Term
| Prion proteins are found in -- the normal function is-- |
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Definition
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Term
| Neurologic disorders arise |
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Definition
| when the conformation of prion proteins changes from a low amount of beta sheet to a larger amount of beta sheet. |
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Term
| the abnormal prion proteins (termed PrPSc for prion protein scrapie-type) |
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Definition
| aggregate and also cause conversion of more normal prion proteins (termed PrPC, C for cellular) to PrPSc |
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Term
| Abnormal prion proteins are the causitive agents of several devastating neurologic diseases, including |
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Definition
| scrapie in sheep and goats, chronic wasting disease in deer and elk, kuru in cannibals, mad cow disease, and Creuzfeldt-Jacob disease in humans |
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Term
| term prion coin in -- by -- |
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Definition
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