Term
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Definition
| Mutation that alters a single base |
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Term
| Base Substitution Mutation |
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Definition
| The substitution of one base pair for another |
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Term
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Definition
| If the new codon from the base substitution still encodes the same amino acid |
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Term
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Definition
| When the base substitution changes an amino acid in a protein, in turn changing the sense of the codon produced. |
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Term
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Definition
Transition changes pyrimidine base pairs to a different pyrimidine base pair or purine base pair to different purine
Transversion changes pyrimidine to purine or purine to pyrimidine |
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Term
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Definition
| When a base is changed that causes a transcribed codon to a stop codon which doesnt make sense to the translation apparatus |
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Term
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Definition
| The addition or deletion of a single base which causes an altered reading frame in the mRNA downstream of the mutation |
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Term
| Triple Repeat Expansion Mutations |
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Definition
| A triplet sequence of DNA that is repeated |
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Term
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Definition
| Any mutation that affects chromosomal structure |
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Term
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Definition
| Loss of a portion of a chromosome |
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Term
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Definition
| The duplication of a region of chromosomes which may lead to phenotypic consequences. |
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Term
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Definition
| Occurs next to the original region. |
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Term
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Definition
| Results when a segment of a chromosome is broken in two places, reversed, and put back together. |
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Term
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Definition
| Wen a piece of one chromosome is broken off an joined to another chromosome. |
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