Term
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Definition
-capsid w/ double stranded DNA -from the herpese viridae family Causes two distinct infections: Chicken pox and Herpes Zoster (shingles) |
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Term
| Spread of Varicella Zoster |
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Definition
-virus enters via nasopharynx Primary viremia - spreads to lymph nodes, liver and spleen Secondary viremia - from liver and spleen to skin and other regions (like nerves) |
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Term
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Definition
Caused by Varicella Zoster virus Hallmark are skin lesions starting on trunk and moving outwards -highly contagious -patients are infectious 48 hours before onset of rash |
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Term
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Definition
-found in 90% of the population -those over 60 are most susceptible to reactivation |
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Term
| Complications of Varicella Zoster |
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Definition
-secondary bacterial infections (stre. pyogenes of staph aureus) -meningeal irritation seen 21 days after onset of chickenpox in children |
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Term
| Herpes Zoster Reactivation |
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Definition
aka. Shingles -reactivation of latent VZV that usually occurs in 6th to 8th decades of life -unilateral eruption within a dermatome (often with severe pain) eg. only one side of face is affected -infection of trigeminal nerve often involves the face |
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Term
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Definition
| infection of ophthalmic branch of trigeminal nerve with Varicella Zoster |
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Term
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Definition
| when drugs are administered to prevent a disease (or in secondary prophylaxis, to prevent the worsening of the condition) |
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Term
| Administration of prophylaxis measures for Herpes Zoster |
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Definition
| administration of zoster immune globulin (ZIG) or VZIG should be given within 72 hours (and up to 96 hours) of infection |
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Term
| treatment of Herpes Zoster |
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Definition
Oral Acyclovir famciclovir Pain releivers Note: No asprin for those under 19 because it can cause Reys syndrom where fatty degeneration of the liver and encephalitis occurs. |
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Term
| Organisms that Cross the Placenta |
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Definition
ToRCHeS TOxoplasmosis Rubella Cytomegalovirus HErpes and HIV Syphillis |
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