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10. Neurology
Rapid Review - First Aid
31
Medical
Professional
07/24/2015

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Term
Unilateral, severe periorbital headache with tearing and conjunctival symptoms
Definition
Cluster Headache

[Look for HA with eye problems]
Term
Prophylactic treatment for migraine
Definition
Antihypertensives (BBs or CCBs)
Antidepressants
Anticonvulsants
Dietary changes
Term
The MC pituitary tumor? Tx?
Definition
Prolactinoma
Tx: DA Agonists - Bromocriptine
Term
A 55yo patient presents with acute "broken speech." What type of aphasia? What lobe and vascular distribution?
Definition
-Broca's Aphasia (Expressive).
-Frontal Lobe lesion
-Left MCA distribution

[Broca = Can't speak from your Boca. Normal comprehension]
Term
The MCC of SAH
Definition
MC: Trauma
2nd MC: Berry Aneurysm
Term
A crescent-shaped hyperdensity on CT that does not cross the midline
Definition
Subdural Hematoma--Bridging veins torn
Term
A history significant for initial AMS with an intervening lucid interval.
-Dx?
-Most likely source?
-Tx?
Definition
Dx: Epidural Hematoma
Source: Middle meningeal artery rupture
Tx: Neurosurgical evacuation (burr hole)
Term
CSF findings with a SAH
Definition
-Elevated ICP
-RBCs
-Xanthrochromia (yellow CSF if RBCs lysed)
Term
Albuminocytologic dissociation
Definition
Guillain-Barre Syndrome
-Increased CSF Protein without significant increase in cell count
Term
Cold water is flushed into a patient's ear and the fast phase of the nystagmus is toward the opposite side.

Normal or pathologic?
Definition
Normal

[COWS--Cold Opposite, Warm Same]
Term
The MCC primary sources of mets to the brain
Definition
"Lots of Bad Stuff Kills Glia"

Lungs
Breast
Skin (Melanoma)
Kidneys (Renal Cell Carcinoma)
GI (Colorectal Cancer)
Term
May be seen in children who are accused of inattention in class and confused with ADHD.
Dx?
Tx?
Definition
Dx:Absence seizures
Tx: Ethosuximide (DOC). 2nd line: Valproic Acid
Term
The most frequent presentation of intracranial neoplasm
Definition
-Headache

Primary neoplasms are much less common than brain mets
Term
The MCC of seizures in:
-Children age 2-10?
-Young adults age 18-35?
Definition
2-10:
-Infection
-Febrile seizure
-Trauma
-Idiopathic

18-35
-Trauma
-Alcohol withdrawal
-Brain tumor
Term
Status Epilepticus Tx?
Definition
1- IV BZD (Lorazepam or Diazepam)
2- Phenytoin or Fosphenytoin

If still unresolved:
3- Sedate (Propofol) and intubate
4- Phenobarbitol or Pentobarbitol
Term
Confusion, confabulation, ophthalmoplegia, ataxia
Definition
Wernicke's encephalopathy
-Due to thiamine deficiency

[Always give glucose with thiamine to obtunded patients of unknown cause--glucose alone will use up thiamine worsening Wernicke's encephalopathy]
Term
What % lesion is an indication for carotid endarterectomy?
Definition
70% if stenosis is symptomatic
Term
MCC of dementia?
Definition
#1: Alzheimers
#2: Vascular / Multi-infarct
Term
A combined UMN and LMN disorder
Definition
ALS
Term
Rigidity and stiffness with unilateral resting tremor and masked facies
Definition
Parkinson's disease

[Bradykinesia, Pill rolling tremor, shuffling/festinating gait, masked facies]
Term
Parkinson's Disease Tx?
Definition
-Levodopa/Carbidopa
-DA Agonists (Ropinrole, Pramipexole, Bromocriptine)
-Apomorphine (DA agonist for rescue Sx)
-Selegiline (MAO-B Inhibitor)
-COMT Inhibitors: Entacapone or Tolcapone (not for monotherapy)
-Amantadine
-Surgical Pallidotomy or Deep Brain stimulators
Term
Treatment for Guillain-Barre Syndrome
Definition
IVIG or plasmaphoresis

Avoid Steroids
Term
Rigidity and stiffness that progress to choreiform movements accompanied by moodiness and altered behavior
Definition
Huntington's disease
Term
A 6yo girl presesnts witha port-wine stain in the V1 distribution as well as with mental retardation, seizures and ipsilateral leptomeningeal angioma.

Dx?
Tx?
Definition
Dx: Sturge-Weber Syndrome
Tx: Treat symptomatically. Possible focal cerebral resection of the affected lobe
Term
Multiple cafe-au-lait spots on the skin
Definition
Neurofibromatosis I
Term
Hyperphagia, Hypersexuality, hyperorality, and hyperdocility
Definition
Kluver-Bucy Syndrome (Amygdala)
Term
May be administered to a symptomatic patient to diagnose myasthenia gravis
Definition
Edrophonium
Term
Vwertigo, hearing loss, tinnitus or ear fullness. May have nausea or vomiting.
Dx?
Tx?
Definition
Dx: Meniere's Disaese
Tx:
-Low sodium diet
-Diuretics
-Anti-migraine meds
Term
Fluctuating fatigable ptosis or double vision.
Bulbar symptoms (dyarthria or dysphagia)
Proximal muscle weakness.

Symptoms worsen as day progresses. Can fluctuate dramatically.

-Dx?
-Tx?
Definition
Dx: Myasthenia Gravis
Tx: Pyridostigmine (Anti-AChE)

[Anti-ACh Receptor Antibody in NMJ. A/w Thymoma]
Term
Symptoms similar to Myasthenia Gravis, except weakness decreases with use. History of Small Cell Lung Cancer.
Definition
Lambert-Eaton Myasthenic Syndrome

[Anti-Presynaptic Ca2+ Channel Ab in NMJ. Paraneoplastic syndrome]
Term
EMG findings in MG vs LEMS?
Definition
MG: Decremental response
LEMS: Incremental response
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