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What interacts to maintain homeostasis? |
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Chemical, thermal and neural factors |
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Three interdependent components of control mechanisms? |
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Receptor (stimuli, responds to changes), Control Center (determines the set point), Effector (provides the means to respond to stimuli) |
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turns off something, makes it less powerful. Example: Regulation of room temperature |
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the body's second great controlling system influences metabolic activities of cells by means of hormones. |
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Pituitary Gland, Thyroid, parathyroid, adrenal, pineal, and thymus |
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What produces hormones and exocrine products? |
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Definition
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What is the Hypothalamus? |
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a chemical substance produced and secreted in one part of an organism and transported via the ECF (extracellular fluid) to another organ where it has a specific effect. |
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intracellular or on the plasma membrane |
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Hormones produce one or more of what cellular changes? |
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Definition
Alter plasma membrane permeability Stimulate protein synthesis Activate or deactivate enzyme systems Induce secretory activity Stimulate mitosis |
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Target cell activation depends on 3 factors |
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Definition
Blod levels of the hormone Relative number of receptors on the target cell The affinity of those receptors for the hormone |
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Concentrations of circulating hormone reflect: |
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Definition
Rate of release Speed of inactivation and removal from body |
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Hormones are removed from the blood by: |
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Definition
Degrading enzymes The kidneys Liver enzyme systems |
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Blood Levels of Hormones: |
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Definition
Vary only within a narrow desirable range Are typically controlled by negative feedback systems HUMORAL stimuli (blood) NEURAL stimuli (nerves) HORMONAL stimuli (hormones triggering another) |
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Definition
secretion of hormones in direct response to changing blood levels of ions and nutrients |
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Sample of Humoral Stimuli |
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Definition
declining blood Ca2+ concentration stimulates the parathyroid glands to secrete PTH (parathyroid hormone)
PTH causes Ca2+ concentrations to rise and the stimulus is removed |
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nerve fibers stimulate hormone release |
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Example of Neurol Stimuli |
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Preganglionic sympathetic nervous systems (SNS) fibers stimulate the adrenal medulla to secrete catecholarmines |
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release hormones in response to hormones produced by other endocrine organs |
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Example of Hormonal Stimuli |
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The hypothalamic hormones stimulate the anterior pituitary
In turn, pituitary hormones stimulate targets to secrete still more hormones |
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Hypothalamus and Pituitary (Hypophysis) |
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two-lobed organ that secretes nine major hormones |
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posterior lobe (neural tissue) and the infundibulum. Receives, stores, and releases hormones from the hypothalamus Branchy |
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anterior lobe, made up of glandular tissue. Synthesizes and secretes a number of hormones Cellular |
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There is a hypothalamic-pituitary relationship of the anterior lobe as a vascular connection. The hypophyseal portal system, consists of: The primary capillary plexus The hypophyseal portal veins The secondary capillary plexus |
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