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5) CH 18 Adrenergic
pharmacology fscj 2011
25
Nursing
Undergraduate 3
11/25/2011

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Term
adrenergic agonists drug class
Definition
(sympathomimetics or adrenomimetics
Term
adrenergic blockers drug class
Definition
(sympatholytics or adrenolytics
Term
Drugs that stimulate the sympathetic nervous system are called
Definition
adrenergics, adrenergic agonists, sympathomimetics, or adrenomimetics
Term
where are adrenergic receptor sites located
Definition
cells of muscles, such as the heart, bronchiole walls, gastrointestinal (GI) tract, urinary bladder, and ciliary muscle of the eye
Term
The alpha-adrenergic receptors are located in
Definition
in the vascular tissues (vessels) of muscles.
Term
. When the alpha1 receptor is stimulated, the arterioles and venules constrict.. which does what?
Definition
increases peripheral resistance and blood return to the heart.
Term
Stimulation of the sympathetic nervous system or use of sympathomimetic (adrenergic agonist) drugs can cause what body reactions
Definition
cause the pupils and bronchioles to dilate; heart rate to increase; blood vessels to constrict; and muscles of the gastrointestinal tract, bladder, and uterus to relax, thereby decreasing contractions.
Term
When the alpha1 receptor is stimulated, the arterioles and venules ....
Definition
constrict
Term
adrenergic blockers work in 2 ways
Definition
they block the effects of the neurotransmitter either directly by occupying the receptors or indirectly by inhibiting the release of the neurotransmitters norepinephrine and epinephrine.
Term
Determine client's health history. Most adrenergic agonists are contraindicated if client has
Definition
cardiac dysrhythmias, narrow-angle glaucoma, or cardiogenic shock.
Term
1. For the client taking epinephrine, the nurse realizes there is a possible drug interaction with which drug?

a. albuterol (Proventil)

b. metoprolol (Lopressor)

c. bethanechol (Urecholine)

d. tolterodine tartrate (Detrol)
Definition
B
Term
2. The nurse will monitor the client taking albuterol (Proventil) for which condition?

a. Palpitations

b. Hypoglycemia

c. Bronchospasm

d. Uterine contractions
Definition
A
Term
3. A client is prescribed metoprolol (Lopressor) to treat hypertension. It is important for the nurse to monitor the client for which condition?

a. Bradycardia

b. Hypertension

c. Ankle edema

d. Decreased respirations
Definition
A
Term
3. A client is prescribed metoprolol (Lopressor) to treat hypertension. It is important for the nurse to monitor the client for which condition?

a. Bradycardia

b. Hypertension

c. Ankle edema

d. Decreased respirations
Definition
C
Term
5. The nurse realizes that beta1 receptor stimulation is differentiated from beta2 stimulation in that stimulation of beta1 receptors leads to which condition?

a. Increased bronchodilation

b. Decreased uterine contractility

c. Increased myocardial contractility

d. Decreased blood flow to skeletal muscles
Definition
C
Term
6. A client is given epinephrine (Adrenalin), an adrenergic agonist (sympathomimetic). The nurse should monitor the client for which condition?

a. Decreased pulse

b. Pupil constriction

c. Bronchial constriction

d. Increased blood pressure
Definition
D
Term
7. The nurse is administering atenolol (Tenormin) to a client. Which concurrent drug does the nurse expect to most likely cause an interaction?

a. ginseng herb

b. An NSAID, such as aspirin

c. methyldopa (Aldomet)

d. haloperidol (Haldol)
Definition
B
Term
three sympatholytic receptors
Definition
alpha1, beta1, and beta2.
Term
Drugs that block the effects of the adrenergic neurotransmitter are called
Definition
sympatholytics
Term
adrenergic agonists are called
Definition
sympathomimetic
Term
drugs that stimulate adrenergic receptors are called
Definition
sympathomimetic
Term
Ephedrine is an example of a mixed-acting
Definition
sympathomimetic
Term
the chemical structures of a substance (either endogenous or synthetic) that can produce a sympathomimetic response.
Definition
Catecholamines
Term
Examples of endogenous catecholamines are
Definition
epinephrine, norepinephrine, and dopamine.
Term
examples of sympathomimetic drug responces
Definition
increase in blood pressure, pupil dilation, increase in heart rate (tachycardia), and bronchodilation.
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