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3rd week of development
3rd week of human development
30
Science
Undergraduate 4
01/22/2009

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Term
Major Events of 3rd Week
Definition
1.Craniocaudal folding caused by growth of CNS 2. Lateral folding caused by growth of somites, amnion, and other components of lateral body wall. 3. craniocaudal folding and lateral folding change shape of embryo from a two-dimensional disk to a 3-dimensional cylinder.
Term
Gastrulation
Definition
process establishes three definitive germ layers of embryo, thereby forming a trilaminar embryonic disk by day 21 of development. first indication primitive streak
Term
Ectoderm
Definition
gives rise to epidermis, the central and peripheral nervous systems, the retina of eye.
Term
Endoderm
Definition
source of epithelial linings of respiratory passages and GI tract, glands into GI tract, glandular cells of associated organs liver, pancreas.
Term
Mesoderm
Definition
gives rise to smooth muscular coats, connective tissues, vessels associated with tissues and organs, forms most of cardiovascular system. blood cells bone marrow, skeleton, striated muscle
Term
Primitive Streak
Definition
first sign of gastrulation consists of: primitive groove, node, pit. composed of epiblast.
Term
Mesenchyme
Definition
cells leave the deep surface of Primitive groove and form loose network of embryonic tissue called mesenchyme or mesoblast, which forms the intraembryonic mesoderm
Term
Embryonic endoderm
Definition
some cells of epiblast displace hypoblast forming embryonic endoderm in roof of yolk sac.
Term
Cloacal membrane
Definition
caudal to the primitive streak and future site of anus, where epiblast and hypoblast cells are fused.
Term
Epiblast products
Definition
ectoderm, intraembryonic mesoderm, and endoderm of trilaminar embryonic disk.
Term
Intraembryonic Mesoderm
Definition
germ layer that orms during week 3 in contrast to extraembryonic mesoderm, which formed during week 2.
Term
Intermediate Mesoderm
Definition
connects paraxial mesoderm and lateral mesoderm. forms longitudinal dorsal ridge known as urogenital ridge, involved in future kidney and gonad formation.
Term
Lateral mesoderm
Definition
thin plate mesoderm in which intraembryonic coelem forms, dividing lateral mesoderm into 2 layers: a. intraembryonic somatic mesoderm b.intraembryonic visceral mesoderm
Term
Notochod functions
Definition
induces overlying embryonic ectoderm to thicken and from neural plate. induces formation of vertebral bodies. forms nucleus pulposus of each intervertebral disk in a newborn.
Term
Cardiogenic mesoderm
Definition
where primordium of the heart begins to develop
Term
Neural Plate
Definition
Primordium of CNS. developing notochord induces overlying embryonic ectoderm to thicken and form neural plate
Term
Neural plate
Definition
as notochord develops embryonic ectoderm thickens to form an elongated plate of thickened epithelial cells.
Term
Neuroectodermal cells
Definition
lie along crest of each neural fold and form neural crest which give rise to spinal ganglia and the ganglia of autonomic nervous system
Term
Neural Crest derivatives
Definition
CN ganglia V,VII,IX,X; meningial layers, schwann cells, cells of suprarenal medulla, several skeletal and muscular components in head.
Term
Somites
Definition
arise from division of paraxial mesoderm that pair into cuboidal bodies.
Term
Angiogenesis
Definition
blood vessel formation begins in extraembryonic mesoderm of yolk sac connecting stalk and chorion.
Term
Blood Vessel development
Definition
develop from endothelial cells as the vessels develop in walls of yolk sac and allantois at end of third week.
Term
Blood Formation
Definition
Blood formation does not begin until the fifth week and occurs in embryonic mesenchyme, the liver, spleen, bone marrow, and lymph nodes.
Term
Primordial Cardiovascular System
Definition
forms from mesenchymal cells in cardiogenic area, by formaing a primitive heart tube. form primordial cardiovascular system. cardiovascular system first functional system.
Term
Cardiogenic mesoderm
Definition
two endocardial heart tubes arise from cardiogenic mesoderm. these fuse to form primitive heart tube, which develops into endocardium.
Term
Chorionic Sac
Definition
Extraembryonic somatic mesoderm and two layers of trophoblast constitute the chorion.
Term
Chorionic Cavity
Definition
chorion forms the wall of chorionic sac which is area surrounding yolk-sac and the amniotic cavity.
Term
Transvaginal ultrasound
Definition
measures chorionic sac diameter. measurement is valuable for evaluating very early embryonic development and pregnancy outcome.
Term
Chorionic villi
Definition
grow from cytotrophoblast that grow into the syncytiotrophoblast. Thought to be induced by the underlying extraembryonic somatic mesoderm. develop into chorionic villi of placenta.
Term
Beginning of blood flow
Definition
3rd week embyonic blood flows slowly through capillaries in chorionic wall. oxygen & nutrients of mom in intervillous space diffuse through walls of villi and enter embryo's blood. CO2 & waste diffuse from blood in fetal capillaries through wall of villi into maternal blood.
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