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859-2 Women's Health
Implanon, Genital warts, Pap vaccine
29
Nursing
Graduate
12/01/2011

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Cards

Term
Implanon MOA
Definition

supresses LH surge (necessary for ovulations)

thickens mucus (barrier to sperm penetrations)

thinning of the lining of the uterus (prevents implantation)

Term
Risks of Implanon
Definition
Irregular uterine bleding, insertion complications, possible weight gain, ovarian cysts, headaches, loss of libido, vaginal dryness, clinician dependency, increased risk of thromboembolic conditions, relatively new method
Term
Benefits of Implanon
Definition
High efficacy, easy to use, discrete, no adverse effect on acne, relief of dysmenorrhea, relief of endometriosis symptoms, reduced risk of ectopic, no estrogen, reversible, 
Term
What is Implanon?
Definition

Single flexible rod, 4cm long,

made up of ethylene vinyl acetate,

containing 68mg of etonogestrel

(3-keto-desogestrel)

Term
How much hormone is released by Implanon?
Definition

67ug/day for the first 2 years,

then 30ug/day

Term
How soon after placement is Implanon effective?
Definition
Concentrations that inhibit ovulation are reached within 8 hours. A steady state is reached after 4 months
Term
How long is Implanon effective?
Definition

3 years;

can inhibit ovulation for 2.5 years

Term
When should Implanon be inserted?
Definition

Insert day 1-5;

if inserted after day 7, use a back up method

Term
Contraindications of Implanon
Definition

Active thrombophlebitis, or thromboembolic disease, undiagnosed genital bleeding, acute liver disease, benign or malignant liver tumors, known or suspected breast cancer

Heavy smoker, hx ectopic pregnancy, DM, high cholesterol, HTN, heart disease, gallbladde disease, immunocompromised

Term
Where is Implanon inserted?
Definition

Placed subdermally in the upper inner arm;

crease between the biceps and triceps

Term
How effective is Implanon?
Definition

Just as effective as IUDs and sterlization;

failure rate 0.01%

Term
Cost of Implanon
Definition

Insertion $400-$800;

removal $100-300

Term
Best populations
Definition
Can't have estrogen (breastfeeding), want to delay pregnancy 2-3 yrs, difficulty using other forms of contraception, not yet ready fo sterilization, hx of heavy bleeding, have chronic illnesses and health will be threatened by pregnancy
Term

What is the cause of genital warts 

(condyloma acuminta)?

Definition

HPV

90% caused by types 6 and 11

Term
Symptoms of genital warts
Definition
May be asymptomatic or cause anogenital pruitus, burning, dyspareunia 
Term
Physical findings of genital warts
Definition

cauliflower-lilke, flat, papular, keratotic with a thick horny layer, fond-like

 

found in the vulvular, perineal, and perianal areas as well as vaginal walls, the cervix, in the urethra, anus, and mouth

Term
Diagnosis/labs of genital warts
Definition

visual inspection and history

 

biopsy-if diagnosis unclear, getting worse, recurrent, or immunocompromised patient

 

colposcopy-for flat warts that are difficult to see (not recommended by varney)

 

screen for other STIs

Term
Treatment of genital warts
Definition

Time- may resolve on own

 

Patient applied:podofilox gel, imiquimod cream, sinecatechins ointment

Provider-administered: cryotherapy w/ liquid nitrogen or cryoprobe, TCA (trichloric acid), BCA (bichloroacetic acid), podophyllin resin, surgical removal  

Term
Prevention of genital warts
Definition

Gardasil 

protects against 6, 11, 16, 18

Term
Patient education-genital warts
Definition
use condoms, abstain from sex during treatment, annual paps, stop smoking-will reduce risk of HPV neoplasia
Term
Implications for pregnancy-genital warts
Definition

usually incease in size and number (due to decreased immune system), regress after pregnancy, excessive growth may cause a difficult labor, excessive bleeding-may require c-section

 

imiquimod, siecagechins, podophyllin, and podofilox should not be used in pregnancy

Term
What strands of HPV does Gardasil protect against?
Definition

6, 11: 90% of warts

16, 18: 70% of cervical cancers

Term
At what age should the gardisil vaccine be administered
Definition
9-26
Term
Can the gardisil vaccine be adminstered with a history of cervical cancer or genital warts?
Definition
Yes.
Term
How is gardisil adminstered?
Definition

Intramuscularly, 3-series injection at 0, 2, and 6 months

minimum of 4 weeks between 1 and 2, minimum of 12 weeks between 2 and 3, do not restart if interrupted

Term
Do patients need to continue getting regular paps if they have aleady recieved the gardisil vaccine?
Definition
Yes, they may have been infected before administration, and the vaccine does not protect against 30% of cervical cancers
Term
Is gardisil recommended during pregnancy?
Definition
No, it is a pregnancy B category but not recommended
Term
Can gardisil be given to lactating women?
Definition
Yes.
Term
Cervarix vaccine
Definition

Only effective against HPV types 16 and 18

which cause cervical cancer

no protection against genital warts

 

not tested or licensed for use in males

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