Term
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Definition
densely packed rodlick elements make up 80 percent of cell volume exhibit striations: perfectly aligned repeating series of dark a bands and light i bands |
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Term
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Definition
smallest contractile unit of a muscle fiber the region of a myofibril between two successive z disks composed of thick and thin myofilaments composed of contractile proteins |
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features of a sarcomere: thick filaments |
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Definition
run the entire length of an A band |
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Term
functions of a sarcomere: thin filaments |
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Definition
run the length of the i band and partway into the a band |
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Term
features of a sarcomere: z disk |
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Definition
proteins that anchor thin filaments |
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Definition
lighter midregion where filaments do not overlap |
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Definition
protein that hold adjacent thick filaments together |
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Term
ultrastructure of thick filaments |
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Definition
composed of the protein myosin - myosin tails - myosin heads are atpase enzymes |
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Term
ultrastructure of thin filaments |
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Definition
twisted strand of the protein actin bears active sites for myosin head attachment during contraction |
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Term
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Definition
stores ca2 network of SER surrounding each myofibril |
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Term
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Definition
continuous with the sarcolemma penetrates cell's interior at each A band-I band junction - t tubules conduct impulses deep into muscle fiber |
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Term
Events at the Neuromuscular Junction -Axons of motor neurons: |
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Definition
travel from the central nervous system via nerves to skeletal muscles |
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Events at the Neuromuscular Junction - Each axon: |
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Definition
forms several branches as it enters a muscle |
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Term
Events at the Neuromuscular Junction - Each axon ending forms: |
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Definition
a neuromuscular junction with a single muscle fiber |
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Term
Events at the Neuromuscular Junction - Axon terminal and muscle fiber are: |
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Definition
separated by the synaptic cleft |
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Term
Events at the Neuromuscular Junction Synaptic vesicles of axon terminal contain: |
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Definition
the neurotransmitter acetylcholine |
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Term
Events at the Neuromuscular Junction - Junctional folds of the sarcolemma contain: |
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Definition
Ach receptors (motor end plate) |
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Term
Events at the Neuromuscular Junction - A nerve impulse: |
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Definition
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Term
Events at the Neuromuscular Junction - Ach is: |
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Definition
released an it binds with the receptors on the sarcolemma |
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Term
Nerve stimulus and action potential: |
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Definition
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Term
Role of calcium in contraction - low intracellular calcium concentration: |
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Definition
Active sites on actin are blocked Myosin heads cannot attach to actin muscle fiber relaxes |
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Term
Role of calcium in contraction - high intracellular calcium concentration |
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Definition
Calcium causes binding sites on actin to be exposed Events of the cross bridge cycle occur When nervous stimulation ceases calcium is pumped back into the sarcoplasmic reticulum and contraction ends |
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Term
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Definition
Continues as long as the calcium signal and adequate atp are present Cross bridge formation: myosin head attaches to thin filament Working (POWER) stroke myosin head pivots and pulls thin filaments toward the M line Cross bridge detachment - atp attaches to myosin head and the cross bridge detaches "cocking of the myosin head": energy from hydrolysis of atp cocks the myosin head into the high energy state |
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