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2nd Patho Exam
2nd Patho Exam
47
Nursing
Undergraduate 3
02/27/2011

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Cards

Term
What are the values for underweight, normal, overweight and obese?
Definition
underweight (<18.5). Normal (18.5 - 24.9). Overweight (25 - 29.9) Obese ( > 30)
Term
What does primary and secondary obesity result from?
Definition
Primary (Caloric intake > metabolic demand)
Secondary (Result form another condition)
Term
What is abnormal waist sizes in Men and Women?
Definition
M ( >40 in.)
W ( >35 in.)
Term
What is Gynoid and Android obesity? and which is the most toxic
Definition
Gynoid = Gluteofemoral adipose tissue accumulation
Android = Abdominal adipose tissue
Most toxic = Android
Term
What is the drug therapy for obese people?
Definition
Orlistat (Alli) = Prevents body from absorbing fat.
Term
What is Metabolic syndrome and what are the risk factors?
Definition
Metabolic Syndrome = Collection of risk factors that increase risk of developing heart disease or diabetes. Must have 3 of the following: Increased waist circumference ( >40 Men, >35 Women), Increased triglycerides (>150), Decreased HDL (<40 Men, <50 Women), Increased BP (>130/85), Increased fasting glucose (>100)
Term
What are the Antidysrthmic drugs for Atrial fibrillation?
Definition
Amiodarone (Cordarone), Dofetilide (Tikosyn)
Term
What are Stenosis, Regurgitation and Prolapse?
Definition
Stenosis = Valve fails to open completely (think stiffness)
Regurgitation = Valve fails to close completely
Prolapse = Valve flops backward into the atrium during ventricular systole
Term
What is the short term drug for a STEMI to dissolve a clot?
Definition
Alteplase (tPA)
Term
What are the long term drugs for a STEMI?
Definition
Beta-Blocker, ACE or ARB for Left ventricular systolic dysfunction, Antiplatelet drug or Anticoagulant, Statin if LDL > 100.
Term
What is Ejection Fraction?
Definition
Amt. of blood ejected from the ventricle (Stroke volume) DIVIDED BY Amt. of blood in the ventricle prior to ejection (end-diastolic volume)
Term
What is Systolic HF?
Definition
Impaired contraction or pumping
Term
What is Diastolic HF?
Definition
Impaired relaxation or filling
Term
What are the Stages of HF?
Definition
1) Asymptomatic
2) Symptomatic with moderate exertion
3) Symptomatic with minimal exertion
4) Symptomatic with rest
Term
What are the drugs for HF patients?
Definition
Diuretics - Furosemide (Lasix)
RAAS Inhibitors - ACE and ARBS, and Aldosterone Antagonists = Spironolactone (Aldactone)
Beta-Blockers - Carvedilol (Coreg)
and Digitalis (Digoxin)
Term
What does metoprolol (Lopressor) do?
Definition
Beta-Blocker. Inhibits SNS activity, reduces HR, BP and Contractility. Used with ACS, STEMI, HF, A-fib. Hold if SBP <100 or HR <60.
Term
What does captopril (Capoten) do?
Definition
ACE inhibitor. Reduces cardiac remodeling. May get the ACE cough.
Term
What does losartan (Cozaar) do?
Definition
it's an ARB. Used in HF patients who can't tolerate ACE's d/t the ACE cough.
Term
When does irreversible tissue injury occur?
Definition
30 min - 4 hr.
Term
When does tissue necrosis begin?
Definition
by 4 hours
Term
When is necrotic tissue cleared away?
Definition
Necrotic tissue is cleared away by 1-2 weeks.
Term
When does tough fibrous scar tissue replace necrotic tissue?
Definition
tough fibrous scar tissue replaces necrotic tissue by 6 weeks.
Term
what is the importance of adenosine triphosphate (ATP)?
Definition
ATP is the energy source for our cells adn for our heart muscle, heart muscle cells cant store ATP, so the heart must continously make ATP, the way it makes it is with oxygen, so if stop oxygen to the heart, then it can't make ATP.
Term
What is the electrical pathway of the heart?
Definition
1. An electrical impulse from the SA node spreads quickly among the right and left atria
2. The impulse arrives at the AV node where it slows down (this lets the atria finish their contraction)
3. The impulse travels rapidly through the bundle of His, carried by Purkinjie Fibers.
4. The bundle of His divides into right and left bundle branches.
5. The Purkinjie fibers continue to rapidly carry the impulse through the ventricles so the ventricles can contract.
Term
What does the pulmonic valve do?
Definition
pulmonic valve = directs blood flow between the right ventricle and pulmonary artery
Term
What does the aortic valve do?
Definition
aortic valve = directs blood flow between the left ventricle and aorta
Term
What does the mitral valve do?
Definition
mitral valve = directs blood flow from the left atrium to left ventricle
Term
what does the tricuspid valve do?
Definition
tricuspid valve = directs blood flow from right atrium to right ventricle
Term
What is the myocardium?
Definition
myocardium = cardiac muscle layer
Term
What is the endocardium?
Definition
endocardium = layer of epithelial cells that line the heart chambers and valves
Term
what is the pericardium?
Definition
pericardium = two layers that envelop the heart like a sac
Term
what is the pericardial space?
Definition
pericardial space = space between the visceral and parietal pericardial layers.
Term
What drug would you give to fix the rhythm of A-fibrillation?
Definition
amiodarone (Cordarone) or dofetilide (Tikosyn)
Term
What drug would you give to fix the rate of A-fibrillation?
Definition
dilitiazem (Cardizem) or metoprolol (Lopressor)
Term
what are local and systemic manifestations of infective endocarditis?
Definition
Local - valve damage, heart murmur
Systemic - fever, chills. Flu like symptoms, positive blood cultures, emboli.
Term
what are complications of endocarditis?
Definition
embolus, valvular insufficiency, myocardial abscess
Term
What is the Acute Pericarditis Triad (PEC)?
Definition
P = Pericardial Friction Rub
E = ECG Changes
C = Chest Pain
Term
What are the two most common dysfunctional valves in valvular disease?
Definition
aortic and mitral valves
Term
What do you hear when you auscultate a heart with valvular disease?
Definition
Murmur
Term
What is a saccular aneurysm?
Definition
Saccular (balloon shaped), involves only one part of circumference, wide neck
Term
What is a Berry aneurysm?
Definition
A subtype of saccular aneurysms, small neck, located at bifurcation. Common location = Circle of willis.
Term
What is a fusiform aneurysm?
Definition
Entire circumference of vessel, gradual/progressive dilatation, potentially extensive involvement.
Term
what are the clinical manifestations of a Thoracic Aneurysm?
Definition
Think upper Signs and symptoms r/t voice and airway, expanding and pressing on trachea and esophagus.
Pain (substernal, back, neck)
Breathing (Dyspnea, stridor, brassy cough)
Other (hoarseness, difficulty swallowing)
Term
what are the clinical manifestations of a Abdominal Aneurysm?
Definition
Usually asymptomatic, palpation of pulsating mass (by 4 cm), Pain (mild to severe, mid-abdomen or back). Possible thrombus formation (whenever structural problem with vessel it causes turbulent blood flow and turbulent blood flow leads to a clot development, b/c kind of have stagnating blood there.
Term
What do drug do you give for an aneurysm?
Definition
a Beta-Blocker.
Term
What are the stages 0-4 of urologic cancers?
Definition
Stage 0 (in citu) = cells found in inner bladder surface
Stage 1 (limited) = has penetrated inner lining but not muscle
Stage 2 (Spreading) = spread to muscle layer
Stage 3 (Spread beyond muscle to outer layer
Stage 4 (mestastes) = Spread towards abdominal or pelvic wall
Term
What is the drug for intermittent claudication?
Definition
cilostazol (Pletal)
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