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100814 - Intro Worms/Cestodes
N/A
40
Immunology
Graduate
10/12/2014

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Cards

Term
Two types of clinically relevant helminths
Definition
Platyhelminthes (flatworms), Nemathelminthes (roundworms)
Term
Subdivisions of platyhelminthes
Definition
Cestodes (tapeworms), trematodes (flukes)
Term
Subdivision(?) of nemathelminthes
Definition
Nematoes (roundworms)
Term
Cestode (tapeworm) general properties
Definition
Long body, scolex (=head) w/ suckers and/or hooks, proglottid (reproductive segments)
Term
Trematode (fluke) general properties
Definition
Leaf-shaped, ventral/oral suckers
Term
Cestodes - Tegument? Body cavity? Digestive tract?
Definition
Tegument in skin absorbs nutrients from host. NO body cavity OR digestive tract
Term
Cestodes - head/neck, proglottids
Definition
Scolex = head, containing hooks, rostellum, suckers. Neck region - site of proglottid formation
Term
Cestodes -proglottid distribution
Definition
Immature by neck, get more mature down the body towards the feces
Term
Cestodes - general cycle? Which form causes damage (eggs/larvae/adults)
Definition
Intermediate host ingests eggs, larvae hatch and penetrate intestinal wall, the LARVAE cause damage. Adults in intestine have virtually no effect. Eggs or proglottidis can be found in feces and are diagnostic
Term
Fish Tapeworm - parasite name, mode of transmission, classification
Definition
Diphyllobothrium latum - ingestion --> intestinal --> cestode
Term
D. latum - definitive hosts (hosts that harbor sexually mature forms)
Definition
Humans, bears, minks, other animals
Term
D. latum - intermediate hosts/life cycle
Definition
Eggs passed in feces, they embryonate, hatch, larval stages picked up by WATER FLEA (crustacean), then by bigger FISH, who are the source for human infection
Term
D. latum - Sx
Definition
Epigastric pain, nausea, vomiting, occasional intestinal obstruction, diarrhea. *Occasional megaloblastic anemia due to low B12 (worm takes it)
Term
D. latum - Dx
Definition
Eggs w/ knob on bottom of shell; proglottids in feces
Term
D. latum - Tx
Definition
Niclosamide, Prazyquantel
Term
Dipylidiasis - parasite, transmission, classification
Definition
Dipylidium caninum, Ingestion --> Intestinal --> Cestode
Term
D. caninum - definitive hosts
Definition
Pet owners, esp. children
Term
D. caninum - intermediate hosts/life cycle
Definition
Gravid proglottids passed in feces and release egg packets contaning embryonated eggs; ingested by larval FLEA, penetrate and form cystercoid. Fleas transmit infection to humans; animals can transmit fleas to humans
Term
D. caninum - Sx
Definition
Abdominal discomfort, anal pruritus, diarrhea
Term
D. caninum - Dx
Definition
Eggs ("packet" appearance) or proglottids in feces
Term
D. caninum - Tx
Definition
Prazyquantel
Term
Beef tapeworm - parasite, transmission, classification
Definition
Taenia saginata - ingestion --> intestinal --> Cestode
Term
T. saginata - definitive hosts
Definition
Human
Term
T. saginata - intermediate host/cycle
Definition
OX & CATTLE must ingest grass contaminated with human feces + eggs/gravid proglottidis. Cysticercus (larval form) develops in their muscle tissue and larval form (not eggs) must be ingested by humans
Term
T. saginata - Sx
Definition
Abdominal discomfort, appendicitis, cholangitis (common bile duct infection), intestinal form more severe than T. solium but does NOT develop into cystercosis
Term
Pork tapeworm - parasite, transmission, classification
Definition
Taenia solium - ingestion --> intestinal OR tissue --> Cestode
Term
T. solium - definitive host
Definition
Human
Term
T. solium - intermediate host/cycle
Definition
Similar to T. saginata but PIG harbor the cysticerci; HUMANS can also be int. host if ingesting contaminated water/feces, cysticercosis develops
Term
T. solium - Sx
Definition
Less frequently symptomatic than T. saginata, but can develop into cysticercosis (tissue form)
Term
Taeniasis - Dx (Intestinal)
Definition
Eggs or gravid proglottidis in feces with characteristic shell
Term
Taeniasis - Tx (Intestinal)
Definition
Prazyquantel
Term
Cysticercosis
Definition
Tissue form of T. solium, can be asymptomatic, extracerebral (ocular, cardiac, spinal lesions and associated Sx) or cerebral (=neurocysticercosis, seizures, focal neurologic deficits, intracerebral lesions)
Term
T. solium - Dx (Tissue)
Definition
Antibody detection, high IgE and eosinophils, biopsy, imaging
Term
T. solium - Tx (Tissue)
Definition
Surgical removal; for neurocysticercosis, treat Sx: *anti-inflammatory corticoids* antiseizure med + antiparasite drugs (Albendazole, Mebendazole)
Term
Hydatid worm - parasite, transmission, classification
Definition
Echinococcus granulosus - Ingestion --> Tissue --> Cestode
Term
E. granulosus - definitive host
Definition
Dogs
Term
E. granulosus - intermediate host/cycle
Definition
Eggs in dog feces consumed by LIVESTOCK (SHEEP), cysts form, dogs ingest cysts. HUMANS can also ingest dog feces to be intermediate host
Term
E. granulosus - Sx (echinococcosis disease)
Definition
May be silent for YEARS. Hepatic, pulmonary, brain, bone, and heart involvement. Rupture of cysts can cause eosinophilia, increased IgE, anaphylactic shock
Term
E. granulosus - Dx
Definition
Antibody detection, confirm hydatid cyst with ultrasound/imaging + serology, fine needle biopsy
Term
E. granulosus - Tx
Definition
Surgical removal of cysts, but since they contain larvae, risk of rupture. Albendazole, mebendazole after
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