoietin control of erythopoiesis
Definition
monitors oxygen delivery in kidneys. effector site is bone marrow and makes more RBC
Term
Heme excretion
Definition
spleen (red) -> liver (green-bile) -> GI tract (brown)
Term
Neutrophils
Definition
40-70%. picks up neither basic or acidic. dangerous enzymes, first to arrive. Phagocyte
Term
Eosinophils
Definition
picks up acidic dye. allergic response. 1-7%. worm infestation.
Term
Basophils
Definition
0-1%. basic blue dye. histamine (inflammation) and heparine (prevents clotting)
Term
Monocytes
Definition
largest, come later, kill better. 4-8%. Phagocyte or isolate.
Term
Thrombocytes
Definition
Platelets- portion of cells from marrow for clotting
Term
Intrinsic Pathway
Definition
Hageman Factor
Term
Extrinsic Pathway
Definition
Tissue thromboplastin
Term
Common Pathway to Clotting
Definition
Calicum, platelet phospholipid, prothrombin, thrombin, fibrinogen, fibrin, clot
Term
Breakdown of clot
Definition
plasminogen (inactive), plasmin (active, breaks down clot)
Term
Septum
Definition
connective tissue between two sides of heart
Term
Flow
Definition
= pressure1-pressue2/resistance
Term
Resistance
Definition
= number of molecule/size of box
Term
SA node
Definition
highest leak of Na+ comes to threshold 100 times/min. paces rest of system
Term
Atrial Gap Junctions
Definition
between right and left atrium
Term
Atrioventricular (AV) node
Definition
can comes to threshold without SA node
Term
Bundle of His
Definition
if it dies, put in pacemaker. electrical conduction goes through here.
Term
Purkinje fibers
Definition
keep synchrony
Term
P wave
Definition
depolarization of atrium
Term
QRS wave
Definition
depolarization of ventricle
Term
T wave
Definition
depolarization of ventricles
Term
Ventricular Filling
Definition
late diastole; from T to P for next QRS
Term
Isovolumetric ventricular contraction
Definition
early systole; ventricle begins to contract but not pumping out any blood. volume stays the same. first heart sound.
Term
Ventricular ejection
Definition
late systole; pump out of ventricle before atrium contracts
Term
Isovolumetric relaxation
Definition
early diastole; no blood flow. 2nd heart sound
Term
First heart sound
Definition
closing of AV valve
Term
Second heart sound
Definition
closing of aortic valve
Term
End diastolic volume
Definition
at QRS (130-140)
Term
End systolic volume
Definition
T wave (70-65)
Term
Stroke Volume (SV)
Definition
amount pumped out (65-75)
Term
Ejection Fraction
Definition
Stroke volume/end diastolic volume
Term
Cardiac Output
Definition
heart rate X stroke volume
Term
Pressure in R. and L. ventricle
Definition
20 and 120
Term
Pressure
Definition
HR X SV X Resistance
Term
Blood Transfusion
Definition
must have Nitrous Oxide to keep hemoglobin carrying oxygen
Term
Controls of Cardiac Output (3 physical, 2 neuroendocrine)
Definition
respiratory pump, skeletal muscle pump, venous constriction, sympathetic and parasympathetic
Term
Wall order of arteries
Definition
lumen, tunica intima (epithelial tissue), tunica media (smooth muscle), tunica adventitia (conn. tissue, tough)
Term
Capillary Walls
Definition
lumen and intima
Term
Types of Capillaries
Definition
Continuous (1-blood brain), Fenestrated (2-GI tract, kidneys), Sinusoids (multiple- liver)
Term
Hepatic Portal Circulation
Definition
nutrients and oxygen to liver. direct delivery. 1st cap in GI tract -> liver ->portal vein -> 2nd cap in liver -> hepatic vein -> inferior vena cava
Term
Hypophyseal Portal Circulation
Definition
1st cap -> hypo portal vein -> 2nd cap -> pituitary vein -> superior vena cava. delivers releasing hormones
Term
Systolic Pressure
Definition
pumping into arteries, highest
Term
Diastolic Pressure
Definition
pumping out of arteries, lowest
Term
Pulse Pressure
Definition
systole- diastole
Term
MAP estimate in resting condition
Definition
DP + 1/3PP = MAP ~93 mmHG
Term
MAP estimate with stress
Definition
DP + 1/2 PP = MAP. ~ 100mmHG
Term
Resistance
Definition
length of tube X fluid viscosity/ radius of tube^4
Term
MAP=
Definition
HR X SV X TPR
Term
Blood Flow through Organs (BFo)
Definition
MAP/Ro
Term
Control of MAP: Baroreceptors
Definition
Carotid and Aortic Baroreceptors, hypothalamus & medulla, Increase sympathetic, Heart muscle( HR&SV), Arterioles (Contrict-TPR, Veins (Contrict- VR EDV SV), Increase MAP
Term
Control of MAP: Renal
Definition
Kidney Barorecptors, Kidneys, Increase Renin- Angiotensin and Aldosterone, Arterioles (Constrict- TPR), Kidneys (NA+ and H2O retention, VR EDV SV), Increase MAP
Term
Control of MAP: Hypothalamic
Definition
Hypothalamic Baroreceptors, Hypothalamus, Increase ADH (vasopressin), Arterioles (constrict- TPR), Kidneys (H2O retention- VR, RDV, SV), Increase MAP
Term
Control of MAP: Capillary
Definition
Effects Capillaries, Water shifts into them, Increase VR EDV SR, Increase MAP
Term
Renin Angiotensin Aldosterone
Definition
Liver releases angiotensinogen, Decrease MAP, Kidneys release renin, activates angiotensin, Increase TPR and Adrenals release aldosterone, Kidneys salt water retention, Increase SV
Term
Increases of blood flow in exercise
Definition
heart, skeletal muscle, skin
Term
Net Movement =
Definition
Filtration - absorption. positive is out, negative is in
Term
Filtration
Definition
out, hydrostatic pressure in capillaries (35) - hydrostatic pressure in intersititum (usually 0)
Term
Absorption
Definition
in, colloid osmotic pressure in capillaries (28) - colloid osmotic pressure in intersisitium (3)
Term
Lymph
Definition
formation by net filtration from blood. returned to venous circulation. Water, crystalloids, proteins, fats, WBC. (NO RBC)
Term
Functions of respiratory system
Definition
exchange of gases, regulation of pH, defenses, emotion and expression
Term
Alveoli
Definition
gas exchange. Type 1: squamous epithelia, Type 2: surfactant producing, alveolar macrophages (WBC, defenses)
Term
Inspiratory muscles
Definition
diaphragm for resting, external intercostals aid deep breaths
Term
Expiratory muscles
Definition
passive when resting, internal intercostals and ab muscles
Term
Bulk Flow for Breathing
Definition
pressure in alv - pressure in atm/ resistance
Term
Pressure in alveolar during inspiration and expiration
Definition
less than 0 air in, end of inspiration no air flow- lungs = pressure in atm, elastic recoil pressure greater than 0, pressure same as atm at end of expiration- no air flow
Term
Contraction Control in Bronchiole Smooth Muscle
Definition
Neuro -> ANS -> Para. -> Cholinergic receptors -> contraction -> constriction. Local -> decrease CO2 -> Contraction -> constriction
Term
Dilation Control in Brochiole Smooth Muscle
Definition
Neuro -> ANS -> epi -> Beta 2 receptors -> Relaxation -> Dilation. Local -> Increase CO2 -> Relaxation -> Dilation
Term
Surfactant
Definition
overcomes surface tension to increase compliance and decrease work of breathing. Type 2 cells produce phospholipid, sits in between water molecules
Term
Resting tidal volume
Definition
500 ml.
Term
Inspiratory reserve volume
Definition
3000 ml. additional air that can be inhaled.
Term
Expiratory reserve volume
Definition
1 liter. additional air you can exhale after normal exhalation.
Term
Residual Volume
Definition
1 liter. amount of air left in lungs after maximal exhalation.
Term
Inspiratory Capacity
Definition
4 liters.
Term
Functional Residual Capacity
Definition
2 liters. residual + expiratory residual
Term
Vital Capacity
Definition
5 liters. everything minus out.
Term
Total Lung Capacity
Definition
6 liters.
Term
Minute Respiratory Volume
Definition
12 X 500 ml, RR X TV
Term
Anatomical Dead Space
Definition
space with no gas exchange. 150 ml.
Term
Calculation of alveolar ventilation
Definition
RR X (TV - ADS)
Term
Reflex Control of Ventilation
Definition
increase in CO2 and H in CSF and carotid &aortic bodies -> vagus and glossopharyngeal nerves -> medullary respiratory neurons, forced expiration, autorhythmic (pons) -> phrenic and intercostal nerves -> diaphragm and intercostal muscles -> increase ventilation
Term
Brain Stem Control of Ventilation (Pons)
Definition
direct for H=, pneumotaxic center, inhibits inspiratory, shorten inspiration, smooths ventilation
Term
Voluntary Control of Ventilation
Definition
speech, swallowing, coughing, crying, ect., cerebral cortex, varies with activity
Term
Time for RBS equilibrium to occur
Definition
.75 sec
Term
Bronchial Smooth Muscle Prediction
Definition
increased Co2 = dilation. decreased CO2 = constriction
Term
Pulmonary arterial Smooth Muscle
Definition
MATCH BLOOD FLOW TO AIR FLOW. Increased CO2 = constriction, decreased CO2 = dilation
Term
Systemic arterial Smooth Muscle
Definition
Deliver blood flow to areas of high metabolic use. Increased CO2 = dilation. Decreased CO2 = constriction
Term
Partial Pressure of Oxygen
Definition
PP= atm pressure X % of gas. can change where you are at (lower is more pressure) or amount of oxygen (usually 20%)
Term
Lower pulmonary HPc
Definition
decreases MAP and filtration and net absorption. prevents pulmonary edema which slows diffusion.
Term
Binding of Oxygen to Hemoglobin
Definition
Hb+O2 -> Hb02. (replaces in lungs) HbO2 -> Hb +02 (uses in tissue)
Term
Law of Mass Action
Definition
determines direction of reaction
Term
Partial Pressure of O3 on Hb Saturation Curve
Definition
100 mm/hg in lungs, completely saturated. 20 mm/hg in tissue. about 25% delivered, 75% reserved on hb.
Term
Transport of CO2
Definition
CO2 + H2O -> H2CO3 (carbonic anhydrase in tissue) revered in lungs. H+ + HCO3 in tissue, reversed in lungs.
Term
Functions of Urinary System
Definition
control of fluid, electrolyte and acid base balance, excretion of wastes, endocrine (erythropoietin, renin, vit d)
Term
Internal of Kidney
Definition
renal cortex (outer), renal medulla (into tubes), major and minor calyces (collecting areas), renal pelvis (drains into picket then to ureter)
Term
Creating Urine
Definition
renal cortex and medulla
Term
Vascular Component of urine formation
Definition
afferent arterioles (into capillaries), glomerulus (filtered), efferent arteriole (going out), peritubular capillaries (wrapping around tubule)
Term
Tubule Component of urine creation
Definition
Om cortex of medulla. Glomerular capsule (filters into), proximal convoluted tubule (twisting), loop of henle (countercurrent), distal convoluted tubule, collecting duct (collect nephrons)
Term
Juxtaglomerular Apparatus
Definition
secretes renin, nothing to do with urine
Term
Calculation of Glomular Filtration Rate (GFR)
Definition
amount filtered = amount excreted. Volume(u) X (C)u/ (C)p
Term
Reabsorpiton
Definition
Active transport (Na and Ca), Cotransport (K, gl, aa, ua), Osmosis (H2O), Facilitated Diffusion (Cl, SO4, PO4), Simple Diffusion (urea)
Term
Loop of Henle
Definition
reabsorbs Na+ and secretes K and H. one cation for one cation.
Term
Simple Diffusion secretion in urine
Definition
NH3 (ammonia)
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