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006 Immunity and Abnormal Responses
Vocab 006 Immunity and Abnormal Responses
36
Nursing
Undergraduate 1
05/19/2013

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Term
Acute rejection
Definition
Tissue rejection that develops several weeks after transplantation
Term
Allografts
Definition
Transplants between genetically different individuals but from the same species
Term
Antibodies (immunoglobulins - Ig)
Definition
Produced by B lymphocytes in response to a specific antigen challenge
Term
Antibody titer
Definition
Quantity of serum antibody required to react with a specific antigen
Term
Antigen
Definition
Agents that cause activation of the immune system
Term
Autografts
Definition
Tissues transplanted from one site of an individual to another site in the same individual
Term
Autoimmune disorders
Definition
Disorder that occurs when the immune system does not distinguish between self-antigens and non-self-antigens
Term
B Lymphocytes
Definition
Cell type that produces specific antibodies, regulates the antibody-mediated immune response, and develops into plasma cells and/or memory cells
Term
Basophils
Definition
White blood cells involved in the inflammatory response, usually associated with an allergic reaction
Term
Chronic/late rejection
Definition
Tissue rejection that occurs after months or years, involving gradual degeneration of the blood vessels
Term
Complement system
Definition
Cascade of protein reactions activated by the immune response to destroy the antigen
Term
ELISA
Definition
Enzyme-linked immunosorbent assay; a diagnostic test
Term
Eosinophils
Definition
A white blood cell usually associated with an allergic reaction or parasitic infection
Term
Gamma globulins
Definition
Serum protein antibodies produced by B lymphocytes
Term
Hyperacute rejection
Definition
Tissue rejection that occurs immediately after transplantation
Term
Immunity
Definition
The body's ability to respond and defend against foreign substances
Term
Immunosuppression
Definition
Techniques applied to reduce the host's immune response and prevent rejection
Term
Isografts
Definition
Transplants between identical genetic entities such as identical twins
Term
Leukocytes
Definition
White blood cells
Term
Lymphocytes
Definition
Mononuclear, nonphagocytic leukocytes found in the blood, lymph, and lymphoid tissue. Lymphocytes are immunologically competent
Term
Macrophages
Definition
A differentiated phagocytic monocyte that has migrated into the tissue
Term
Major histocompatibility complex
Definition
Group of genes coded for production of self antigens
Term
Memory cells
Definition
Specialized lymphocytes that "remember" an antigen after first exposure
Term
Monocytes
Definition
Agranulocytes and large circulating phagocytotic cells that develop into macrophages when leaving the blood vessels
Term
Neutrophils
Definition
Leukocytes that are the most abundant actively motile phagocyte
Term
Opportunistic microorganisms
Definition
Normally harmless organisms that can become pathogenic under the right conditions, such as lack of microbial competition
Term
Primary deficiency
Definition
Type of immunodeficiency that occurs when there is an abnormality of the immune system caused by a genetic defect
Term
Prophylactic
Definition
Preventive; used as a protective measure
Term
Secondary deficiencies
Definition
Immunodeficiencies that arise when damage is caused by an environmental factor such as infection, radiation, chemotherapy, or burns
Term
Serum sickness
Definition
A systemic reaction that occurs when immune complexes are present in many tissues
Term
T lymphocytes
Definition
A specialized lymphocyte that is responsible for cellular immunity
Term
Type I allergic reactions
Definition
Reactions caused by an allergen that is an antigen that stimultes the production of IgE's
Term
Type II allergic reactions
Definition
Reactions in which the antigen (either a normal body antigen or a foreign antigen) is present on the cell membrane
Term
Type III allergic reactions
Definition
Reactions in which an antigen binds with an antibody and forms a complex, which results in the activation of a complement system
Term
Type IV allergic reactions
Definition
Delayed responses caused by sensitized T lymphocytes to a specific antigen
Term
Xenografts
Definition
Transplants between different species such as pigs and humans
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