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407 exam3.7
n/a
18
Biology
Undergraduate 4
04/08/2014

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Term
nictotine
Definition
impacts fetal growth- intrauterine growth restriction, brain dev.
decreased blood to infant
Term
retinoic acid/accutane
Definition
craniofacial abnormal
Term
neural tube developes --
Neural tube defect results from
Definition
22-28 days pregnant (before mom knows)
neural plate disrupted
Term
nural tube doesn't close:
cranial region
spine
Definition
cranial- anencephaly
spine- spina bifida
Term
neural tube defect caused by
Definition
impaired folate statue caused by genetic mutation in folate metabolism or inadequate intake
Term
spina bifida babies have:
Definition
paralysis
impaired bladder control
club feet
mental impairment
Term
anencephaly
Definition
missing skull
almost always fatal
Term
neural tube defects diet or genetic
Definition
both
abnormal gene code for enzyme for folate metabolism
Term
Neural tube defect can be detected by 3 tests:
Definition
maternal serum alpha fetoprotein
high resolution ultrasound
amniocentesis
Term
maternal serum alpha fetoprotein
Definition
increased levels could indicate multiple fetuses, wrong gest age, NTD
Term
Gestational HTN
Definition
High BP develops after 20wks goes away after delivery
Term
Both HTN can lead to -- which is --
Definition
pre eclampsia = high BP +protein in urine
Term
eclampsia
Definition
seizures due to high BP= brain injury, fetus no O2, damaged placenta
Term
risk factors for gestational HTN
Definition
1st preg
age <15 or >35
family
obesity
Term
recent evidence for cause of eclampsia
Definition
chorionic villi faulty implant, arteries are small reducing blood thru placenta causing BP to rise
Term
gestational diabtetes
Definition
hormones cause mom tissue to be kinda insulin resistant
less glucose taken up by mom= more for baby
2nd-3rd trimester
Term
gestational diabetes risk to baby
Definition
macrosomia at birth
increased risk for type 2 and obesity
Term
gestational diabetes risk to mom
Definition
GD goes away at end of preg
increased risk for type 2, GD in next preg, complications in delivery (c section)
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