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10/31 Unsafe Kinghorn
herbs suck
16
Pharmacology
Graduate
11/12/2016

Additional Pharmacology Flashcards

 


 

Cards

Term
Incidence of Herb Poisoning
Definition
Dietary Supplements accounted for 27,619 or 2.57% of 1.07 million pediatric exposures
Term
DILIN Drug Induced Liver Injury network
Definition
hepatology paper published indicating patients had significant injury from herbals, body buiding supps, and etc
Term
Aristolochia sp.
Definition

(+) weight reduction, Aristolochia fangchi used for Stephania tetranda in belgium study

(-)renal disease7 loss of tubules, tumors

 

Aristolocha Fang; Group 1; cancer in humans

Arist. acids: group 2: probably cancer in humans

Term

Roots of Noni

 

Morinda citrif.

Definition

juice: dietary supp.

roots: (+)boils, fever

anthraquinones

1-hydroquinones: cancer (roots only) Group 2B: possible cancer to humans

Term

Ginko seeds

Ginko bilboa

Definition

more toxic than leaves

seeds grilled in cuisine

ginko toxin 4: analag of vit B6

(-)neurotoxic bc antivit B activity

revered w 30mg B6

Term

Comfrey

Symphytum officinale

Definition

(+) GI problems, ulcers

(-)1,2-dehrydopyrrolizidine alkaloids (retronecin) converted to toxic  pyrrole in liver interact w proteins & nucleic acids

(-)liver diease, cirrhosis

 

Term

Ephedra sinensis

Ma Huang

Definition

(-)stroke, MI, death

lots of cases reported to fda:banned

Term
DMAA
Definition

OxyElite pro: weight loss

nasal decongestant used is sports supps

(-) non-viral hepatitis

fda banned

similar to ephedra

Term
DMBA
Definition
Term
[image]
Definition

Aristolochic acid I, Aristolochic acid II

From: Aristolochia fangchi

Toxicity: Class 2A

 

Term
[image]
Definition

1-Hydroxyanthraquinone

From: Roots of Noni

Toxicity: Class 2B

Term
[image]
Definition

Ginkgotoxin (4'-O-methylpyridoxine)

Analog of vitamin B6 (pyridoxine)

Term
[image]
Definition

[image]

From: COMFREY LEAVES AND ROOTS

Toxicity: Interacts with nucleophiles, such as proteins and nucleic acids, and thus cause harmful effects.

 

Term
[image]
Definition

1,3-Dimethylamylamine [DMAA] (Methylhexanamine)

From: OxyElite Pro [original formulation]

 

Term
[image]
Definition

1,3-Dimethybutylamine [DMBA] (aka “AMP citrate”)

From: Supplements for weight loss

 

Term
[image]
Definition

Aegeline (N-[2-hydroxy-2(4- methoxyphenyl)ethyl]-3-phenyl-2-propenamide)

From: OxyElite Pro (new formulation)

 

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