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sympathetic nervous system (epinephrine) is fight or flight which is an antagonist to |
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the parasympathetic nervous system (acetylcholine). calms you down |
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– small, ovoid cells with spiny processes Phagocytes that monitor the health of neurons
phagocytes that live in brain and spinal cord. Job is to eat up bacteria that can cause damage |
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– range in shape from squamous to columnar They line the central cavities of the brain and spinal column
- line the cavities of your spinal cord and brain. Brain has 4 cavaties full of cerebral spinal fluid.
- have cilia and move the cerebral fluid around the brain and spinal cord.
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surround neuron cell bodies with ganglia
- hover around nerve cell bodies |
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Armlike extensions from the soma Called tracts in the CNS and nerves in the PNS There are two types: axons and dendrites
outgoing info goes down the axon and out through the boutons
incoming messages comes in through the dendrites
axons and dendrites. Dendrites are shorter, diffusely branched, receptive (take in information to send in the body (the soma)) . the electrical signals on a dendrite are not action potentials;They are called graded potentials.
On the axons the electrical signals are always action potentials. Movement can be in two directions. Anterograde (toward the axon terminal) or retrograde (away from the axon terminal)
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Slender processes of uniform diameter arising from the hillock long ones are called nerve fibers usually one unbranched per neuron |
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– branched terminus of an axon |
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Generate and transmit action potentials Secrete neurotransmitters from the axonal terminals |
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Movement along axons occurs in two ways |
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Anterograde — toward axonal terminal
Retrograde — away from axonal terminal |
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Envelopes an axon in a trough Encloses the axon with its plasma membrane Has concentric layers of membrane that make up the myelin sheath |
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– remaining nucleus and cytoplasm of a Schwann cell |
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Nodes of Ranvier (Neurofibral Nodes) |
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Gaps in the myelin sheath between adjacent Schwann cells They are the sites where axon collaterals can emerge |
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Action potentials, or nerve impulses, are: |
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Electrical impulses carried along the length of axons Always the same regardless of stimulus The underlying functional feature of the nervous system |
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– measure of potential energy generated by separated charge |
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voltage measured between two points
the bigger the difference the bigger the potential. |
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the flow of electrical charge between two points
how many electrons flowing along the axon |
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hindrance to charge flow
what keeps the electrons from flowing. |
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– substance with high electrical resistance |
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substance with low electrical resistance |
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Occurs when current passes through a myelinated axon only at the nodes of Ranvier. |
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Ions flow along their _______ when they move from an area of high concentration to an area of low concentration Ions flow along their _______ when they move toward an area of opposite charge |
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Voltage changes are decremental Current is quickly dissipated due to the leaky plasma membrane Only travel over short distances |
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Nerve fibers are classified according to: |
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Diameter, Degree of myelination. and the Speed of conduction |
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A junction that mediates information transfer from one neuron: To another neuron To an effector cell |
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Types of Synapses between the axon of one neuron and the dendrite of another |
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Types of Synapses between (axon to axon) |
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Types of Synapses between dendrite to dendrite) |
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Types of Synapses (dendrites to soma) |
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- Neurotransmitter receptors mediate changes in membrane potential according to the amount of neurotransmitter released and the amount of time the neurotransmitter is bound to receptors. |
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–
- dopamine, norepinephrine (NE), and epinephrine. Enzymes present in the cell determine length of biosynthetic pathway. Norepinephrine and dopamine are synthesized in axonal terminals. Epinephrine is released by the adrenal medulla.
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Neurotransmitters: Amino Acids |
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Include: GABA – Gamma ()-aminobutyric acid Glycine Aspartate Glutamate Found only in the CNS |
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Neurotransmitters: Novel Messengers |
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ATP Is found in both the CNS and PNS Produces excitatory or inhibitory responses depending on receptor type Induces Ca2+ wave propagation in astrocytes Provokes pain sensation |
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Neurotransmitters: Novel Messengers |
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Nitric oxide (NO) Activates the intracellular receptor guanylyl cyclase Is involved in learning and memory Carbon monoxide (CO) is a main regulator of cGMP in the brain |
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Inhibitory neurotransmitters |
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cause hyperpolarizations (e.g., GABA and glycine) |
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- : neurotransmitters that open ion channels
- Promote rapid responses
- Examples: ACh and amino acids
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- : neurotransmitters that act through second messengers
- Promote long-lasting effects
- Examples: biogenic amines, peptides, and dissolved gases
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Growth is guided by scaffold laid down by older neurons, orienting glial fibers, release of nerve growth factor by astrocytes, neurotropins released by other neurons, repulsion guiding molecules, and attractants released by target cells.
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Neuroglia (supporting cells)- |
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Provide a supportive scaffolding for neurons, Segregate and insulate neurons, Guide young neurons to the proper connections, Promote health and growth |
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are a brief reversal of membrane potential with total amplitude of 100 mV.
are only generated by muscle cells and neurons. They do not decrease in strength over distance. They are the principal means of neural communication.
in the axon of a neuron is a nerve impulse. |
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- - Substance P (mediator of pain signals), Beta endorphin, dynorphin, and enkephalins. Act as natural opiates; reduce pain perception. Bind to the same receptors as opiates and morphine. Gut-brain peptides – somatostatin, and cholecystokinin.
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neurotransmitters cause depolarizations (e.g., glutamate) |
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Functional groups of neurons that integrate incoming information and forward the processed information to its appropriate destination. |
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- – interpretation of sensory input. In the integration area the gray mater of the brain and spinal cord are where the cells are that make the decisions. And when they make a decision they send an input out to the muscles (the motor output)
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response to stimulistem. Send message to arm muscles get hand outta fire. |
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: a body, axon and dendrites. Born w/ all the nerves you will ever have. Have a high metabolic rate (always doing something) so they have a bunch of mitchondrria. Function is to send electrical signals, as well as signaling each other during development. |
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36 Interneuron(association neurons)- |
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has unmyelinated axons. makes the decision. In comes the sense (ow hand on fire) out goes motor (pull hand outta fire) 1:51 |
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theres bodies and unmyelinated axons. |
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Yes cause in white matter, white matter has myelin |
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do motor fibers have myelin on their axons?
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Yes cause in the white matter. White matter has myelin |
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Do sensory fibers have myelin around their axons? |
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? No because they are in the grey matter. Grey matter has no myelin |
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Do interneurons have myelin around their axons? |
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.(insulators and conductors) |
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Have 2 things in body
- ___________– keep electricity from flowing where you don’t want it. That’s why axons are covered with myelin.
__________ substance with low electrical resistance Ion channels |
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Electrical Current and the Body |
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- - Reflects the flow of ions rather than electrons. There is a potential on either side of membranes when:
- The number of ions is different across the membrane
- The membrane provides a resistance to ion flow
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