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3802
Inflammatory
45
Biology
Undergraduate 1
03/24/2009

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Term
INFLAMMATION
Definition
A protective reaction

Can be caused by nonliving agents i.e. heat, trauma

Always present with infection

Infection occurs only through superimposed evasion of microorganisms It establishes an environment for healing

Term
INFECTION
Definition

Involves invasion of tissue or cells by microorganisms (bacteria, fungi, or viruses)

Always has inflammation present

Often reveals altered lab values ( i.e. WBCs, positive cultures)

Term
Recognizing infection
Definition
Local or systemic
Patient information, clinical appearance (objective and subjective)
Vital signs
Lab values
CBC (Complete Blood Count)
Culture reports
Term
note about recognizing infection
Definition
Note that in elderly adults typical signs and symptoms may not be present (reduced immune and inflammatory response)
Term
Local infection
Definition
proper care controls the spread and minimizes the illness. pan and tenderness at the wound site
Term
systemic infection
Definition
an infection that affects the entire body instead of just a single organ. can become fatal
Term
Complete Blood Count
Definition
Erythrocytes – RBCs
Leukocytes – WBCs
Thrombocytes –
    platelets
Term
White Blood Cells
Definition
5000-10,000
Term
Neutrophils
Definition
55-70%
“Bands”
Increased in acute supporuative infection, decreased in overwhelming bacterial (older adult)
Term
Eosinophils
Definition
1-4%
increased in parasitic infection
Term
Basophils
Definition
0-1%
normal during infection
Term
Monocytes
Definition
5-10%
increased in protozoal, rickettsial, and tuberculosis infections
Term
Lymphocytes
Definition
20-40%
increased in chronic bacterial and viral infection, decreased in sepsis
Term
leukocytes
Definition
an increase of number of circulating WBCs, is the body's response to WBCs leaving blood vessels.
“shift to the left”
Term
Leukopenia
Definition
is a decrease in the number of circulating white blood cells (leukocytes) in the blood. As the principal function of white cells is to combat infection, a decrease in the number of these cells can place patients at increased risk for infection.
Term
Signs of inflammation
Definition
Swelling
Redness --     hyperemia
Heat
Pain/Tenderness
Loss of Function
Term
Stages of Inflammatory Response
Definition
Vascular and cellular
Inflammatory exudates
Tissue repair
Term
Vascular and cellular
Definition
response to infection
Term
Inflammatory exudates
Definition
formation of fluid and cells that are discharged from cells or blood vessels, e.g, pus or serum
Term
Tissue repair
Definition
repair of tissue
Term
vascular response
Definition
Injury occurs->vasodilation->tissue necrosis->histamine, bradykinin, prostaglandin->increased permeability small vessels (edema)->fluid, protein, cells
Term
Acute
Definition

heals in 2-3 wks *no residual damageneutrophils predominant.

Subacute is basically the same but last longer   i.e. endocarditis   

Term
chain of infection
Definition
an infectrions agent or pathogen.
a reservoir or source for pathogen growth.
a portal of exit from the reservoir.
a mode of transmission.
a portal of entry to a host.
subsceptible host.
Term
Chronic
Definition
*lasts for weeks, months or years
        *persistence = injured tissues
        *predominant cells are lymphs,               macrophages
        *debilitation  leads to decreased               immunity
          i.e. rheumatoid arthritis, TB
Term
NOSOCOMIAL INFECTIONS
Definition
Iatrogenic, exogenous, endogenous

    * Hospital acquired
    * Primarily transmitted by health             care workers

#1 CAUSE = improper handwashing
Term
Iatrogenic
Definition
are a type of nosocomial infection resulting from a diagnostic or therapeutic response
Term
exogenous
Definition
arises from microorgansisms external to the individual that do not exist as normal flora.
Term
endogenous infection
Definition
can occur when part of the client's flora becomes altered and an overgrowth results.
Term
Sites for Nosocomial Infections
Definition
Urinary Tract
Surgical Wounds
Respiratory Tract
Blood stream
Term
MEDICAL
Definition
“Clean” technique
Reduces presence            
Microorganisms
Prevents spread from place to person
Term
SURGICAL
Definition
“Sterile” technique
Eliminates all microorganisms, pathogens, spores.
Requires sterile field and equipment (O.R. and during invasive procedures)
Term
Role of Nurse in Infection Control
Definition
Assess patient’s defense mechanisms, susceptibility and knowledge of infections
Term
Assess……
Definition
Age
Nutritional status
Stress
Disease process
Medical therapy
Clinical appearance
Laboratory data
Term
nursing diagnoses
Definition
Risk for infection
Imbalanced nutrition
Impaired oral mucus membrane
Risk for impaired skin integrity
Social isolation
Term
Patient Goals
Definition
Prevent exposure to infectious organisms
Control or reduce extent of infection
Maintain resistance to infection
Educate patient/family about infection control
Term
Nursing Plans-Health Promotion
Definition
Strengthen defenses against infection
Nutritional support
Rest
Vaccines
Term
Nursing Plans-Acute Care Measures
Definition
Administer antibiotics
Prevent complications of fever
Support integrity of healing wounds
Support patient’s defense mechanisms
Term
Control/eliminate infectious agents
Definition
Medical asepsis
Administer medications
Disinfection/sterilization
Term
Control/eliminate reservoirs
Definition
Dressing changes    
Apply principles of wound care
Discard contaminated articles
Incontinent care
Term
Control portals of exit
Definition
Careful handling of body fluids
Careful handling of linen
Term
Control transmission
Definition
Consistent handwashing
Cleaning of equipment and environment
Do not share bedpans, urinals, etc
Teach pts & family about handwashing
Term
Control the portal of entry
Definition
Maintain skin integrity
Avoid wrinkles in linen
Maintain integrity of mucus membranes
Maintain closed drainage systems
Term
The Susceptible Host
Definition
Breaks in skin and mucous membranes (baths, lubrication, oral care)
Invasive devices
Stasis of body fluids (positioning, activity)
Inadequate nutrition, dehydration
Stress
Immune system dysfunction
Coexisting medical problems
Drug therapy
Term
Protection of Susceptive Host Isolation Procedures
Definition
Standard Precautions
Transmission Categories
Airborne precautionsa
Droplet precautions
Contact precautions
Protective environment
Psychological Effects of Isolation
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