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2.2 Biochemistry
Enzymes and Digestion
43
Biology
9th Grade
10/29/2011

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Term
     Chemical reaction
Definition
  • process that changes or transforms one set of chemicals into another
Term
          Reactants
Definition
  • the elements or compounds that enter into a chemical reaction
Term
        Products
Definition
  • Elements or compounds produced by a chemical reaction
Term
What happens to chemical bonds during chemical reactions?
Definition
  • chemical reactions always involve changes in chemical bonds that join atoms and compounds
Term
Energy in chemical reactions
Definition
  • reactions that release energy often occur spontaneously
  • reactions that absorb energy need a source
Term
Enzyme
Definition
  • proteins that act as biological catalysts
  • speed up the rate of chemical reactions in the cells
Term
How do enzymes speed up the rate of chemical reactions?
Definition
  • lower the activation energy, which has a dramatic effect on how quickly reaction is completed
Term
  Substrate
Definition
  • the reactants of enzyme catalyzed reactions
Term
 Active site
Definition
  • site on an enzyme where the enzyme and substrates bind together
Term
Coenzyme
Definition
  • small molecules needed in some enzyme reactions to help the reaction work properly
Term
        Inhibition
Definition
  • reduce or destroy the activity of an enzyme
  • two types: competitive and non-competitive 
Term
 Competitive Inhibitors
Definition
  • bind with the active site of an enzyme (compete with the  substrate for the site and block it
  • many are released from active site so enzyme can be regenerated; the higher the concentration of the substrate, the less effect inhibitor has
Term
Non-competitive Inhibitors
Definition
  • doesn't bond to active site, binds with a different part of the enzyme, which distorts the shape of enzyme so it can't function properly
  • not released from enzyme molecule so enzyme can't be regenerated
  • even a low concentration of a non-competitive inhibitor can be dangerous
Term
How do enzymes speed up the          rate of a chemical reaction?
Definition
  • they lower the activitation energy, which dramatically affects the rate of a chemical reaction
Term
Why are enzymes so important to the chemistry of living things?
Definition
Without enzymes, your body wouldn't be able to carry out the chemical reactions it needs to, and you would surely die.
Term
Digestion
Definition
  • the process of breaking down food into small molecules that can be passed to the cells that need them
  • Chemical: breaking down macromolecutles into subunits
  • Mechanical: physical breakdown of food into smaller  pieces
Term
Organs and tissues of digestive tract
Definition
  • Mouth
  • Salivary glands 
  • Pharnyx
  • Esophagus
  • Stomach
  • Small intestine
  • Large Intestine
  • Gallbladder
  • Pancreas
  • Rectum
  • Anus
Term
Mouth 
Definition
  • Beginning of digestive system
  • Mechanical -Tears and grinds food into pieces small enough to swallow
  • Chemical-saliva for moisture,cleaning tasting AND Starch Disgestion begins with salivary amylase
Term
Salivary Glands
Definition
  • release saliva, which moistens food an helps to swallow; contains amylase, which breaks down starches
Term
Pharynx
Definition
  • food and air passes through pharnyx
Term
Esophagus
Definition
  • tubular passageway to the stomach that food is pushed into when swallowed
  • Lined with mucus
  • contractions of muscle peristalsis push food toward stomach
Term
Functions of Digestive System
Definition
  • Digestion
  • Absorption-molecules absorbed into blood carried to cells in body
  • Elimination-wastes are are removed from body
Term
stomach
Definition
  • j shapedmuscular pouch (empty: 50ml, full: 4000ml)
  • mechanical digestion - churn and mix food via contractions until a mixture called chyme (kym) flows into ....
  • chemical digestion - hydrochloric acid makes the contentsof the stomach very acidic and Pepsin enzyme, whose precusor is the secretion pepsinogen, works to begin the digestion of protein, both secreted via glands in the stomach (NB amalyse is stopped and carbs are not digested again until the small intestine)
Term
Small Intestine
Definition
  • pushed through the pyloric valve to where almost all digestive enzymes enter this 20 ft. long tube-like structure
  • most of chemical digestion and absorption of nutrients occurs here
  • Chem. Digest.:
    • Carbs: maltase, sucrase, lactase enzymes break down remaining diaccharides into monsaccharides
    • Proteins: Proteinases or peptidase enzyme breaks down dipeptides into amino acids
Term

Helper Organs to Small Intestine: Liver, Gallbladder, Pancreas

NB: crucial function BUT food never enters them

Definition

Liver: produces bile which separates(emulsifies) fat molecules which makes it possible for enzymes to break down smaller fate molecutels. Bile stored in Gallbladder.

The Pancreas neutralizes stomach acids and secretes sodium bicarbonate and produces 3 enzymes:

 

  • amylase breaks down starch
  • trypsinogin in the gastric juice is actived by enzyme into trypsin that breaks down protein
  • Lipase breaks down of fat
Term
Villi
Definition
Small Intestine covered with finger-like projections wherein each one is a network of blood capillaries and lymph vessels that absorb and carry away nutrients 
Term
Large Intestine: Colon
Definition
  • 5ft long
  • food remains 12-24 hours
  • Job: Remove Water from undigested material that is left (big blow dryer)
  • Many bacteria live in colon, some secrete Vitamin K
  • absorb too little water: diarrhea, too much: constipation these are digestive system disorders along with ulcers
Term
Rectum
Definition

The undigested food would then be moved on to the last muscular part of the large intestine

 

The muscle process contracting and expanding called peristalsis moves undigested food to this last temorary holding place

Term
Anus
Definition
Undigested food is removed through this last valve
Term
Effect on Enzyme Concentration on rate of enzyme reaction
Definition
the rate will increase but only until the surface of the substrate is full then it will remain the same as there is no space for the enzyme to bond with the substate
Term
Effect of rate of enzyme reaction on sustrate concentration
Definition
it will increase in speed to a point and then max off as the enzyme-substrate complet is completed
Term
Effect of rate of enzyme reaction with Temperature
Definition
temperature affects many enzymes, those produced by human cells generally work best at temps close to37*C the normal temp of the human body
Term
Effect of pH on rate of an enzyme reaction
Definition
 there are pH for optimal enzyme stability and we have seen certain enzymes work well at different pH mouth and intestine low pH and Stomach high pH. certain extreme pH can stop enzyme reaction like Carb digestion in the stomach.
Term
salt concentrations affect on the rate of enzyme reaction
Definition
Term
Salivary amylase 
Definition
  • enzyme in saliva that breaks chemical bonds in starches and releases sugars
Term
Hydrochloric acid
Definition
  • produced by glands in stomach, makes stomach acidic
  • activates pepsin
Term
Bile
Definition
  • dissolves and disperses droplets of fat in fatty foods
  • makes it possible for enzymes to reach the smaller fat molecules and break them down
Term
Pepsin
Definition
  • enzyme that begins digestion of protein 
  • works best under acidic conditions in the stomach
Term
Trypsin
Definition
  • continues breakdown of protein
Term
Lipase
Definition
  • breaks down fat
Term
Amylase
Definition
  • continues the breakdown of starch
Term
Maltase, sucrase, and lactase
Definition
  • Break down remaining disaccharides into monosaccharides
Term
Peptidase 
Definition
  • Breaks down dipeptides into amino acids
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