Term
| What percentage of the population is affected by schizophrenia? |
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Definition
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Term
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Definition
-Disorganized, irrational thoughts
-Delusions
-Hallucinations |
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Term
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Definition
-Flat affect
-Alogia (no speech)
-Anhedonia (inability to feel pleasure) |
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Term
| What is the rule of thirds when it comes to treatment? |
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Definition
-1/3 have only one psychotic episode, then return to normal
-1/3 are treated with drugs and can function
-1/3 no effective treatment |
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Term
| What are some of the possible causes of schizophrenia? |
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Definition
-Genetics
-Environment
-season of birth
-prenatal virus
-prenatal malnutrition
-prenatal stress |
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Term
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Definition
| People born in late winter/early spring have increased risk |
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Term
| What two structural brain abnormalities are related to schizophrenia? |
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Definition
-Enlarged ventricles
-Reduction in cortex tissue (frontal/temporal lobes) |
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Term
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Definition
Low activity of neurons in the PFC
-responsible for negative symptoms |
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Term
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Definition
There is an overactive or hypersensitive DA system in many forms of schizophrenia
-drugs that decrease DA treat it
-drugs that increase DA increase positive symptoms |
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Term
| Which parts of the brain show altered numbers of DA receptors in schizophrenics? |
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Definition
| PFC and nucleus accumbens |
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Term
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Definition
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Term
| What effect do classical/typical antipsychotics have on schizophrenics? |
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Definition
| Large effect on positive symptoms |
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Term
| Extrapyramidal symptoms (EPS) |
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Definition
Motor/movement side effects of antipsychotic drugs
-rigidity, tremors, restlessness, immobility |
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Term
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Definition
Hormonal side effects of antipsychotics
-abnormal lactation/menstruation, impotence, weight gain |
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Term
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Definition
Head/digestive antipsychotic side effects
-blurred vision, congestion, dry mouth,constipation, trouble peeing |
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Term
| Atypical antipsychotic drugs (4) |
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Definition
More effective in treating negative symptoms
-reduce symptoms in 30% of those who did not respond previously
-minimal EPS effects
-can cause a decrease in white blood cells |
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