Term
What are three functions of blood? |
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Definition
Transportation, Regulation, Protection |
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Term
What does the blood regulate? |
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Definition
Temperature, Ph, electrolyte balance, Maintain fluid balance |
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Term
What connective tissue helps from loosing blood AND helps prevent infection? |
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Definition
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Term
Blood comprises what percentage of body weight? |
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Definition
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The average person has how much blood? |
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Definition
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Definition
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Blood is slightly acidic or basic? |
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Definition
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Term
Why do males have slightly higher blood production? |
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Definition
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Term
What are the physical qualities of blood? |
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Definition
Opaque, salty, metalic taste, Viscus |
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Term
What are the percentages of plasma vs formed elements in blood? |
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Definition
55% plasma, 45% formed elements |
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Term
What is the difference between plasma and serum? |
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Definition
Serum has no clotting protiens or platelets |
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Term
A test for formed elements is called? |
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Definition
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Term
What is the percentage of plasma proteins in blood? |
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Definition
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Term
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Definition
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Term
What blood protein transports lipids, steroids and hormones? |
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Definition
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Term
Gamma Globulins are made by? |
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Definition
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Term
How are small ions kept in the bloodstream? |
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Definition
They are bound to Gamma Globulins |
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Term
Fibrinogens are _____________ proteins. |
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Definition
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Term
Fibrinogen has to do with what process? |
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Definition
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Term
All formed elements in blood come from? |
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Definition
Hemocytoblasts (stem cells) |
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Term
Most hemocytoblasts become? |
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Definition
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Term
What type of cell does NOT come from myeloid stem cells? |
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Definition
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Term
Platelet formation is called? |
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Definition
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Term
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Definition
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Term
What type of cell comprises 33% of all cells in the body? |
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Definition
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Term
About how many RBCs are in 1 cubic mm? |
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Definition
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Term
How long does a RBC live? |
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Definition
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Term
What are the benefits of the RBC's shape? |
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Definition
provides more surface area, allows it to travel in very small vessels, They can stack like dimes (roulaeu) |
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Term
What does a RBC NOT have that other cells have? |
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Definition
Nucleus, Ribosomes, Mitachondria |
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Term
What comprises 95% of a RBC? |
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Definition
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Term
A hemoglobin is a ___________________ structure and comprised of 4 __________________ structures. |
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Definition
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Term
In the middle of each tertiary group in a hemoglogin is a ? |
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Definition
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Term
How many iron ions can 1 hemoglobin hold? |
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Definition
4 (one in each heme group) |
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Term
About how many hemoglobins are in each RBC? |
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Definition
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Term
About how many oxygen molecules (each molecule is O2) can an RBC hold? |
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Definition
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Term
When Hgb (hemoglobin) carries oxygen it is called? |
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Definition
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Term
When Hgb (hemoglobin) has no oxygen it is called? |
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Definition
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Term
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Definition
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Term
At the end of a RBCs life what percentage are filtered out through the kidney? |
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Definition
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Term
What causes the yellow color of urine? |
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Definition
The broken down hemoglobin |
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Term
What is the meaning of life? |
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Definition
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Term
At the end of the RBCs life what happens to 90% of them? |
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Definition
They get phagosotized by the macrophage cells |
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Term
The Globin part of the RBC is broken down into ______________ at the end of the RBCs life? |
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Definition
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Term
When the iron ion is pulled out of the heme group, it is bound to this protein. |
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Definition
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Term
What is iron stored as in the bone marrow and liver? |
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Definition
Ferritin and hemosiderin. |
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Term
A macrophage turnes the nitrogen from a broken down RBC first into______, then into_____? |
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Definition
Biliverdin, unconjugated bilirubin |
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Term
Where is the unconjugated bilirubin turned into conjugated bilirubin? |
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Definition
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Term
To make RBCs, what basic ingredients are needed? |
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Definition
Amino acids, B12, B6, Iron |
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Term
What are the five phases of hemostatis? |
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Definition
Vascular, Platelet phase, Coagulation, clot retraction, Fibrinolysis. |
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Term
What function is common to all WBCs? |
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Definition
Diapedesis, Positive chemotaxis |
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Term
What three types of WBCs can do phagocytosis? |
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Definition
Neutrophils, Monocytes, Eosinophils |
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Term
What regulates RBC production? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
What are three causes of Anemia? |
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Definition
Decreased RBC Production, Hemoglobin caused, Genetic |
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Term
Decreased RBC production by destruction of bone marrow is what disease? |
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Definition
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Term
If you don't have enough vitiman B12, what type of anemia can you get? |
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Definition
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Term
How many WBCs can be in 1 cubic mm? |
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Definition
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Term
How long does it take for RBCs to get into the bloodstream and mature? |
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Definition
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Term
What is an immature RBC called? |
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Definition
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Term
Basophils comprise what percentage of WBCs? |
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Definition
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Term
AB type blood has no ________________ but has both A and B __________________ |
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Definition
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Term
Name three functions of platelets? |
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Definition
Transport chemicals important to clotting, Can become sticky and form platelet plug, slightly contractile. |
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Term
What is a normal platelet count? |
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Definition
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Term
Lack of clotting factor ____ leads to Hemophelia? |
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Definition
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Term
Where are many clotting factors made? |
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Definition
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Term
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Definition
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Term
What is the end product of the extrinsic pathway (hemostasis)? |
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Definition
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Term
What is the end product of the intrinsic pathway (hemostasis)? |
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Definition
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Term
A vitamin K deficiency leads to a decrease in this notable clotting factor? |
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Definition
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Term
What prevents the AV valves from swinging into the atria? |
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Definition
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Term
A place in the heart that spontaneously depolarizes but is not a node is called? |
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Definition
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Term
Durring ventricular systole, at one point all four valves are closed, this is called? |
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Definition
Isovolumetric Contraction |
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Term
Why is the absolute refractory period of heart muscle so long? |
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Definition
Due to the Calcium in the cell |
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Term
Cardiac output is (define) |
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Definition
Heart Rate X Stroke Volume |
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Term
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Definition
Filling time and Venous Return |
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Term
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Definition
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Term
What are the four layers of the Tunica Intima? |
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Definition
Endothelium, Basement Membrane, Lamina Propria (muscle), Internal elastic membrane |
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Term
What are the Three general structures of a blood vessel wall? |
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Definition
Tunica Intima, Tunica Media, Tunica Externa |
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Term
The right atrium develops how much pressure? |
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Definition
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Term
The right ventricle generates _________ mm Hg. |
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Definition
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Term
The left ventricle develops how much pressure? |
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Definition
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Term
The arterial side begins at the ____________ and ends at the ______________. |
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Definition
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Term
What are the three factors that contribute to total peripheral resistance? |
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Definition
Vascular resistance, Viscosity, Turbulance. |
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Term
What are the five general classes of blood vessels. |
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Definition
Arteries, areterioles, Capillaries, Venules, veins |
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Term
Where would you find fenestrted capillareis? |
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Definition
Endocrine Glands, Choroid Plexus of brain, kidneys |
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Term
What layer of tissue do veins lack? |
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Definition
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Term
The arteriole lacks what parts of the tunica interna? |
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Definition
Smooth muscle layer and internal elastic membrane |
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Term
Capillaries exist as capillary __________. |
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Definition
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Term
What holds a capillary together? |
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Definition
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Term
Do veins or arteries have more stretch in the Tunica Media? |
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Definition
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Term
What is the blood pressure loss in the capillary beds? |
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Definition
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Term
Which vessels have the most effect on blood flow and pressure? |
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Definition
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Term
What can cause turbulence in blood flow? |
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Definition
Cholesterol buildup, thrombus |
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Term
Perfusion is effected by? |
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Definition
Cardiac output, peripheral resistance and Blood pressure |
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Term
Short term regulation of blood pressure is by the? |
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Definition
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Term
Chemoreceptors are located? |
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Definition
Aortic Arch, Carotid Sinus |
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Term
Chemoreceptors monitor ________ concentration in the plasma (pH) |
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Definition
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Term
An increase in CO2 lead to more or less hydrogen ion concentration? |
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Definition
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Term
Complete this formula: Carbon dioxide + water to carbonic acid to _____________ + bicarbonate. |
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Definition
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Term
Chemoreceptors are hooked up to the ? |
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Definition
Medulla Oblongata cardio regulatory and vasomotor centers. |
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Term
Long term blood pressure regulation is done by? |
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Definition
Endocrine system (hormones) |
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Term
When BP is low ADH is released to increase BP, this is made by the? |
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Definition
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Term
Angiotension II is made by a plasma protein called? |
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Definition
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Term
EPO increases ______ production? |
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Definition
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Term
____________ is made by the adrenal gland in response to angiotension II to increase BP. |
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Definition
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Term
When BP is high, _______ is produced by cardiac muscle cells of the _____________ atrium. |
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Definition
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Term
What triggers the production of ANP (Atrial natriuretic peptide)? |
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Definition
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Term
The three states of circulatory shock are? |
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Definition
Compensated, Progressive, Irreversible |
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Term
The second stage of shock occurs at ___% of blood loss? |
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Definition
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Term
Central Ischemic Response occurs at _____ Systolic BP? |
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Definition
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