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216
Class. of Major Bacteria grps in Disease
72
Microbiology
Undergraduate 2
04/11/2011

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Term
Spirochetes
Definition
helical, flexible; motile-periplas flagellum
ex) Treponemia Pellidum - Syphillis & Barrelia burgdorferi - Lyme's disease
Term
aerobic/microaerophilic helical or vibroid
Definition
gram negative, comma-shaped to spiral; typically motile & flagella
ex) Compyloberter jejuni - food bourne diarheal, spiral & Helicobacter pylori - peptic ulcers, spiral ; Vibrio cholerae - comma-shaped
Term
- ; rods & cocci
Definition
G _ & aerobic ___________; everywhere in nature
ex) Legionella pneumophila - pneunomia like ; Burdetella pertussis - whopping cough ; Neisseria meningiditis ; Neisseria gonorhoue - gonorrhea ; Psuedamonas aeruginosa - infect of burn wounds
Term
facutatively ; -
Definition
____________anerobic G__ rods
if motile=peritrichous flagellum; cmnly found in intestinal tract & environment
ex) Escherichia coli - UTI, pneunomia ; Salmonella - food-bourne, typhoid fever ; Shigella - lack of fl from diarrhea ; Enterobacter aerogenes - UTI, breathing tubes (opportunistic)
Term
anaerobic ; -
Definition
________ g___ rods
(straight, curved, helical) motile/immotile; live in intestinal track of humans/animals
ex)Fusobacterium - oral cavity ; Bacteroides - opportunistic
Term
cocci
Definition
anerobic g- _____; pairs in mouth, intestine, vagina
ex) Veillonella - dental caries, gingivitis
Term
Rickettsias & Chlamydias
Definition
very small G-, usually rods; typically req host for replication
Term
Rickettsias
Definition
req arthroped & vertebrate host
ex) R Rickettsii - Rocky Mntn Spotted fever ; R prowazecki & R typhi - typhus (tick bourne)
Term
Chlamydias
Definition
uniq lifestyle (reticulate body --> elementary body)
ex) C trachomatis - eye infect ; C pneunomia ; C psittaci - original host
Term
mycoplasmas & ureaplasmas
Definition
pleomorphic; resistant to Penicillin, cephaeospirins, yanconycin & any other antibiotic that inhibs cell wall synthesis; smallest fine-bacteria
ex) M pneunomia - typical pneunomia ; M genitalium - urithritis ; M haminis - pelvic inflam
Term
+ cocci
Definition
G_ _____ ; anaerobe & aerobe
ex) Micrococcus ; Staph aureus ; Strep pyogens ; Strep pneunomia ; Staph epideimidis (opportunistic)
Term
Micrococcus
Definition
normally found on skim (forms tetrad); not harmful on skim, only if infection goes inside; opportunistic ; MRSA
Term
Strep pyogens
Definition
strep throat, scarlet fever, & empentigo
Term
+
Definition
endospore forming; g_ rods & cocci; highest level of disinfection & sterilization; antibiotics will stop new toxins in Clostridiums
ex) Baccilus anthracis ; B cereus - food poisoning ; Clostridium tetani ; C botulinum ; C perfringens ; C difficile
Term
tetanis
Definition
all muscles contract at once @ a point (spastic paralysis)
Term
Clostridium tetani
Definition
causes tentani ; "lock jaw" ; deep wound created by dirty environment
Term
G+ & R- no endospores
Definition
oblig & fac anaerobes
ex) Listeria mytocytogenes - listeriosis (why pregnant women shouldn't eat raw meats = mental retardation, spontaneous abortion)
Term
+
Definition
fac anaerobes; unusual g__ rods
ex) Actinomyces - opp., skin, bld, in environemnt ; Carynebacterium diptheriae - dyptheria, blocks breathing ; Proprianibacterium acnes - acne ; Nocardiforms ; Streptomyces - natural source for MOST antibiotics ; Methanogenes - root canal infects.
Term
Streptomyces
Definition
natural source for most antibiotics we use 2day
Term
capsid
Definition
protein shell, encoded by viral genome; helical, icosahedral, complex ; may have spikes
Term
nucleic acid
Definition
inside capside; dsDNA, ssDNA, ssRNA, dsRNA ; linear or circular
Term
virion
Definition
fully established viral particle
Term
envelope
Definition
phospholipid memb surounding nucleocapsids
Term
viral multiplication
Definition
occurs w.i host cell; req host metabolic machines = obligate intracellular parasite
Term
absorption
Definition
1. attach 2 host cell mediated by tail fibers spikes viral glycoproteins embedded in envelope
Term
penetration
Definition
2. virus or nucleocapsid enters host cells, occurs by engulfment or fusion
Term
uncoating
Definition
3. rel of viral NA into host cell
Term
replication
Definition
4. synthesis (viral protein) & replication of virus (NA)
Term
do not
Definition
Viruses that (do/donot?) have envelop are more suseptible to environment
Term
Abortive infection
Definition
VIRAL: virus effects a non-permissable(not appropriate replication of virus) cell; non-productive
Term
Lytic infection
Definition
VIRAL: permissive cell infected replication cycle can be completed; kills host cell
Term
Persistent infection
Definition
VIRAL: permissive cell=cycle complete; if it kills host cell its req a long time (4types:chronic, latent, slow, transforming)
Term
chronic infection
Definition
Type of Persistent:
-very, slow viral production; does not lead to lytic infection
Term
latent infection
Definition
Type of Persistent:
-virus is relatively dormant; no viral synthesis
Term
slow infection
Definition
Type of Persistent:
-virus that has prolong incubation period; disease progression over years, end w/ extensive cell damage & disease (HIV, some Hepatitis)
Term
transforming infection
Definition
Type of Persistent:
-oncogenic virus may/may not be produced; host cells turns cancerous (1. immortal 2. can't control replication)
Term
morphological effects aka. Cytopathic effects
Definition
Host Cell Damage:
-altered cell shape, could detach from tissue, lysis, memb fusion (causes giant cell formation), alter memb permeability
Term
apoptosis
Definition
formation of cell death, "cell suicide", cell implodes
Term
physiological effects
Definition
Host Cell Damage:
-alter cellular activity, changes in immunogenity
Term
Biochemical effects
Definition
Host Cell Damage:
-specifically on metabolism
Term
Genotoxic effects
Definition
Host Cell Damage:
-damage to DNA->mutations->change activities of cell OR cancer OR kill cell
Term
DNA viruses
Definition
viruses w/ DNA genome
Term
adenovirus
Definition
DNA virus:
-able to survive in environment 4 ext. periods; USU, respiratory; might cause conjunctivitis, cystitus, rashes
Term
cystitus
Definition
inflamation of bladder
Term
hepadma virus
Definition
DNA Virus:
-cause hepatitis(animals&humans), have envelope(xtra piece of memb from last infection)
Term
Hep B
Definition
Hepatitis __ is longer lasting
Term
Herpesvirus
Definition
DNA Virus:
-contains HSV I & II, varicella zoster, Epstein Barr virus, Cytomegalovirus, dangerous in children, usually resp., human herpes 6,7,8
Term
1.Papillomavirus & 2.Polyomavirus
Definition
DNA Virus:
-1. causes warts, tied to cervical cancer, easily spread (HPV)
-2. similar
Term
-oma-
Definition
uncontrolled cell generation
Term
Parvovirus
Definition
DNA Virus:
-smallest DNA virus; contagious errythema infectiosum(5th disease, skin rash particularly on face)
Term
Pox virus
Definition
DNA Virus:
-largest DNA virus, incredibly body disfiguring; contained Variola, Molloscum contagiosim, Vacinium
Term
Bunya virus
Definition
RNA Virus:
-Zoonosis; most are transmitted to humans by anthropods; Hantavirus, excreted in mic urine & feces = Hemoragic Pulmonary Syndrome
Term
Zoonosis
Definition
infection in animal but transmitted to human
Term
arthropods
Definition
tics & fleas
Term
Corona virus
Definition
RNA Virus:
-resp & enteric disease; 2nd most cmn cause to cold, SARS
Term
SARS
Definition
severe, acute, resp syndrome
Term
hepatitus viruses
Definition
infect & destroy liver
Term
Orthomyxo virus; dangerous, viralent
Definition
RNA Virus:
-includes inflecting A, B, & C type viruses; significant disease w/ type A & B, C = most _______ & A = most ______
Term
Paramyxo viruses
Definition
Measles, Mumps, resp synctyial virus (RSV)
Term
Picorna virus
Definition
RNA Virus:
-smallest (pico) RNA virus; include entero virus(Polivirus), rhinovirus(most cmn 4 cold)
Term
Rhabdo virus
Definition
RNA Virus:
-rabies bullet ("rhabdo")
Term
Retro virus
Definition
HIV has RNA--(host cell)-->DNA =goes back ("retro)
Term
Reo virus
Definition
RNA Virus:
-resp. enteric orphans virus; Rotavirus
Term
Rota virus
Definition
RNA Virus:
-A Reo virus; is diarrheal, little kids often ahve it, infants need hospitalized for fluids
Term
Toga virus
Definition
RNA Virus:
-infectious arthritis, cephalitis, rashes; Rubivirus-->Rebella
Term
1. Rubivirus; 2. Rebella
Definition
RNA Virus:
-Toga virus; 1. red rash --> 2. agent of German measles
Term
Flavi virus
Definition
RNA Virus:
-yellow fever (tropical), Denque fever(tropical), & Hep C
Term
Hepatitus delta virus, Flavi virus, Hepadna virus
Definition
3 viruses that cause hepatitis?
Term
subviral agents
Definition
all unusual infections agent
Term
viroid
Definition
Subviral Agent:
-genome of single, stranded RNA in circle; plant pathogens
Term
virusoids
Definition
Subviral Agents:
-RNA genomes, replicate in host cell cytoplasm, req host cell already infected w/ helper virus; Hepatitus delta virus (satellite virus)-> Hep B (host); much more dangerous w/ satellite cell
Term
Prions
Definition
Subviral Agents:
-scariest of all; proteinacious infectous particles, exist as normal proteins in animal tissue, can bcome abnormally folded (clumps up & block function of brain) -> infectious thru mouth
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