Term
What problem does the G3P shuttle solve? |
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Definition
Reoxidizing cystolic NADH back to cystolic NAD+ aerobically bc you cant use lactate DH since pyruvate enters TCA and is unavaiable. The inner membrane is impermeable to NAD which controls the NAD ratio. *The key is that we need to re-oxidize NADH aerobically |
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Term
What solution does the G3P give? |
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Definition
Cystolic NADH is reoxidized to NAD+ aerobical via an indirect transfer of e- via G3P shuttle. 2 e- are transported across the membrane (since NADH itself can't be) |
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Term
go thru the steps of the G3P shuttle |
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Definition
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Term
What is the p/o ratio of cystolic NADH |
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Definition
1.5 ATP bc it enters at complex 3 (complex 3+4=6H+ =1.5 ATP) |
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Term
Atp produced by glycolysis and G3P shuttle= |
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Definition
2 ATP glycolysis +1.5 ATP shuttle |
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Term
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Definition
30 **know how to get this number with each step!!! |
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Term
Where does atp come from for 100m dash vs marathon |
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Definition
glycolysis- dash TCA-marathon (glucose will be oxidized to CO2 aerobically) |
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Term
Why use anaerobic glycolysis for a dash> |
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Definition
bc rate of rxn in glycolysis is much faster to go to lactate then oxidation/respiration. About 2x faster=6x more atp. downside is lactate = fatigue |
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