Term
| Pathway of vessels to kidneys |
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Definition
| Aorta->Renal Artery->Afferent arteriole->Glomerular capillaries->efferent arteriole->peritubular capillaries->Renal Vein->IVC |
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Term
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Definition
| Goes from hilum of the kidney down to bladder |
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Term
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Definition
1. Glomeruli (filtration)
2. Tubule (reabsorption/secretion)
3. Blood vessels |
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Term
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Definition
1. Superficial
2. Juxtamedullary |
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Term
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Definition
Glomeruli form ultrafiltrate
Tubules modify ultrafiltrate |
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Term
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Definition
Layers:
Filtration barrier
1. Glomerular capillary endothelial cells
2. Glomerular Basement Membrane
3. Podocytes (forms Bowman's Capsule)
Supported by mesangeal cells.
BM and podocytes don't cover all of the capillaries, some parts covered by the mesangeum. |
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Term
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Definition
Composed of podocytes.
One end covers the glomerular capillaries, other end forms tubules. |
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Term
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Definition
| Have foot processes that interdigitate with other podocyte foot processes to form a fine meshwork used for filtration, surrounds cells with pores. |
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Term
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Definition
Used for reabsorption or secretion of ultrafiltrate components.
Hollow tube made up of a single layer of epithelial cells.
Inside surface=luminal/apical
Outside surface=basolateral/peritubular |
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Term
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Definition
Products must be outside body and measured directly from urine.
Excretion=Amount filtrated-amount reabsorbed+amount secreted. |
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Term
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Definition
1. Proximal Nephron (Convoluted and straight)
2. Loop of Henle (thin descending, thin ascending, thick ascending)
3. Distal nephron (Distal convoluted tubule, connecting duct, collecting tubule)
3. |
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Term
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Definition
1st part of renal tubule.
Consists of convoluted and then straight tubules.
Used for bulk reabsorption of water and solutes. |
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Term
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Definition
2nd part of renal tubule
1. Thin descending limb
2. Thin ascending limb
3. Thick ascending limb
Used for dilution or concentration of urine through water. |
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Term
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Definition
Last part of the renal tubule, used for fine tuning of urine composition.
Has
1. Distal convoluted tubule
2. Connecting duct
3. Collecting tubule |
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Term
| Requirements for transepithelial transport |
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Definition
1. Driving force (pressure, EC gradient)
2. Permeability (size of transport surface, surface area, number/ type/selectivity of transporters) |
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Term
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Definition
| Transepithelial, can be transcellular or paracellular. |
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