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-smallest living unit -most basic unit *many different shapes, sizes and functions |
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Ovum, can been seen with naked eye |
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how many cells does the body have? |
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study of cells, relatively new due to discovery of microscopes |
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of or for a bow (posion arrow) |
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-major ones in body (make up 96% of body weight) *oxygen *carbon *hydrogen *nitrogen |
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other major elements found in body |
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Potassium(K), Sodium (Na) Magnesium (Mg) and Calcium (Ca) |
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most abundant COMPOUND in a human boday is.... |
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WATER, H20 60% of body weight |
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classes of compounds -organic |
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contain carbon atoms, connected in chains to other carbon atoms or hydrogen and present in living organisms |
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classes of compounds -inorganic |
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have either no carbons or single carbons |
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examples of inorganic compounds |
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-water -atmospheric gases -electrolytes -acids -bases -salts |
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-carbs -lipids -proteins -nucleotides |
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- Obtains nutrients and other essential substances - Disposes of waste, maintains shape and integrity - Replicate - Organelles carry out the cell’s functions - Three main parts to cell: plasma membrane, cytoplasm, nucleus |
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plasma membrane -structure |
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-Phospholipid bilayer with proteins embedded (proteins can move around within bilayer) -Polar “head” is charged (and attracted to water – TERM?), nonpolar tail has fatty acid chains that avoid water (TERM?); tail-to-tail organization |
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plasma membrane -components |
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-Cholesterol (affects fluidity and stability, esp. in cold) -Glycolipids- small amount, function not known too well, believed to be cell recognition; ~10% of outer lipids -Proteins- control cell membrane function |
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plasma membrane -membrane protein functions~integral peripheral |
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-Transport - Communication (ion channels, hormone receptors) - Sugar chains attach to integral proteins and form external cell surface |
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plasma membrane -function |
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-Protective barrier -Receptors (proteins can allow some substances to bind) -Controls passage of molecules into and out of cell – divides intracellular and extracellular fluid -Largest molecules (macromolecules) travel via vesicular (bulk) transport |
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bulk transport -exocytosis |
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-exo=out of -Most secretion processes (e.g., mucus) -Substance is housed in vesicle (membrane sac) -Proteins vesicle membrane and plasma membrane to bind |
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bulk transport - endocytosis |
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-endo = into Substance is taken into folding part of plasma membrane, vesicle formed and pinched off -Phagocytosis (“celleating”) -Pseudopods engulf material, forming phagosome – often fuses with lysosomes (more on these later) -Pinocytosis (aka fluidphase endocytosis or “cell drinking”) -Receptor-mediated endocytosis |
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-Internal to plasma membrane, external to nucleus -Fluid, 80-90% water, rest is dissolved or suspended |
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-Small functional units within cell, most have their own membrane (similar to plasma membrane) -Location where metabolism takes place |
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-Temporary structures – may or may not be present in given cell type (e.g., pigments, food stores) |
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-Synthesizes CHO and is involved in secretions -Combines the CHO with proteins to form glycoproteins that accumulate in channels of Golgi -When channels get full, vesicles break off, are carried to cell membrane, and are released from cell (what is this process called?) OR go to lysosomes (or cell membrane) -Does sorting, processing, and packaging |
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-relatively large (about the size of mitochondrion |
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cells that secrete a lot, like pancreas, salivary glands |
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Lysosomes and Peroxisomes function |
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Lysosomes and Peroxisomes size |
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LOTS found in liver, kidneys |
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Network of rods in cytosol that supports structures and cell movements |
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Network of rods in cytosol that supports structures and cell movements |
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-microtubules -microfilaments -intermediate filaments |
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-Largest diameter, all come from centrosome, made of protein -Stiff but bendable – give cell shape and organize organelles |
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-Thinnest elements -Strands of actin (protein) – interact with myosin for cell contraction (more in muscle section) |
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tough, insoluble protein fibers- most stable |
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-Spherical structure in cytoplasm near nucleus -No membranes, contains matrix (helps with growth of microtubules) and centrioles |
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-Lie perpendicular to each other, barrel-shaped -Help form cilia, flagella, and mitotic spindle |
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Directs protein synthesis- hence,regulates cell activity(contains DNA) |
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Largest single organelle in cell (up to ½ celldiameter ~5 micrometers) |
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Not all nuclei are located in center of cell; Some cells, like muscle are multinucleated; One cell, the red blood cell (RBC) is anucleated |
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protein synthesis -transcription |
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DNA is a double-stranded helix that gets split and coded to mRNA |
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protein synthesis -translation |
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inside ribosome, RNA gets changed to proteins |
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orgenelles involved in protein synthesis |
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nucleus, ribosome, ER, Golgi |
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overview of protein synthesis |
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-transcription -mRNA goes into cytosol and over to a ribosome -translation -Proteins go out into ER and are stored, transported -If transported, proteins go to Golgi for modification, packaging |
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