Shared Flashcard Set

Details

6 HIV/AIDs
Stages, Epidemiology, Treatment
9
Medical
Post-Graduate
03/17/2009

Additional Medical Flashcards

 


 

Cards

Term

 

 

 

HIV-1 and HIV-2

Definition

V: Retroviridae family

  • HIV-2 is less common and milder
  • Transmitted through body fluids
  • Modes of transmission: sex, IDU, MTC, breastfeeding
  • Destoys immune cells like CD4+ T-cells
Term

 

 

 

AIDS

Definition
  • HIV infection + onset of opportunistic infections (OI) = AIDS
  • Common OIs: TB, chronic diarrhea, chronic pneumonia (PCP Pneumocystis carinii pneumonia), fungal like Cryptococcus and thrush, Kaposi's sarcoma
  • Cannot 'catch' AIDS, syndrome not an infection
  • Symptoms appear as CD4 cell counts decrease and HIV viral counts increase
Term

 

 

 

Stages of infection

Definition
  • Primary infection: 'flu-like' symptoms for a few weeks after infection
  • Stage 1 and 2: no symptoms or mild symptoms
  • Stage 3: weight loss and onset of OIs
  • Stage 4: (AIDS) serious OIs, continued weight loss, CD4 count <200 particles per mm3
Term

 

 

 

ARVs/HAART

Definition
  • ARV-Antiretroviral drug
  • HAART-Highly Active Antiretroviral Therapy
  • Prolongs duration of time between infection and onset of clinical AIDS and duration of life after onset of AIDS
  • Not a cure, just reduces viral load
  • Millions would benefit but do not have access to HAART
Term

 

 

 

History of the Epidemic

Definition

 

1981: first identified in homosexual men in the US

1990: 10 million people with HIV worldwide

1995: 20 million

2000: >30 million

2005: ~40 million

2006: revised estimate - ~33million

 

Term

 

 

 

HIV in Sub-Saharan Africa

Definition
  • 10% of world's population but >60% of HIV cases
  • 25 million infected, 2 million deaths per year
  • >6% of adults have HIV; >30% in some countries
  • Highest in young women and urban residents
  • AIDS orphan: at least one parent lost to AIDS
Term

 

 

 

Asia/Oceania

Definition
  • Adult prevalence 2%; >8 million people; >60% in India
  • Modes of transmission: IDU, paid sex
  • New infections in married women by husbands
  • HIV/AIDS education is limited
Term

 

 

 

Rest of the World

Definition

 

  • Increasing in eastern Europe due to IDU and paid sex
  • Low prevalence in Middle East and North Africa
  • 2 million people with HIV in South America and the Caribbean
  • 2 million in North America and western/central Europe
Term

 

 

 

High Risk Groups

Definition
  • Sex workers
  • Men who have sex with men
  • IDUs
  • Prisoners
  • People who do not think they are at risk, elderly
  • Women
    • Biologically (thin vaginal wall) and socially vulnerable
  • MTC transmission
    • Pregnancy, birth process, breastfeeding
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