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4) CH 30
pharmacology fscj 2011
28
Nursing
Undergraduate 3
10/26/2011

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Cards

Term
Macrolides are:
Definition
broad-spectrum antibiotics
Term
Macrolides examples
Definition
azithromycin (Zithromax), clarithromycin (Biaxin), and erythromycin (E-Mycin),
Term
At low to moderate drug doses, macrolides have a _______ effect
Definition
bacteriostatic
Term
ith high drug doses, macrolides effect is _____.
Definition
bactericidal
Term
Gastric acid destroys erythromycin in the stomach; therefore _________ are added to erythromycin to slow down dissolution
Definition
acid-resistant salts
Term
adverse reactions to macrolides include
Definition
Hepatotoxicity
Term
all macrolide drug names end in:
Definition
mycin
Term
Tetracycline in combination with metronidazole and bismuth subsalicylate is useful in treating
Definition
Helicobacter pylori, a bacterium in the stomach that can cause a peptic ulcer.
Term
oral and topical tetracycline has been used to treat
Definition
severe acne vulgaris.
Term
Tetracyclines should not be taken with
Definition
magnesium and aluminum antacid preparations, milk products containing calcium, or iron-containing drugs, because these substances bind with tetracycline and prevent absorption of the drug.
Term
Adverse Reactions of tetracyclines
Definition
Photosensitivity, Nephrotoxicity ,superinfection
Term
do not take tetracycline if you are ____
Definition
pregnant!!
Term
Aminoglycosides Action
Definition
Inhibit bacterial protein synthesis
Term
Aminoglycosides examples
Definition
Streptomycin
Gentamicin (Garamycin)
Kanamycin (Kantrex)
Tobramycin (Nebcin
Term
Aminoglycosides Side effects/adverse reactions
Definition
Photosensitivity
Superinfection
Ototoxicity
Nephrotoxicity
Term
Aminoglycosides IV administration
Definition
mix with 100ml bag given over 1 hr.
Term
Aminoglycosides Nursing interventions
Definition
Check C&S.
Monitor renal function, hearing loss.
Warn client to use sunblock.
Monitor for superinfection.
Monitor peak and trough levels
Term
Fluoroquinolones action
Definition
Interfere with enzyme DNA gyrase
Fight gram + and –
Broad spectrum: bactericidal
Term
Fluoroquinolones treatments
Definition
Streptococcus pneumoniae, Salmonella
Bone and joint infections
Bronchitis and pneumonia
Gastroenteritis
UTI, gonorrhea
Term
Fluoroquinolones Nursing interventions
Definition
Check C&S.
Infuse IV over 60 to 90 minutes.
Increase fluid intake to more than 2000 mL/d.
Tell client to avoid caffeine.
Check for superinfection.
Term
Fluoroquinolones Drug interactions
Definition
Antacids decrease absorption rate.
Levofloxacin increases effect of oral hypoglycemics, theophylline, caffeine.
Term
1. A client is taking azithromycin (Zithromax). The nurse should apply which interventions? (Select all that apply.)

a. Monitor periodic liver function tests.

b. Dilute with 50 mL for IV administration.

c. Tell the client to report any hearing loss.

d. Instruct the client to report evidence of superinfection.

e. Teach the client to take oral drug 1 hour a.c. or 2 hours p.c.

f. Avoid antacids from 2 hours prior to 2 hours after azithromycin administration.
Definition
A,C,D,E,F
Term
2. The nurse closely monitors the client taking lincosamides for which serious adverse effect?

a. Seizures

b. Ototoxicity

c. Hepatotoxicity

d. Pseudomembranous colitis
Definition
D
Term
3. The nurse enters a client's room to find that his heart rate is 120, his BP is 70/50, and he is flushed. Vancomycin (Vancocin) is running IVPB. The nurse interprets this as a severe adverse effect of “red man syndrome.” What should the nurse do?

a. Stop the infusion and call the laboratory.

b. Reduce the infusion to 10 mg/min.

c. Encourage the client to drink more oral fluids up to 2 L/day.

d. Report to health care provider the onset of Stevens-Johnson syndrome.
Definition
B
Term
4. The nurse is administering tetracycline (Vibramycin) to a client. Which would be appropriate teaching?

a. Take sunscreen precautions when at the beach.

b. Take an antacid or milk with the drug to prevent severe GI distress.

c. Obtain frequent hearing tests for early detection of hearing loss.

d. Obtain frequent eye checkups for early detection of retinal damage.
Definition
A
Term
5. A client is taking levofloxacin (Levaquin). The nurse knows that which is true regarding this drug?

a. Administered IV only

b. May cause hypertension

c. Classified as an aminoglycoside

d. Adverse reaction includes dysrhythmias
Definition
D
Term
6. What should the nurse include when teaching a client about gentamicin (Garamycin)? (Select all that apply.)

a. Client should report any hearing loss.

b. Client must use sunscreen.

c. IV gentamicin will be given over 20 minutes.

d. Client will be monitored for mouth ulcers and vaginitis.

e. Peak levels will be drawn 30 minutes prior to IV dose.

f. Client should increase fluid intake.
Definition
A,B,D,F
Term
7. The nurse acknowledges which nursing intervention(s) for the client taking ciprofloxacin (Cipro)? (Select all that apply.)

a. Obtain culture prior to drug administration.

b. Tell the client to avoid taking Cipro with antacids.

c. Monitor the client for hearing loss.

d. Encourage fluids to prevent crystalluria.

e. Infuse IV Cipro over 60 minutes.

f. Monitor blood glucose, as Cipro can decrease effects of oral hypoglycemic.
Definition
A,B,C,D,E
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